Reproducibility or Producibility? Metrics and their masters

Reproducibility of indicators and metrics is an important topic as it underlies an increasing part of the approach taken to research evaluation. But reproducibility of metrics is not the critical question. The more important question is around access to the data to create metrics, and around who owns the metrics and the transparency of the algorithms and data elements. In short, is it not about producibility rather than reproducibility? With Dimensions, Digital Science has taken a first step in making publication and citation data more openly available. But, perhaps more importantly, Dimensions links other types of data to the familiar bibliometrics landscape to allow the community to go beyond citation-based indicators. The team at Digital Science believes in the “separation of powers” - data should be developed and hosted by providers and the community should own the metrics used to measure itself. Work has started to collaborate with the scientometric and research management community to support their development and implementation of metrics based on the Dimensions data and platform

The use of polymeric meshes for Pelvic Organ Prolapse: current concepts, challenges and future perspectives

Pelvic organ prolapse (POP) is one of the most common chronic disorders in women, impacting the quality of life of millions of them worldwide. More than 100 surgical procedures have been developed over the decades to treat POP. However, the failure of conservative strategies and the number of patients with recurrence risk have increased the need for further adjuvant treatments. Since their introduction, surgical synthetic meshes have dramatically transformed POP repair showing superior anatomic outcomes in comparison to traditional approaches. Although significant progress has been attained, among the meshes in clinical use, there is no single mesh appropriate for every surgery. Furthermore, due to the risk of complications including acute and chronic infection, mesh shrinkage, and erosion of the tissue, the benefits of the use of meshes have recently been questioned. The aim of this work is to review the evolution of POP surgery, analyzing the current challenges, and detailing the key factors pertinent to the design of new mesh systems. Starting with a description of the pelvic floor anatomy, the article then presents the traditional treatments used in pelvic organ disorders. Next, the development of synthetic meshes is described with an insight into how their function is dependent on both mesh design variables (i.e., material, structure, and functional treatment) and surgical applications. These are then linked to common mesh‐related complications, and an indication of current research aiming to address these issues

The Nature of Optical Features in the Inner Region of the 3C48 Host Galaxy

The well-known quasar 3C48 is the most powerful compact steep-spectrum radio-loud QSO at low redshifts. It also has two unusual optical features within the radius of the radio jet (~1"): (1) an anomalous, high-velocity narrow-line component, having several times as much flux as does the narrow-line component coinciding with the broad-line redshift; and (2) a bright continuum peak (3C48A) ~1" northeast of the quasar. Both of these optical features have been conjectured to be related to the radio jet. Here we explore these suggestions. We have obtained Gemini North GMOS integral-field-unit (IFU) spectroscopy of the central region around 3C48. We use the unique features of the IFU data to remove unresolved emission at the position of the quasar. The resolved emission at the wavelength of the high-velocity component is peaked <~0.25" north of the quasar, at virtually the same position angle as the base of the radio jet. These observations appear to confirm that this high-velocity gas is connected with the radio jet. However, most of the emission comes from a region where the jet is still well collimated, rather than from the regions where the radio maps indicate strong interaction with an external medium. We also present the results of HST STIS spectroscopy of 3C48A. We show that 3C48A is dominated by stars with a luminosity-weighted age of ~1.4 X 10^8 years, substantially older than any reasonable estimate for the age of the radio source. Our IFU data indicate a similar age. Thus, 3C48A almost certainly cannot be attributed to jet-induced star formation. The host galaxy of 3C48 is clearly the result of a merger, and 3C48A seems much more likely to be the distorted nucleus of the merging partner, in which star formation was induced during the previous close passage.Comment: 10 pages, accepted by The Astrophysical Journa

The Effect of Variability on the Estimation of Quasar Black Hole Masses

We investigate the time-dependent variations of ultraviolet (UV) black hole mass estimates of quasars in the Sloan Digital Sky Survey (SDSS). From SDSS spectra of 615 high-redshift (1.69 < z < 4.75) quasars with spectra from two epochs, we estimate black hole masses, using a single-epoch technique which employs an additional, automated night-sky-line removal, and relies on UV continuum luminosity and CIV (1549A) emission line dispersion. Mass estimates show variations between epochs at about the 30% level for the sample as a whole. We determine that, for our full sample, measurement error in the line dispersion likely plays a larger role than the inherent variability, in terms of contributing to variations in mass estimates between epochs. However, we use the variations in quasars with r-band spectral signal-to-noise ratio greater than 15 to estimate that the contribution to these variations from inherent variability is roughly 20%. We conclude that these differences in black hole mass estimates between epochs indicate variability is not a large contributer to the current factor of two scatter between mass estimates derived from low- and high-ionization emission lines.Comment: 76 pages, 15 figures, 2 (long) tables; Accepted for publication in ApJ (November 10, 2007

ESO Imaging Survey VII. Distant Cluster Candidates over 12 square degrees

In this paper the list of candidate clusters identified from the I-band data of the ESO Imaging Survey (EIS) is completed using the images obtained over a total area of about 12 square degrees. Together with the data reported earlier the total I-band coverage of EIS is 17 square degrees, which has yielded a sample of 252 cluster candidates in the redshift range 0.2 \lsim z \lsim 1.3. This is the largest optically-selected sample currently available in the Southern Hemisphere. It is also well distributed in the sky thus providing targets for a variety of VLT programs nearly year round.Comment: 5 pages, 3 figures, submitted to Astronomy & Astrophysic

Associations between inattention and impulsivity ADHD symptoms and disordered eating risk in a community sample of young adults

BACKGROUND: Symptoms of attention deficit hyperactivity disorder (ADHD) and trait impulsivity have been associated with disordered eating but are seldom assessed in community studies, or longitudinally and little is known about the mediating mechanisms. METHODS: We tested associations between ADHD symptoms and disordered eating cross-sectionally and between trait impulsivity and disordered eating longitudinally. We utilised data from a normative cohort of young adults (642 participants: 65% female, M(age) = 23 years). Participants were classified as high risk or low risk for disordered eating using the SCOFF instrument. In the first two steps of both cross-sectional and longitudinal hierarchical logistic regression models, demographics and covariates were entered. For the cross-sectional regression, Adult ADHD self-report scale (ASRS) scores, separated into inattentive and hyperactive/impulsive symptoms, were entered in the third step. In a separate longitudinal model, Barratt impulsivity scale subscales (attentional, motor and non-planning impulsivity) were entered in the third step. Depression, as assessed by the moods and feelings questionnaire (MFQ), was examined as a mediator. RESULTS: Cross-sectionally, sex, MFQ score and inattentive symptoms predicted disordered eating risk (model R(2) = 20%). Longitudinally, sex, MFQ score and attentional impulsivity predicted disordered eating risk (model R(2) = 16%). The relationship between inattentive symptoms and the disordered eating risk was partially mediated by MFQ score, whereas the relationship between attentional impulsivity and the disordered eating risk was fully mediated by MFQ scores. CONCLUSIONS: These data highlight (1) a specific role for inattentive symptoms of ADHD and (2) the importance of both depression and impulsivity in predicting eating disorder risk

Spectral Variability of Quasars in the Sloan Digital Sky Survey. II: The C IV Line

We examine the variability of the high-ionizaton C IV line in a sample of 105 quasars observed at multiple epochs by the Sloan Digital Sky Survey. We find a strong correlation between the change in the C IV line flux and the change in the line width, but no correlations between the change in flux and changes in line center and skewness. The relation between line flux change and line width change is consistent with a model in which a broad line base varies with greater amplitude than the line core. The objects studied here are more luminous and at higher redshift than those normally studied for variability, ranging in redshift from 1.65 to 4.00 and in absolute r-band magnitude from roughly -24 to -28. Using moment analysis line-fitting techniques, we measure line fluxes, centers, widths and skewnesses for the C IV line at two epochs for each object. The well-known Baldwin Effect is seen for these objects, with a slope beta = -0.22. The sample has a median intrinsic Baldwin Effect slope of beta = -0.85; the C IV lines in these high-luminosity quasars appear to be less responsive to continuum variations than those in lower luminosity AGN. Additionally, we find no evidence for variability of the well known blueshift of the C IV line with respect to the low-ionization Mg II line in the highest flux objects, indicating that this blueshift might be useful as a measure of orientation.Comment: 52 pages, 14 figures, accepted for publication in Ap