Collapse of quasi-two-dimensional wet granular columns

This paper deals with the experimental characterization of the collapse of wet granular columns in the pendular state, with the purpose of collecting data on triggering and jamming phenomena in wet granular media. The final deposit shape and the runout dynamics were studied for samples of glass beads, varying particle diameter, liquid surface tension, and liquid amount. We show how the runout distance decreases with increasing water amount (reaching a plateau for $w>1 \%$) and increases with increasing Bond number, while the top and toe angles and the final deposit height increase with increasing water amount and decrease with decreasing Bond number. Dimensional analysis allowed to discuss possible scalings for the runout length and the top and toe angles: a satisfying scaling was found, based on the combination of Bond number and liquid amount.Comment: 8 pages, 14 figure

Superradiant light scattering from a moving Bose-Einstein condensate

We investigate the interaction of a moving BEC with a far detuned laser beam. Superradiant Rayleigh scattering arises from the spontaneous formation of a matter-wave grating due to the interference of two wavepackets with different momenta. The system is described by the CARL-BEC model which is a generalization of the Gross-Pitaevskii model to include the self-consistent evolution of the scattered field. The experiment gives evidence of a damping of the matter-wave grating which depends on the initial velocity of the condensate. We describe this damping in terms of a phase-diffusion decoherence process, in good agreement with the experimental results

STUDY REGARDING THE SANITARY-VETERINARY CONTROL OF THE CATTLE CARCASES WITHIN S.C. SIMONA S.R.L. SLAUGHTERHOUSE OF BALȘ

After the results obtained from the five samples collected from 6 carcases, we mayconclude that, out of the total 30 samples examined according to the values obtained in a logarithm with base 10, there were 5 satisfactory samples, 21 acceptable samples and 4 positive-valued unsatisfactory samples. The carcases samples were examined by means of the horizontal method of enumerating the total number of germs (NTG) according to SR EN ISO 4833/2003 by means of the technique of counting the colonies at 300C, obtaining values in ufc/cm2, that by changing into log10/cm2, we could spotlight the contamination degree of the cattle carcases within the microbiological norm (satisfactory, acceptable and unsatisfactory) according to the microbiological criteria stipulated in the (EC) Regulations no. 1441/2007, to the amendment of the (EC) Regulations no. 2073/2005 regarding the microbiological criteria for food products

Multicolor Licklider Transmission Protocol: An LTP Version for Future Interplanetary Links

The Licklider Transport Protocol (LTP) is the "convergence layer" of choice in Interplanetary networks based on Delay-/Disruption-Tolerant architecture. It was designed for long-delay scheduled-intermittent links, offering either a reliable or an unreliable service, with "red" and "green" parts, respectively. The aim of this article is to present multicolor LTP, an LTP version consisting in a series of enhancements of which the most significant are the use of monochrome sessions, the introduction of an additional orange color offering a "notified" service, and the definition of default link colors. After a thorough examination of basic LTP mechanisms for all color variants, this article discusses two scenarios where orange seems particularly appealing: video streaming and optical interplanetary links. Numerical results offer further insight into the complex LTP mechanisms and also highlight the difference between LTP retransmissions and bundle protocol retransmissions, the latter benefitting from routing reprocessing. Multicolor LTP has already been implemented as an interplanetary overlay network (ION) plug-in and its enhancements have been proposed to Consultative Committee for Space Data Systems Space Internetworking Services Delay-/Disruption-Tolerant Networking working group for a possible inclusion in the next version of LTP specifications (LTPv2)

MiR-205-5p inhibition by locked nucleic acids impairs metastatic potential of breast cancer cells

Mir-205 plays an important role in epithelial biogenesis and in mammary gland development but its role in cancer still remains controversial depending on the specific cellular context and target genes. We have previously reported that miR-205-5p is upregulated in breast cancer stem cells targeting ERBB pathway and leading to targeted therapy resistance. Here we show that miR-205-5p regulates tumorigenic properties of breast cancer cells, as well as epithelial to mesenchymal transition. Silencing this miRNA in breast cancer results in reduced tumor growth and metastatic spreading in mouse models. Moreover, we show that miR-205-5p knock-down can be obtained with the use of specific locked nucleic acids oligonucleotides in vivo suggesting a future potential use of this approach in therapy

Physiological effectors modify voltage sensing by the cyclosporin A-sensitive permeability transition pore of mitochondria.

This paper reports an investigation on the modulation of the mitochondrial permeability transition pore (MTP) by the membrane potential. Energized rat liver mitochondria loaded with a small Ca2+ pulse in sucrose medium supplemented with phosphate favor a high MTP "closed" probability because of the high membrane potential and therefore maintain a low permeability to sucrose. Upon depolarization by the addition of fully uncoupling concentrations of carbonyl cyanide p-trifluoromethoxyphenylhydrazone (FCCP) mitochondria favor a high MTP "open" probability and rapidly undergo a process of osmotic swelling following sucrose diffusion toward the matrix. A titration with FCCP reveals that discrete subpopulations of mitochondria with different gating potentials for MTP opening may exist, since increasing concentrations of FCCP increase the fraction of mitochondria undergoing osmotic swelling. We show that physiological effectors (Ca2+, Mg2+, ADP, palmitate) modify pore opening in a mitochondrial population by shifting the fraction of mitochondria with a functionally open pore at any given membrane potential. Many inducers and inhibitors may therefore affect the pore directly through an effect on the MTP voltage sensing rather than indirectly through an effect on the membrane potential. Thus, many effectors may induce pore opening by shifting the MTP gating potential to higher levels, whereas many inhibitors may induce pore closure by shifting the MTP gating potential to lower levels