43 research outputs found
Vanishing theorems for Shimura varieties at unipotent level
We show that the compactly supported cohomology of Shimura varieties of Hodge type of infinite -level (defined with respect to a Borel subgroup) vanishes above the middle degree, under the assumption that the group of the Shimura datum splits at . This generalizes and strengthens the vanishing result proved in "Shimura varieties at level and Galois representations". As an application of this vanishing theorem, we prove a result on the codimensions of ordinary completed homology for the same groups, analogous to conjectures of Calegari--Emerton for completed (Borel--Moore) homology
A quotient of the Lubin-Tate tower II
In this article we construct the quotient M_1/P(K) of the infinite-level
Lubin-Tate space M_1 by the parabolic subgroup P(K) of GL(n,K) of block form
(n-1,1) as a perfectoid space, generalizing results of one of the authors (JL)
to arbitrary n and K/Q_p finite. For this we prove some perfectoidness results
for certain Harris-Taylor Shimura varieties at infinite level. As an
application of the quotient construction we show a vanishing theorem for
Scholze's candidate for the mod p Jacquet-Langlands and the mod p local
Langlands correspondence. An appendix by David Hansen gives a local proof of
perfectoidness of M_1/P(K) when n = 2, and shows that M_1/Q(K) is not
perfectoid for maximal parabolics Q not conjugate to P.Comment: with an appendix by David Hanse
Monetary policy and bubbles in US REITs
In this article, we analyze the effects of monetary policy on the bubbles in the Real Estate Investment Trusts (REITs) sector of the United States. We use a time‐varying vector autoregressive model over the quarterly period of 1972:1 to 2018:1. We find protracted periods, starting from the onset of the recent financial crisis to the end of the sample period, where contractionary monetary policy is associated with increases in the bubble component in the REITs of the US economy. This result, which is robust to alternative REITs indexes, is contrary to the “conventional” view, as well as to the predictions of standard models of bubbles.http://wileyonlinelibrary.com/journal/irfihj2020Economic
The efficacy of angiotensin–I receptor blocker Valsartan in patients with cronic obstructive lung disease
Department of Chronic Obstructive Pulmonary Disease, Chiril Draganiuc Institute of Phthysiopulmonology, Department of Functional Diagnostic, Republican Diagnostic Medical Center, Chisinau, the Republic of MoldovaBackground: The purpose of this study was the clinical, functional and instrumental evaluation of efficacy and safety of angiotensin-I receptor
blocker Valsartan in patients with chronic obstructive pulmonary disease.
Material and methods: There were investigated 25 patients (mean age 50.5 ± 4.34 years) with moderate to severe forms of obstructive lung disease
– initial and after 5 weeks of treatment with angiotensin – I receptor blocker Valsartan (Nortivan, ,,Gedeon Richter’’, Hungary), mean dose 54.5 ± 15.4
mg once-daily, using standard ECG, EchoCG with Doppler, bodyplethysmography, ultrasound Doppler (for endothelial function estimation), pulmonary
diffusion capacity for CO, cycloergometry - initial and after short – term treatment with Nortivan.
Results: There were not detected any negative changes on bronchial permeability after the treatment. Significant improvement of endothelial function,
pulmonary diffusion capacity, parallel with considerable decreasing of pulmonary artery systolic and mean pressure and total bronchial resistance – were
observed after 5 weeks of treatment.
Conclusions: Nortivan is well-tolerated and highly effective in patients with moderate to severe forms of obstructive lung disease
Ultrasonografia cu substanţă de contrast în examinarea tumorilor renale. Comparaţie între un caz de oncocitom şi un caz de cancer cu celule renale şi studiu aprofundat al literaturii
Universitatea de Medicină şi Farmacie Iuliu Haţieganu, Cluj-NapocaIntroducere. Oncocitomul renal (OCR) reprezintă o tumoră benignă, a cărui diagnostic este în mod
frecvent incidental. Cancerul cu celule renale (CCR)
este cea mai frecventă patologie malignă renală.
Ultrasonografia este în mod frecvent prima linie
de evaluare a acestor formaţiuni, studiul fiind completat cu examinarea prin tomografie computerizată
cu substanţă de contrast (CECT).
Studiul prezintă două cazuri – OCR și, respectiv,
CCR. Printr-o amplă consultare a literaturii de specialitate, corelată cu experienţa de până în prezent,
se dorește identificarea aportului ultrasonografiei
cu substanţă de contrast (CEUS) în diagnosticul
tumorilor renale.
Materiale și metodă. Ambii pacienţi au fost de
sex feminin, vârsta fiind de 35 și, respectiv, 53 de ani.
Evaluarea imagistică a inclus, în ambele cazuri,
ecografia în mod B, Doppler color, pulsat, precum și
cu substanţă de contrast (SC) (Sonovue-Bracco, Italia,
1,6 ml intravenos în bolus). Caracteristicile captării și
spălării agentului de contrast au fost evaluate folosind un program dedicat (Sonoliver, Tomtec Imaging
Systems). S-au calculat pentru fiecare formaţiune și
pentru parenchimul martor următorii indici: Time to
peak (TTp), intensitatea maximă (IMAX), timpul de
spălare (RT), timpul mediu de tranzit (mTT). Investigaţiile au fost completate prin CECT.
Rezultate. Examinarea ultrasonografică a primei paciente a identificat o masă localizată la nivelul
corticalei rinichiului drept, hiperecogenă comparativ
cu aceasta, omogenă, bine delimitată. Formaţiunea
măsura 30/31/31 mm. Examinările Doppler color și
pulsat au relevat vascularizaţie periferică și centrală,
ce îmbrăca aspectul de ,,spiţe de roată”.
La introducerea substanţei de contrast, periferia
tumorii a prezentat captare intensă. IMAX atribuită
formaţiunii a fost inferioară parenchimului normal
(92,2% vs 100%). Valorile RT, TTp și mTT au fost superioare corticalei de referinţă (8,44s vs 6,01s; 17,59s vs
15,7s; 20,19s vs 16,97s). Centrul formaţiunii a captat
mai lent SC, rămânând hipocaptant.
Formaţiunea corticală stângă, identificată la cea
de-a doua pacientă, a fost inomogenă și relativ hipercogenă, comparativ cu parenchimul normal. Delimitarea tumorii, raportată la cazul precedent, nu a
fost la fel de netă. Dimensiunile au fost de 32/28,7/27
mm. Examinările Doppler color și pulsat au identificat
vascularizaţie bogată peritumorală. Post-CEUS, la
nivelul tumorii și a corticalei de referinţă s-au calculat
IMAX (84,95% vs 100%; ), RT (14,87s vs 16,6s), TTp
(16,96s vs 18,25s), mTT (49,41s vs 69,85s).
Examinarea CECT a primului caz consolidează
diagnosticul de oncocitom, iar la cel de-al doilea –
diagnosticul de CCR. Rezultatul anatomopatologic
al pieselor de rezecţie identifică leziunile ca OCR
și CCR.
Discuţii. Procesele de neovascularizaţie imprimă tumorilor renale o comportare aparte faţă
de corticala indemnă. În cazurile prezentate, indicii
CEUS măsuraţi pentru OCR și CCR sunt sensibil diferiţi atât între ei, cât și faţă de cei ai parenchimului
normal. Literatura de specialitate subliniază nevoia
unor studii ample, concentrate asupra diagnosticului
tumorilor renale prin intermediul CEUS.
Concluzii. Abilitatea CEUS de a detecta fluxuri
lente, capacitatea de cuantificare în timp real și posibilităţile de postprocesare pot fi considerate argumente
ce susţin validitatea metodei în cuantificarea tumorilor
renale. Constrângeri în cazul pacienţilor cu insuficienţă renală practic nu există. Cuantificarea curbelor de
spălare în cadrul unui lot semnificativ de pacienţi ar
putea identifica parametrii specifici OCR și CCR
Identifying networks in social media: The case of #Grexit
We examine the intensity of ‘#Grexit’ usage in Twitter during a period of economic and financial turbulence. Using a frequency-analysis technique, we illustrate that we can extract detailed information from social media data. This allows us to map the networks of interest as it is reflected in Twitter. Our findings identify high-interest in Grexit from Twitter users in key peripheral countries, core Eurozone members as well as core EU member states outside the Eurozone. Overall, our study presents a useful tool for identifying clusters. This is part of a new research agenda utilising the information extracted from big data available via social media channels
Monetary policy and bubbles in US REITs
In this article, we analyze the effects of monetary policy on the bubbles in the Real Estate Investment Trusts (REITs) sector of the United States. We use a time‐varying vector autoregressive model over the quarterly period of 1972:1 to 2018:1. We find protracted periods, starting from the onset of the recent financial crisis to the end of the sample period, where contractionary monetary policy is associated with increases in the bubble component in the REITs of the US economy. This result, which is robust to alternative REITs indexes, is contrary to the “conventional” view, as well as to the predictions of standard models of bubbles.http://wileyonlinelibrary.com/journal/irfihj2020Economic
Shimura varieties at level and Galois representations
We show that the compactly supported cohomology of certain or -Shimura varieties with -level vanishes above the middle degree. The only assumption is that we work over a CM field in which the prime splits completely. We also give an application to Galois representations for torsion in the cohomology of the locally symmetric spaces for . More precisely, we use the vanishing result for Shimura varieties to eliminate the nilpotent ideal in the construction of these Galois representations. This strengthens recent results of Scholze and Newton-Thorne
Shimura varieties at level and Galois representations
We show that the compactly supported cohomology of certain
U(n, n) or Sp(2n)-Shimura varieties with Γ1(p∞)-level vanishes above the middle degree. The only assumption is that we work over a CM field F in which
the prime p splits completely. We also give an application to Galois representations for torsion in the cohomology of the locally symmetric spaces for GLn/F.
More precisely, we use the vanishing result for Shimura varieties to eliminate
the nilpotent ideal in the construction of these Galois representations. This
strengthens recent results of Scholze [Sch15] and Newton-Thorne [NT16]