Amy's story: a research agenda for smoking cessation in pregnancy

The purpose of this paper is to report on a case from Nottinghamshire County Primary Care Trust (PCT) as an exploratory study examining the role of social marketing’s contribution to smoking cessation during pregnancy. Insights from the case will be used to inform and stimulate debate around future inquiry regarding the effectiveness of such campaigns, specifically with respect to smoking cessation in pregnancy, the role of low-budget highly-localised programmes and, in response to a recent Chartered Institute of Marketing (CIM) paper (Thorp, 2009), the extent to which social marketers lead the way in producing behavioural change in populations. Whilst well discussed in the health literature, smoking cessation during pregnancy remains under-researched in the marketing literature offering opportunities for research and practice. Also, this study is of contemporary interest in light of the proposed public sector cuts which will restrict social marketing budgets, the move of Public Health to local authority control placing it as central to the Government’s public health plans, and the Government’s reported interest in behavioural change techniques such as nudge theory (Stamp, 2010). The paper is structured by presenting the case using The National Social Marketing Centre’s (NSMC, 2010) benchmark criteria for effective social marketing, whilst identifying findings and themes from the literature

Allison Singley, Director of Parent Relations

In our new Next Page column, Allison Singley, Director of Parent Relations, shares with us the three books she is currently reading and why it might take her a while to finish them, her two desert island books (one of which inspired her doctoral dissertation), how she maintains a habit of reading poetry daily, and why she doesn’t write in books anymore — or feel the need to finish one

What do stroke survivors think about evidence based care they receive? Learning from insights at the periphery

Permission to archive the publisher pdf of this article was granted by the publisher in February 2012Rationale and aim of study: While exploring the experience of stroke survivors of secondary stroke prevention as part of a wider patient and public involvement service initiative, study participants willingly shared insights on other aspects of care that mattered to them. This is important as little is known about patients’ preferences for care. Methods: Data was generated from focus groups and semi-structured interviews that were held with 38 stroke survivors or their proxy respondents as part of an action research study. A framework analysis was used to examine data. Results: Our findings largely support current knowledge about the benefits of receiving evidence based stroke care. Although patients broadly appreciated being on a specialist unit, unexpectedly and contrary to best practice some expressed the wish to be treated elsewhere as they found the experience of being on a stroke unit difficult. Other findings included the need for more local peer support and difficulties surrounding transfer from hospital to home. Resultant actions included awareness training for staff about sensitively managing people’s perceptions about being on the stroke unit; development of shared computer based (IT) resources, and the establishment of a volunteer peer support system. Conclusion: The evidence base for the benefits of stroke unit care is unequivocal; however this model of care presents challenges for some. Involving patients in service development can inform small but key changes in practice that can help address inherent tensions in delivering evidence based services that are sensitive to patient preference.This project was funded by a grant from the Peninsula Primary Care Research Networ

Spatial curvature endgame: Reaching the limit of curvature determination

Current constraints on spatial curvature show that it is dynamically negligible: $|\Omega_{\rm K}| \lesssim 5 \times 10^{-3}$ (95% CL). Neglecting it as a cosmological parameter would be premature however, as more stringent constraints on $\Omega_{\rm K}$ at around the $10^{-4}$ level would offer valuable tests of eternal inflation models and probe novel large-scale structure phenomena. This precision also represents the "curvature floor", beyond which constraints cannot be meaningfully improved due to the cosmic variance of horizon-scale perturbations. In this paper, we discuss what future experiments will need to do in order to measure spatial curvature to this maximum accuracy. Our conservative forecasts show that the curvature floor is unreachable - by an order of magnitude - even with Stage IV experiments, unless strong assumptions are made about dark energy evolution and the $\Lambda$CDM parameter values. We also discuss some of the novel problems that arise when attempting to constrain a global cosmological parameter like $\Omega_{\rm K}$ with such high precision. Measuring curvature down to this level would be an important validation of systematics characterisation in high-precision cosmological analyses.Comment: 9 pages, 1 figure. Updated to match version published in Phys. Rev.

Implication of Sialidases in Salmonella Infection: Genome Release of Sialidase Knockout Strains from Salmonella enterica Serovar Typhimurium LT2.

Sialidases, which are widely distributed in nature, cleave the α-ketosidic bond of terminal sialic acid residue. These emerging virulence factors degrade the host glycan. We report here the release of seven sialidase and one sialic acid transporter deletion in Salmonella enterica serovar Typhimurium strain LT2, which are important in cellular invasion during infection

High-Speed Rail Projects in the United States: Identifying the Elements of Success-Part 2, MTI 06-03

In August 2005, the Mineta Transportation Institute issued the report, High-Speed Rail Projects in the United States: Identifying the Elements for Success. The report noted that since the 1960s, highspeed ground transportation (HSGT) has “held the promise of fast, convenient, and environmentally sound travel for distances between 40 and 600 miles.” After briefly discussing the different experiences with HSGT between the United States and its Asian and European counterparts, the report proceeded to review three U.S. cases—Florida, California, and the Pacific Northwest—as a means for identifying lessons learned for successfully implementing high-speed rail (HSR) in the United States. This report is, in essence, volume 2 of the previous study. Also using a comparative case study approach, this effort adds to the earlier work with three additional cases—the Chicago Hub, the Keystone Corridor, and the Northeast Corridor (NEC). As with the earlier report, the goal of this study is to identify lessons learned for successfully implementing HSR in the United States. Given the early stages of most of these projects, “success” is defined by whether a given HSR project is still actively pursuing development or funding. However, in the case of the Northeast Corridor, a fuller discussion of success is provided since HSR has been implemented on that corridor for some time now