6,890 research outputs found
Getter pumping
A surface may provide a useful pumping action when able to retain adsorbed gas molecules for the duration of a given experiment. To fulfil this condition at room temperature, strong binding forces, as those resulting from chemical reactions, are required. Materials able to react with gases to form stable chemical compounds are called getters. The two main families of getters (evaporable and non-evaporable, or NEG) are presented and discussed. Special emphasis is placed on the NEG strips currently used for the vacuum systems of particle accelerators, and on the newly developed NEG thin-film coatings, in view of their possible future applications
Pennatulacea described by Sebastiano Richiardi present in the Cnidaria collection of the Zoological Museum “La Specola” in Florence (Italy).
Non-singlet QCD analysis of F_2(x,Q^2) up to NNLO
The significance of NNLO (3-loop) QCD contributions to the flavor non-singlet
sector of F_2^ep and F_2^ed has been studied as compared to uncertainties
(different factorization schemes, higher twist and QED contributions) of
standard NLO (and LO) QCD analyses. The latter effects turn out to be
comparable in size to the NNLO contributions. Therefore the minute NNLO effects
are not observable with presently available data on non-singlet structure
functions.Comment: 14 pages, 2 figure
Implications of Hadron Collider Observables on Parton Distribution Function Uncertainties
Standard parton distribution function sets do not have rigorously quantified
uncertainties. In recent years it has become apparent that these uncertainties
play an important role in the interpretation of hadron collider data. In this
paper, using the framework of statistical inference, we illustrate a technique
that can be used to efficiently propagate the uncertainties to new observables,
assess the compatibility of new data with an initial fit, and, in case the
compatibility is good, include the new data in the fit.Comment: 22 pages, 5 figure
Structure Functions in Deep Inelastic Lepton-Nucleon Scattering
Latest results on structure functions, as available at the Lepton-Photon
Symposium 1999, are presented. This report focusses on three experimental
areas: new structure function measurements, in particular from HERA at low x
and high Q2; results on light and heavy flavour densities; determinations of
the gluon distribution and of alpha_s. As the talk was delivered at a historic
moment and place, a few remarks were added recalling the exciting past and
looking into the promising future of deep inelastic scattering.Comment: 27 pages, latex, 15 figures, Talk at Lepton-Photon Symposium,
Stanford, August 199
Small x Behavior of Parton Distributions from the Observed Froissart Energy Dependence of the Deep Inelastic Scattering Cross Section
We fit the reduced cross section for deep-inelastic electron scattering data
to a three parameter ln^2 s fit, A + beta ln^2 (s/s_0), where s= [Q^2/x] (1-x)
+ m^2, and Q^2 is the virtuality of the exchanged photon. Over a wide range in
Q^2 (0.11 < Q^2 < 1200 GeV^2) all of the fits satisfy the logarithmic energy
dependence of the Froissart bound. We can use these results to extrapolate to
very large energies and hence to very small values of Bjorken x -- well beyond
the range accessible experimentally. As Q^2 --> infinity, the structure
function F_2^p(x, Q^2) exhibits Bjorken scaling, within experimental errors. We
obtain new constraints on the behavior of quark and antiquark distribution
functions at small x.Comment: 10 pages, 2 figure
Strings on the deformed T^{1,1}: giant magnon and single spike solutions
In this paper we find giant magnon and single spike string solutions in a
sector of the gamma-deformed conifold. We examine the dispersion relations and
find a behavior analogous to the undeformed case. The transcendental functional
relations between the conserved charges are shifted by certain gamma-dependent
term. The latter is proportional to the total momentum and thus qualitatively
different from known cases.Comment: 35 pages, no figure
Cascading Quivers from Decaying D-branes
We use an argument analogous to that of Kachru, Pearson and Verlinde to argue
that cascades in L^{a,b,c} quiver gauge theories always preserve the form of
the quiver, and that all gauge groups drop at each step by the number M of
fractional branes. In particular, we demonstrate that an NS5-brane that sweeps
out the S^3 of the base of L^{a,b,c} destroys M D3-branes.Comment: 11 pages, 1 figure; v2: references adde
Protein kinase CK2 is widely expressed in follicular, Burkitt and diffuse large B-cell lymphomas and propels malignant B-cell growth.
Serine-threonine kinase CK2 is highly expressed and pivotal for survival and proliferation in multiple myeloma, chronic lymphocytic leukemia and mantle cell lymphoma. Here, we investigated the expression of \u3b1 catalytic and \u3b2 regulatory CK2 subunits by immunohistochemistry in 57 follicular (FL), 18 Burkitt (BL), 52 diffuse large B-cell (DLBCL) non-Hodgkin lymphomas (NHL) and in normal reactive follicles. In silico evaluation of available Gene Expression Profile (GEP) data sets from patients and Western blot (WB) analysis in NHL cell-lines were also performed. Moreover, the novel, clinical-grade, ATP-competitive CK2-inhibitor CX-4945 (Silmitasertib) was assayed on lymphoma cells. CK2 was detected in 98.4% of cases with a trend towards a stronger CK2\u3b1 immunostain in BL compared to FL and DLBCL. No significant differences were observed between Germinal Center B (GCB) and non-GCB DLBCL types. GEP data and WB confirmed elevated CK2 mRNA and protein levels as well as active phosphorylation of specific targets in NHL cells. CX-4945 caused a dose-dependent growth-arresting effect on GCB, non-GCB DLBCL and BL cell-lines and it efficiently shut off phosphorylation of NF-\u3baB RelA and CDC37 on CK2 target sites. Thus, CK2 is highly expressed and could represent a suitable therapeutic target in BL, FL and DLBCL NHL
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