31,026 research outputs found
On Self-Organized Criticality and Synchronization in Lattice Models of Coupled Dynamical Systems
Lattice models of coupled dynamical systems lead to a variety of complex
behaviors. Between the individual motion of independent units and the
collective behavior of members of a population evolving synchronously, there
exist more complicated attractors. In some cases, these states are identified
with self-organized critical phenomena. In other situations, with
clusterization or phase-locking. The conditions leading to such different
behaviors in models of integrate-and-fire oscillators and stick-slip processes
are reviewed.Comment: 41 pages. Plain LaTeX. Style included in main file. To appear as an
invited review in Int. J. Modern Physics B. Needs eps
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VLSI design of the tiny RISC microprocessor
This report describes the Tiny RISC microprocessor designed at UC Irvine. Tiny RISC is a 16-bit microprocessor and has a RISC-style architecture. The chip was fabricated by MOSIS [1] in a 2ÎĽm n-well CMOS technology. The processor has a cycle time of 70 ns
Investigation of the shear-mechanical and dielectric relaxation processes in two mono-alcohols close to the glass transition
Shear-mechanical and dielectric measurements on the two monohydroxy
(mono-alcohol) molecular glass formers 2-ethyl-1-hexanol and 2-butanol close to
the glass transition temperature are presented. The shear-mechanical data are
obtained using the piezoelectric shear-modulus gauge method covering
frequencies from 1mHz to 10kHz. The shear-mechanical relaxation spectra show
two processes, which follow the typical scenario of a structural (alpha)
relaxation and an additional (Johari-Goldstein) beta relaxation. The dielectric
relaxation spectra are dominated by a Debye-type peak with an additional
non-Debye peak visible. This Debye-type relaxation is a common feature peculiar
to mono-alcohols. The time scale of the non-Debye dielectric relaxation process
is shown to correspond to the mechanical structural (alpha) relaxation.
Glass-transition temperatures and fragilities are reported based on the
mechanical alpha relaxation and the dielectric Debye-type process, showing that
the two glass-transition temperatures differ by approximately 10K and that the
fragility based on the Debye-type process is a factor of two smaller than the
structural fragility. If a mechanical signature of the Debye-type relaxation
exists in these liquids, its relaxation strength is at most 1% and 3% of the
full relaxation strength of 2-butanol and 2-ethyl-1-hexanol respectively. These
findings support the notion that it is the non-Debye dielectric relaxation
process that corresponds to the structural alpha relaxation in the liquid.Comment: 8 pages, 6 figures. Minor corrections, updated figures, more
dielectric data show
Absence of an embryonic stem cell DNA methylation signature in human cancer.
BackgroundDifferentiated cells that arise from stem cells in early development contain DNA methylation features that provide a memory trace of their fetal cell origin (FCO). The FCO signature was developed to estimate the proportion of cells in a mixture of cell types that are of fetal origin and are reminiscent of embryonic stem cell lineage. Here we implemented the FCO signature estimation method to compare the fraction of cells with the FCO signature in tumor tissues and their corresponding nontumor normal tissues.MethodsWe applied our FCO algorithm to discovery data sets obtained from The Cancer Genome Atlas (TCGA) and replication data sets obtained from the Gene Expression Omnibus (GEO) data repository. Wilcoxon rank sum tests, linear regression models with adjustments for potential confounders and non-parametric randomization-based tests were used to test the association of FCO proportion between tumor tissues and nontumor normal tissues. P-values of < 0.05 were considered statistically significant.ResultsAcross 20 different tumor types we observed a consistently lower FCO signature in tumor tissues compared with nontumor normal tissues, with 18 observed to have significantly lower FCO fractions in tumor tissue (total n = 6,795 tumor, n = 922 nontumor, P < 0.05). We replicated our findings in 15 tumor types using data from independent subjects in 15 publicly available data sets (total n = 740 tumor, n = 424 nontumor, P < 0.05).ConclusionsThe results suggest that cancer development itself is substantially devoid of recapitulation of normal embryologic processes. Our results emphasize the distinction between DNA methylation in normal tightly regulated stem cell driven differentiation and cancer stem cell reprogramming that involves altered methylation in the service of great cell heterogeneity and plasticity
77Se NMR Investigation of the K(x)Fe(2-y)Se(2) High Tc Superconductor (Tc=33K)
We report a comprehensive 77Se NMR study of the structural, magnetic, and
superconducting properties of a single crystalline sample of the newly
discovered FeSe-based high temperature superconductor K(x)Fe(2-y)Se(2) (Tc=33K)
in a broad temperature range up to 290 K. We will compare our results with
those reported for FeSe (Tc=9K) and FeAs-based high Tc systems.Comment: Final versio
The Electronic Correlation Strength of Pu
An electronic quantity, the correlation strength, is defined as a necessary
step for understanding the properties and trends in strongly correlated
electronic materials. As a test case, this is applied to the different phases
of elemental Pu. Within the GW approximation we have surprisingly found a
"universal" scaling relationship, where the f-electron bandwidth reduction due
to correlation effects is shown to depend only on the local density
approximation bandwidth and is otherwise independent of crystal structure and
lattice constant.Comment: 7 pages, 4 figures, This version of the paper has been revised to add
additional background informatio
Finiteness and Dual Variables for Lorentzian Spin Foam Models
We describe here some new results concerning the Lorentzian Barrett-Crane
model, a well-known spin foam formulation of quantum gravity. Generalizing an
existing finiteness result, we provide a concise proof of finiteness of the
partition function associated to all non-degenerate triangulations of
4-manifolds and for a class of degenerate triangulations not previously shown.
This is accomplished by a suitable re-factoring and re-ordering of integration,
through which a large set of variables can be eliminated. The resulting
formulation can be interpreted as a ``dual variables'' model that uses
hyperboloid variables associated to spin foam edges in place of representation
variables associated to faces. We outline how this method may also be useful
for numerical computations, which have so far proven to be very challenging for
Lorentzian spin foam models.Comment: 15 pages, 1 figur
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