38,488 research outputs found
Robust variable selection in partially varying coefficient single-index model
By combining basis function approximations and smoothly clipped absolute deviation (SCAD) penalty, this paper proposes a robust variable selection procedure for a partially varying coefficient single-index model based on modal regression. The proposed procedure simultaneously selects significant variables in the parametric components and the nonparametric components. With appropriate selection of the tuning parameters, we establish the theoretical properties of our procedure, including consistency in variable selection and the oracle property in estimation. Furthermore, we also discuss the bandwidth selection and propose a modified expectation-maximization (EM)-type algorithm for the proposed estimation procedure. The finite sample properties of the proposed estimators are illustrated by some simulation examples.The research of Zhu is partially supported by National Natural Science Foundation of China (NNSFC) under Grants 71171075, 71221001 and 71031004. The research of Yu is supported by NNSFC under Grant 11261048
Role of noncoding RNA in vascular remodelling
Purpose of review: Noncoding RNAs (ncRNAs), such as microRNAs (miRNAs) and long noncoding RNAs (lncRNAs) are becoming fundamentally important in the pathophysiology relating to injury-induced vascular remodelling. We highlight recent studies that demonstrate the involvement of ncRNAs in vein graft disease, in in-stent restenosis and in pulmonary arterial hypertension, with a particular focus on endothelial cell and vascular smooth muscle cell function. We also briefly discuss the emerging role of exosomal-derived ncRNAs and how this mechanism impacts on vascular function.
Recent findings: ncRNAs have been described as novel regulators in the pathophysiology of vascular injury, inflammation, and vessel wall remodelling. In particular, several studies have demonstrated that manipulation of miRNAs can reduce the burden of pathological vascular remodelling. Such studies have also shown that exosomal miRNA-mediated, cell-to-cell communication between endothelial cells and vascular smooth muscle cells is critical in the disease process. In addition to miRNAs, lncRNAs are emerging as regulators of vascular function in health and disease. Although lncRNAs are complex in both their sheer numbers and mechanisms of action, identifying their contribution to vascular disease is essential.
Summary: Given the important roles of ncRNAs in vascular injury and remodelling together will their capacity for cell-to-cell communication, manipulating ncRNA might provide novel therapeutic interventions
Effect of weak measurement on entanglement distribution over noisy channels
Being able to implement effective entanglement distribution in noisy
environments is a key step towards practical quantum communication, and
long-term efforts have been made on the development of it. Recently, it has
been found that the null-result weak measurement (NRWM) can be used to enhance
probabilistically the entanglement of a single copy of amplitude-damped
entangled state. This paper investigates remote distributions of bipartite and
multipartite entangled states in the amplitudedamping environment by combining
NRWMs and entanglement distillation protocols (EDPs). We show that the NRWM has
no positive effect on the distribution of bipartite maximally entangled states
and multipartite Greenberger-Horne-Zeilinger states, although it is able to
increase the amount of entanglement of each source state (noisy entangled
state) of EDPs with a certain probability. However, we find that the NRWM would
contribute to remote distributions of multipartite W states. We demonstrate
that the NRWM can not only reduce the fidelity thresholds for distillability of
decohered W states, but also raise the distillation efficiencies of W states.
Our results suggest a new idea for quantifying the ability of a local filtering
operation in protecting entanglement from decoherence.Comment: 15 pages, 9 figures. Minor revision has been mad
Simulation-based evaluation of defuzzification-based approaches to fuzzy multi-attribute decision making
This paper presents a simulation-based study to evaluate the performance of 12 defuzzification-based approaches for solving the general fuzzy multiattribute decision-making (MADM) problem requiring cardinal ranking of decision alternatives. These approaches are generated based on six defuzzification methods in conjunction with the simple additive weighting (SAW) method and the technique for order preference by similarity to the ideal solution method. The consistency and effectiveness of these approaches are examined in terms of four new objective performance measures, which are based on five evaluation indexes. The Simulation result shows that the approaches, which are capable of using all the available information on fuzzy numbers, effectively in the defuzzification process, produce more consistent ranking outcomes. In particular, the SAW method with the degree of dominance defuzzification is proved to be the overall best performed approach, which is, followed by the SAW method with the area center defuzzification. These findings are of practical significance in real-world settings where the selection of the defuzzification-based approaches is required in solving the general fuzzy MADM problems under specific decision contexts
Flux rope, hyperbolic flux tube, and late EUV phases in a non-eruptive circular-ribbon flare
We present a detailed study of a confined circular flare dynamics associated
with 3 UV late phases in order to understand more precisely which topological
elements are present and how they constrain the dynamics of the flare. We
perform a non-linear force free field extrapolation of the confined flare
observed with the HMI and AIA instruments onboard SDO. From the 3D magnetic
field we compute the squashing factor and we analyse its distribution.
Conjointly, we analyse the AIA EUV light curves and images in order to identify
the post-flare loops, their temporal and thermal evolution. By combining both
analysis we are able to propose a detailed scenario that explains the dynamics
of the flare. Our topological analysis shows that in addition to a null-point
topology with the fan separatrix, the spine lines and its surrounding
Quasi-Separatix Layers halo (typical for a circular flare), a flux rope and its
hyperbolic flux tube (HFT) are enclosed below the null. By comparing the
magnetic field topology and the EUV post-flare loops we obtain an almost
perfect match 1) between the footpoints of the separatrices and the EUV
1600~\AA{} ribbons and 2) between the HFT's field line footpoints and bright
spots observed inside the circular ribbons. We showed, for the first time in a
confined flare, that magnetic reconnection occured initially at the HFT, below
the flux rope. Reconnection at the null point between the flux rope and the
overlying field is only initiated in a second phase. In addition, we showed
that the EUV late phase observed after the main flare episode are caused by the
cooling loops of different length which have all reconnected at the null point
during the impulsive phase.Comment: Astronomy & Astrophysics, in pres
Circular quantum secret sharing
A circular quantum secret sharing protocol is proposed, which is useful and
efficient when one of the parties of secret sharing is remote to the others who
are in adjacent, especially the parties are more than three. We describe the
process of this protocol and discuss its security when the quantum information
carrying is polarized single photons running circularly. It will be shown that
entanglement is not necessary for quantum secret sharing. Moreover, the
theoretic efficiency is improved to approach 100% as almost all the instances
can be used for generating the private key, and each photon can carry one bit
of information without quantum storage. It is straightforwardly to utilize this
topological structure to complete quantum secret sharing with multi-level
two-particle entanglement in high capacity securely.Comment: 7 pages, 2 figure
Quantum secure direct communication network with superdense coding and decoy photons
A quantum secure direct communication network scheme is proposed with quantum
superdense coding and decoy photons. The servers on a passive optical network
prepare and measure the quantum signal, i.e., a sequence of the -dimensional
Bell states. After confirming the security of the photons received from the
receiver, the sender codes his secret message on them directly. For preventing
a dishonest server from eavesdropping, some decoy photons prepared by measuring
one photon in the Bell states are used to replace some original photons. One of
the users on the network can communicate any other one. This scheme has the
advantage of high capacity, and it is more convenient than others as only a
sequence of photons is transmitted in quantum line.Comment: 6 pages, 2 figur
Superconductor-Nanowire Devices from Tunneling to the Multichannel Regime: Zero-Bias Oscillations and Magnetoconductance Crossover
We present transport measurements in superconductor-nanowire devices with a
gated constriction forming a quantum point contact. Zero-bias features in
tunneling spectroscopy appear at finite magnetic fields, and oscillate in
amplitude and split away from zero bias as a function of magnetic field and
gate voltage. A crossover in magnetoconductance is observed: Magnetic fields
above ~ 0.5 T enhance conductance in the low-conductance (tunneling) regime but
suppress conductance in the high-conductance (multichannel) regime. We consider
these results in the context of Majorana zero modes as well as alternatives,
including Kondo effect and analogs of 0.7 structure in a disordered nanowire.Comment: Supplemental Material here:
https://dl.dropbox.com/u/1742676/Churchill_Supplemental.pd
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