Joint Optimal Design and Operation of Hybrid Energy Storage Systems

The wide range of performance characteristics of storage technologies motivates the use of a hybrid energy storage systems (HESS) that combines the best features of multiple technologies. However, HESS design is complex, in that it involves the choice of storage technologies, the sizing of each storage element, and deciding when to charge and discharge each underlying storage element (the operating strategy.We formulate the problem of jointly optimizing the sizing and the operating strategy of an HESS that can be used for a large class of applications and storage technologies. Instead of a single set of storage element sizes, our approach determines the Pareto-optimal frontier of the sizes of the storage elements along with the corresponding optimal operating strategy. Thus, as long as the performance objective of a storage application (such as an off-grid microgrid) can be expressed as a linear combination of the underlying storage sizes, the optimal vector of storage sizes falls somewhere on this frontier. We present two case studies to illustrate our approach, demonstrating that a single storage technology is sometimes inadequate to meet application requirements, unlike an HESS designed using our approach. We also find simple, near-optimal, and practical operating strategies for these case studies, which allows us to gain several new engineering insights

Metal-free tandem rearrangement/lactonization: Access to 3,3-disubstituted benzofuran-2-(3H)-ones

A novel metal‐free synthesis of 3,3‐disubstituted benzofuran‐2(3H)‐ones from the reaction between α‐aryl‐α‐diazoacetates and triarylboranes is presented. Initially, triarylboranes were successfully investigated in α‐arylations of α‐diazoacetates, however in the presence of an ortho‐heteroatom substituent the boron enolate intermediate undergoes an intramolecular rearrangement to form a quaternary center. The intermediate cyclizes affording valuable 3,3‐disubstituted benzofuranones in good yield

Constraints on small-scale cosmological perturbations from gamma-ray searches for dark matter

Events like inflation or phase transitions can produce large density perturbations on very small scales in the early Universe. Probes of small scales are therefore useful for e.g. discriminating between inflationary models. Until recently, the only such constraint came from non-observation of primordial black holes (PBHs), associated with the largest perturbations. Moderate-amplitude perturbations can collapse shortly after matter-radiation equality to form ultracompact minihalos (UCMHs) of dark matter, in far greater abundance than PBHs. If dark matter self-annihilates, UCMHs become excellent targets for indirect detection. Here we discuss the gamma-ray fluxes expected from UCMHs, the prospects of observing them with gamma-ray telescopes, and limits upon the primordial power spectrum derived from their non-observation by the Fermi Large Area Space Telescope.Comment: 4 pages, 3 figures. To appear in J Phys Conf Series (Proceedings of TAUP 2011, Munich

Pattern Of Reduced Functional Connectivity And Structural Abnormalities In Parkinson's Disease: An Exploratory Study

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)MRI brain changes in Parkinson's disease (PD) are controversial. Objectives: We aimed to describe structural and functional changes in PD. Methods: Sixty-six patients with PD (57.94 +/- 10.25 years) diagnosed according to the UK Brain Bank criteria were included. We performed a whole brain analysis using voxel-based morphometry (VBM-SPM 8 software), cortical thickness (CT) using CIVET, and resting-state fMRI using the Neuroimaging Analysis Kit software to compare patients and controls. For VBM and CT we classified subjects into three groups according to disease severity: mild PD [Hoehn and Yahr scale (HY) 1-1.5], moderate PD (HY 2-2.5), and severe PD (HY 3-5). Results: We observed gray matter atrophy in the insula and inferior frontal gyrus in the moderate PD and in the insula, frontal gyrus, putamen, cingulated, and paracingulate gyri in the severe groups. In the CT analysis, in mild PD, cortical thinning was restricted to the superior temporal gyrus, gyrus rectus, and olfactory cortex; in the moderate group, the postcentral gyrus, supplementary motor area, and inferior frontal gyrus were also affected; in the severe PD, areas such as the precentral and postentral gyrus, temporal pole, fusiform, and occipital gyrus had reduced cortical thinning. We observed altered connectivity at the default mode, visual, sensorimotor, and cerebellar networks. Conclusion: Subjects with mild symptoms already have cortical involvement; however, further cerebral involvement seems to follow Braak's proposed mechanism. Similar regions are affected both structurally and functionally. We believe the combination of different MRI techniques may be useful in evaluating progressive brain involvement and they may eventually be used as surrogate markers of disease progression.7FAPESP (Sao Paulo Research Foundation) [2012/05286-7, 2011/19958-4, 2013/03358-3]CNPq [74873/2010-2]FAPESPIpsenCNPq, BRAZILFAPESP, BRAZILFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP

Designing procedure execution tools with emerging technologies for future astronauts

NASA’s human spaceflight efforts are moving towards long-duration exploration missions requiring asynchronous communication between onboard crew and an increasingly remote ground support. In current missions aboard the International Space Station, there is a near real-time communication loop between Mission Control Center and astronauts. This communication is essential today to support operations, maintenance, and science requirements onboard, without which many tasks would no longer be feasible. As NASA takes the next leap into a new era of human space exploration, new methods and tools compensating for the lack of continuous, real-time communication must be explored. The Human-Computer Interaction Group at NASA Ames Research Center has been investigating emerging technologies and their applicability to increase crew autonomy in missions beyond low Earth orbit. Interactions using augmented reality and the Internet of Things have been researched as possibilities to facilitate usability within procedure execution operations. This paper outlines four research efforts that included technology demonstrations and usability studies with prototype procedure tools implementing emerging technologies. The studies address habitat feedback integration, analogous procedure testing, task completion management, and crew training. Through these technology demonstrations and usability studies, we find that low-to medium-fidelity prototypes, evaluated early in the design process, are both effective for garnering stakeholder buy-in and developing requirements for future systems. In this paper, we present the findings of the usability studies for each project and discuss ways in which these emerging technologies can be integrated into future human spaceflight operations

Psychosocial Screening in Disorders/Differences of Sex Development: Psychometric Evaluation of the Psychosocial Assessment Tool

© 2019 S. Karger AG, Basel. Background/Aims: Utilization of a psychosocial screener to identify families affected by a disorder/difference of sex development (DSD) and at risk for adjustment challenges may facilitate efficient use of team resources to optimize care. The Psychosocial Assessment Tool (PAT) has been used in other pediatric conditions. The current study explored the reliability and validity of the PAT (modified for use within the DSD population; PAT-DSD). Methods: Participants were 197 families enrolled in the DSD-Translational Research Network (DSD-TRN) who completed a PAT-DSD during a DSD clinic visit. Psychosocial data were extracted from the DSD-TRN clinical registry. Internal reliability of the PAT-DSD was tested using the Kuder-Richardson-20 coefficient. Validity was examined by exploring the correlation of the PAT-DSD with other measures of caregiver distress and child emotional-behavioral functioning. Results: One-third of families demonstrated psychosocial risk (27.9% Targeted and 6.1% Clinical level of risk). Internal reliability of the PAT-DSD Total score was high (α = 0.86); 4 of 8 subscales met acceptable internal reliability. A priori predicted relationships between the PAT-DSD and other psychosocial measures were supported. The PAT-DSD Total score related to measures of caregiver distress (r = 0.40, p \u3c 0.001) and to both caregiver-reported and patient self-reported behavioral problems (r = 0.61, p \u3c 0.00; r = 0.37, p \u3c 0.05). Conclusions: This study provides evidence for the reliability and validity of the PAT-DSD. Given variability in the internal reliability across subscales, this measure is best used to screen for overall family risk, rather than to assess specific psychosocial concerns

Influence of Fiber-Reinforced Polymer Sheets on the Constitutive Relationships of Reinforced Concrete Elements

Fiber-reinforced polymer (FRP) started to find its way as an economical alternative material in civil engineering in the early 1970s. The behavior and failure modes for FRP composite structures were studied through extensive experimental and analytical investigations. Although research related to the flexural behavior of FRP-strengthened elements has reached a mature phase, studies related to FRP shear strengthening are less advanced. In all proposed models to predict shear capacity, the constitutive behaviors of concrete and FRP are described independently. The true behavior, however, should account for the high level of interaction between the two materials. Constitutive relations for FRP-strengthened reinforced concrete (RC) elements should provide a better understanding of the shear behavior of the composite structure. To generate these relations, large-scale tests of a series of FRP-strengthened RC panel elements subjected to pure shear were conducted. This paper presents the results of the test program and the calibration of the parameters of the constitutive model. These constitutive laws could easily be implemented in finite-element models to predict the behavior of externally bonded FRP-strengthened beams. The focus in this work is on elements failing because of concrete crushing and not because of FRP debonding. The newly developed model provides a good level of accuracy when compared with experimental results