The 8-13 micron observations of Titan

Narrow band observations of Titan at selected wavelengths in the 8-13 micron range show evidence for a strong temperature inversion and the existence of at least one more spectroscopically active component in the atmosphere in addition to H2 and CH4

A Look-Ahead Feature - Sow Stalls for Indiviudal Feeding

Overfeeding sows and gilts during gestation is a common mismanagement practice. Here\u27s how concrete stalls were built for individual feeding to assure a minimum, but adequate, amount of feed for each animal

COMPTEL solar flare observations

COMPTEL as part of a solar target of opportunity campaign observed the sun during the period of high solar activity from 7-15 Jun. 1991. Major flares were observed on 9 and 11 Jun. Although both flares were large GOES events (greater than or = X10), they were not extraordinary in terms of gamma-ray emission. Only the decay phase of the 15 Jun. flare was observed by COMPTEL. We report the preliminary analysis of data from these flares, including the first spectroscopic measurement of solar flare neutrons. The deuterium formation line at 2.223 MeV was present in both events and for at least the 9 Jun. event, was comparable to the flux in the nuclear line region of 4-8 MeV, consistent with Solar-Maximum Mission (SSM) Observations. A clear neutron signal was present in the flare of 9 Jun. with the spectrum extending up to 80 MeV and consistent in time with the emission of gamma-rays, confirming the utility of COMPTEL in measuring the solar neutron flux at low energies. The neutron flux below 100 MeV appears to be lower than that of the 3 Jun. 1982 flare by more than an order of magnitude. The neutron signal of the 11 Jun. event is under study. Severe dead time effects resulting from the intense thermal x-rays require significant corrections to the measured flux which increase the magnitude of the associated systematic uncertainties

Cellular Uptake and Internalization of Hyaluronan-based Doxorubicin and Cisplatin Conjugates

Background Hyaluronan (HA) is a ligand for the CD44 receptor which is crucial to cancer cell proliferation and metastasis. High levels of CD44 expression in many cancers have encouraged the development of HA-based carriers for anti-cancer therapeutics. Purpose The objective of this study was to determine whether HA conjugation of anticancer drugs impacts CD44-specific HA-drug uptake and disposition by human head and neck cancer cells. Methods The internalization and cellular disposition of hyaluronan-doxorubicin (HA-DOX), hyaluronan-cisplatin (HA-Pt), and hyaluronan-cyanine7 (HA-Cy7) conjugates were investigated by inhibiting endocytosis pathways, and by inhibiting the CD44–mediated internalization pathways that are known to mediate hyaluronan uptake in vitro. Results Cellular internalization of HA was regulated by CD44 receptors. In mouse xenografts, HA conjugation significantly enhanced tumor cell uptake compared to unconjugated drug. Discussion The results suggested that the main mechanism of HA-based conjugate uptake may be active transport via CD44 in conjunction with a clathrin–dependent endocytic pathway. Other HA receptors, hyaluronan–mediated motility receptor (RHAMM) and lymphatic vessel endothelial hyaluronan receptor (LYVE-1), did not play a significant role in conjugate uptake. Conclusions HA conjugation significantly increased CD44 mediated drug uptake and extended the residence time of drugs in tumor cells

Wildfire, climate, and perceptions in northeast Oregon

Wildfire poses a rising threat in the western USA, fueled by synergies between historical fire suppression, changing land use, insects and disease, and shifts toward a drier, warmer climate. The rugged landscapes of northeast Oregon, with their historically forest- and resource-based economies, have been one of the areas affected. A 2011 survey found area residents highly concerned about fire and insect threats, but not about climate change. In 2014 we conducted a second survey that, to explore this apparent disconnect, included questions about past and future summertime (fire season) temperatures. Although regional temperatures have warmed in recent decades at twice the global rate, accompanied by increasing dryness and fire risks, the warming itself is recognized by only 40 % of our respondents. Awareness of recent warming proves unrelated to individual characteristics that might indicate experience on the land: old-timer versus newcomer status, year-round versus seasonal residence, and ownership of forested land. Perceptions of past warming and expectations of future warming are more common among younger respondents and less common among Tea Party supporters. The best-educated partisans stand farthest apart. Perceptions about local temperatures that are important for adaptation planning thus follow ideological patterns similar to beliefs about global climate change

The Case of Professor James W. Silver

Article about attempts by the legislature and board of trustees to try and remove James Silver from his job at the University of Mississippi; Source: AAUP Bulletinhttps://egrove.olemiss.edu/jws_clip/1030/thumbnail.jp

Does it matter if people think climate change is human caused?

There is a growing consensus that climate is changing, but beliefs about the causal factors vary widely among the general public. Current research shows that such causal beliefs are strongly influenced by cultural, political, and identity-driven views. We examined the influence that local perceptions have on the acceptance of basic facts about climate change. We also examined the connection to wildfire by local people. Two recent telephone surveys found that 37% (in 2011) and 46% (in 2014) of eastern Oregon (USA) respondents accept the scientific consensus that human activities are now changing the climate. Although most do not agree with that consensus, large majorities (85–86%) do agree that climate is changing, whether by natural or human causes. Acceptance of anthropogenic climate change generally divides along political party lines, but acceptance of climate change more generally, and concerns about wildfire, transcend political divisions. Support for active forest management to reduce wildfire risks is strong in this region, and restoration treatments could be critical to the resilience of both communities and ecosystems. Although these immediate steps involve adaptations to a changing climate, they can be motivated without necessarily invoking human-caused climate change, a divisive concept among local landowners

Forest Views: Shifting Attitudes Toward the Environment in Northeast Oregon

This brief reports on a telephone survey conducted in fall 2014 as part of the ongoing Communities and Forests in Oregon (CAFOR) project. CAFOR focuses on seven counties in the Blue Mountains of northeast Oregon (Baker, Crook, Grant, Umatilla, Union, Wallowa, and Wheeler), where the landscape and local livelihoods are changing in interconnected ways. In an effort to inform policy development around natural resource management, the study seeks to understand how public perceptions of climate change and forest management intersect. Authors Angela Boag, Joel Hartter, Lawrence Hamilton, Forrest Stevens, Mark Ducey, Michael Palace, Nils Christoffersen, and Paul Oester report that 65 percent of those surveyed believe that forests are less healthy than they were twenty years ago. Approximately half of residents support increased user fees to improve forest health on federal land, and a majority believes that climate change is happening, although opinion is split between those who believe it is human-caused and those who believe it is caused by natural forces. The authors conclude that innovative economic and policy solutions are needed across the Inland West to help people and forests regain a strong and productive relationship that both supports livelihoods and sustains working landscapes