390 research outputs found
The Counter Narrative: Reframing Success of High Achieving Black and Latino Males in Los Angeles County
This report highlights young men who are the products of high expectations. We take time to shine a spotlight on the resilient, intelligent, and caring young men across Los Angeles County. This report takes an unapologetic stance in stating that these young men who are thriving in their homes, taking on leadership roles in their schools, and making a difference in their communities. This report is not intended to be full of the doom and gloom about what is wrong with young Black and Latino men. To the contrary, we take the time to center their voices, hear their stories, and listen to their takeaways about how they have accomplished what they are doing and the recommendations that they offer on how to support other Black and Latino young men just like them
The White-hat Bot: A Novel Botnet Defense Strategy
Botnets are a threat to computer systems and users around the world. Botmasters can range from annoying spam email propagators to nefarious criminals. These criminals attempt to take down networks or web servers through distributed denial-of-service attacks, to steal corporate secrets, or to launder money from individuals or corporations. As the number and severity of successful botnet attacks rise, computer security experts need to develop better early-detection and removal techniques to protect computer networks and individual computer users from these very real threats. I will define botnets and describe some of their common purposes and current uses. Next, I will reveal some of the techniques currently used by software security professionals to combat this problem. Finally I will provide a novel defensive strategy, the White-hat Bot (WHB), with documented experiments and results that may prove useful in the defense against botnets in the future
The Role of Integrin-associated Protein “PINCH” in Kidney Development
PINCH (a particularly interesting new cysteine-histidine-rich protein) is a protein that binds with Integrin-linked kinase and Parvin, to form an IPP complex. This complex is formed only when integrin molecules are activated upon interaction with the basement membrane. The IPP complex then acts as a platform for other proteins to come together and regulate cell signaling to and from the extracellular matrix (ECM). This allows for various cellular activities to progress like cell adhesion, migration, proliferation, etc. There are two types of PINCH proteins, PINCH-1 and PINCH-2. Studies from our group have shown that the lack of PINCH-1 in the kidney results in a branching phenotype and smaller kidneys in mice. The cells showed diminished potential to adhere, migrate and proliferate. There is no significant difference in phenotype when PINCH-2 is deleted.
In the present study, we use conditional double knockout mice and cells in culture to look at the additive effects of the two PINCH proteins. Stained kidney cross sections will be analyzed and the PINCH null cells will be used in cell adhesion and migration studies.
We have preliminary data to show that the deletion of both PINCH-1 and PINCH-2 genes results in a severe developmental phenotype in mouse kidney and corroborates in vitro studies
On the Detection of Supermassive Primordial Stars. II. Blue Supergiants
Supermassive primordial stars in hot, atomically-cooling haloes at
15 - 20 may have given birth to the first quasars in the universe. Most
simulations of these rapidly accreting stars suggest that they are red, cool
hypergiants, but more recent models indicate that some may have been bluer and
hotter, with surface temperatures of 20,000 - 40,000 K. These stars have
spectral features that are quite distinct from those of cooler stars and may
have different detection limits in the near infrared (NIR) today. Here, we
present spectra and AB magnitudes for hot, blue supermassive primordial stars
calculated with the TLUSTY and CLOUDY codes. We find that photometric
detections of these stars by the James Webb Space Telescope (JWST) will be
limited to 10 - 12, lower redshifts than those at which red stars
can be found, because of quenching by their accretion envelopes. With moderate
gravitational lensing, Euclid and the Wide-Field Infrared Space Telescope
(WFIRST) could detect blue supermassive stars out to similar redshifts in
wide-field surveys.Comment: 9 pages, 5 figures, accepted by MNRA
The decision to install flue gas desulphurisation on Medupi Power Station: identification of environmental criteria contributing to the decision making process
Survival of society has always been dependent on ensuring that a balance is
continually maintained between the variables of social needs, resources and the
environment. The difficulty is that these three elements are more often than not
in conflict with each other. Arguably without such conflicts environmental
decision making would be far simpler in the knowledge that the potential solution,
although not pleasing everyone would be capable of responding to a range of
ecological and economic concerns. Environmental decision making requires a
structured holistic approach that allows for the evaluation of alternative solutions
against an array of often conflicting objectives, although no specific decision
making structure is advocated multi criteria objective decision making provides a
means to achieve such ends. The methodology provides for the identification of
all objectives which are then used to evaluate alternative scenarios or solutions
against.
The following research report seeks to identify the environmental criteria that
would need to be considered as part of a multi-criteria decision making structure.
The report highlights the complexities and often conflicting elements that exist
even within the narrow scope of environmental objectives. All discussions are
made with specific reference to Eskom’s requirement to comply to future air
quality legislation and the potential requirement to install flue gas
desulphurisation technologies on its Medupi Power Station. Legislative,
technological, water and air quality issues are identified and explored as to how
they should be evaluated as part of the overall environmental decision making
criteria. Through the identification of the environmental criteria it is hinted that
Eskoms narrow mandate of electricity production at the lowest cost could
potentially prevent the organisation of fully engaging in a holistic decision making
process
Bacterial Communities of Two Ubiquitous Great Barrier Reef Corals Reveals Both Site- and Species-Specificity of Common Bacterial Associates
Background: Coral-associated bacteria are increasingly considered to be important in coral health, and altered bacterial community structures have been linked to both coral disease and bleaching. Despite this, assessments of bacterial communities on corals rarely apply sufficient replication to adequately describe the natural variability. Replicated data such as these are crucial in determining potential roles of bacteria on coral
Pennsylvania Folklife Vol. 15, No. 4
• Amish Album • Look Back, Once! • The Pennsylvania Barn in the South: Part II • Folk Festival Program • Contributors to this Issue • Festival Highlights • Twenty Questions on Powwowing • Moon-Signs in Cumberland County • Reminiscences of Des Dumm Fattel • Notes and Documents: Two Documents from the First World War • The Dutch and Irish Colonies of Pennsylvaniahttps://digitalcommons.ursinus.edu/pafolklifemag/1024/thumbnail.jp
An Observationally-Derived Kick Distribution for Neutron Stars in Binary Systems
Understanding the natal kicks received by neutron stars (NSs) during
formation is a critical component of modelling the evolution of massive
binaries. Natal kicks are an integral input parameter for population synthesis
codes, and have implications for the formation of double NS systems and their
subsequent merger rates. However, many of the standard observational kick
distributions that are used are obtained from samples created only from
isolated NSs. Kick distributions derived in this way overestimate the intrinsic
NS kick distribution. For NSs in binaries, we can only directly estimate the
effect of the natal kick on the binary system, instead of the natal kick
received by the NS itself. Here, for the first time, we present a binary kick
distribution for NSs with low-mass companions. We compile a catalogue of 145
NSs in low-mass binaries with the best available constraints on proper motion,
distance, and systemic radial velocity. For each binary, we use a
three-dimensional approach to estimate its binary kick. We discuss the
implications of these kicks on system formation, and provide a parametric model
for the overall binary kick distribution, for use in future theoretical
modelling work. We compare our results with other work on isolated NSs and NSs
in binaries, finding that the NS kick distributions fit using only isolated
pulsars underestimate the fraction of NSs that receive low kicks. We discuss
the implications of our results on modelling double NS systems, and provide
suggestions on how to use our results in future theoretical works.Comment: Accepted for publication in MNRAS. 28 pages, 19 figures, 8 table
- …