Fourth annual Science in the House exhibition at the new parliament building

Members of Parliament, the House of Representatives and researchers were in attendance at the 4th annual Science in the House exhibition in the New Parliament Building in Valletta at noon of Thursday 24th September 2015. The event was inaugurated under the auspices of the Off ce of the Speaker by Ray Scicluna. Following comments by Prof. Alex Felice, speeches were presented by MPs Deborah Schembri and Claudio Grech. A few comments were made on behalf of the Faculty of Science by Prof. Emmanuel Sinagra to commemorate the 100th anniversary of the founding of the Faculty of Science at the University of Malta. The formal opening of the event concluded with enlightening words from the University Rector, Prof. Juanito Camilleri. The exhibition consisted of 12 posters representative of various research projects at the University of Malta from the Faculties of Science, Medicine and Surgery, Dental Surgery and Health Sciences. A commemorative poster was also dis played by the Faculty of Science to celebrate its 100th anniversary, which coincides with the centennial of Einstein's theory of relativity. Science in the House is organised by the Malta Chamber of Scientists, the University Research Trust (RIDT) and the Science in the City, European Researchers' Night consortium. Science in the City, European Researchers Night is mainly funded by the EU Marie Sklodowska-Curie Action of the Horizon 2020 (H2020) Programme. It is recognised by Europe for Festivals, Festivals for Europe (EFFE).peer-reviewe

The prisoner's right to vote and civic responsibility: Reaffirming the social contract?

Copyright © 2009 NAPOThis article considers the issue of the prisoner’s right to vote in the light of recent developments in law and policy. It critically reviews the purported justifications for disenfranchisement and argues that re-enfranchisement should be pursued on the grounds of both principle and policy

Weak signals in healthcare: The case study of the Mid-Staffordshire NHS Foundation Trust

Most organisational disasters have warning signals prior to the event occurring, which are increasingly appearing in accident reports. In the case of the Mid-Staffordshire Disaster, the disaster was not as a result of component failure or human error but rather an organisation that drifted into failure with precursory warning signals being ignored. It has been estimated that between 400 and 1200 patients died as a result of poor care between 2004 and 2009. The aim of this study was to identify the precursory signals and their rationalizations that occurred during this event. Qualitative document analysis was used to analyse the independent and public inquiry reports. Signals were present on numerous system levels. At a person level, there were cases of staff trying to make management aware of the problems, as well as the campaign “Cure the NHS” started by bereaved relatives. At an organisational level, examples of missed signals included the decrease in the trust’s star rating due to failure to meet targets, the NHS care regulator voicing concern regarding the unusually high death rates and auditors’ reports highlighting concerns regarding risk management. At an external level, examples included negative peer reviews from various external organizations

Proceedings of Science in the House

Celebrating its 5th anniversary, this year's Science in the House exhibition was a most memorable occasion. The event was held on Thursday 29th September at 11:00 am in the main foyer of the Parliament Building in Valletta. The event commenced with opening remarks from Prof. Alex Felice, chairman of the Science in the City/European Researchers' Night consortium followed by a distinguished list of speakers including Prof. Alfred Vella, Rector of the University of Malta, the Hon. Evarist Bartolo M.P., Minister for Education and Employment, and the Hon. Anglu Farrugia M.P., Speaker of the House of Representatives, Parliament of Malta. This year's event showcased a selection of research projects on neuroscience and brain research in addition to the regular compliment of posters from across various research disciplines. A set of four posters on the neuroscience theme presented research on the use of stereo-electroencephalography (EEG), the treatment of epilepsy with light, biochemical studies of autism and research related to depression, addition and epilepsy. Science in the House is organised by the Malta Chamber of Scientists, the RIDT and the Science in the City/European Researchers' Night consortium and part funded by the EU Marie Sklodowska-Curie Action of the Horizon 2020 (H2020) Programme.peer-reviewe

Bioactivity of common pesticidal plants on fall armyworm larvae (spodoptera frugiperda)

The fall armyworm (FAW), Spodoptera frugiperda (Lepidoptera: Noctuidae) is a recent invasive pest species that has successfully established across sub‐Saharan Africa where it continues to disrupt agriculture, particularly smallholder cereal production. Management of FAW in its native range in the Americas has led to the development of resistance to many commercial pesticides before its arrival in Africa. Pesticide use may therefore be ineffective for FAW control in Africa, so new and more sustainable approaches to pest management are required that can help reduce the impact of this exotic pest. Pesticidal plants provide an effective and established approach to pest management in African smallholder farming and recent research has shown that their use can be cost‐beneficial and sustainable. In order to optimize the use of botanical extracts for FAW control, we initially screened ten commonly used plant species. In laboratory trials, contact toxicity and feeding bioassays showed differential effects. Some plant species had little to no effect when compared to untreated controls; thus, only the five most promising plant species were selected for more detailed study. In contact toxicity tests, the highest larval mortality was obtained from Nicotiana tabacum (66%) and Lippia javanica (66%). Similarly, in a feeding bioassay L. javanica (62%) and N. tabacum (60%) exhibited high larval mortality at the highest concentration evaluated (10% w/v). Feeding deterrence was evaluated using glass‐fibre discs treated with plant extracts, which showed that Cymbopogon citratus (36%) and Azadirachta indica (20%) were the most potent feeding deterrents among the pesticidal plants evaluated. In a screenhouse experiment where living maize plants infested with fall armyworm larvae were treated with plant extracts, N. tabacum and L. javanica were the most potent species at reducing foliar damage compared to the untreated control whilst the synthetic pesticide chlorpyrifos was the most effective in reducing fall armyworm foliar damage. Further field trial evaluation is recommended, particularly involving smallholder maize fields to assess effectiveness across a range of contexts

Which doctors and with what problems contact a specialist service for doctors? A cross sectional investigation

Background: In the United Kingdom, specialist treatment and intervention services for doctors are underdeveloped. The MedNet programme, created in 1997 and funded by the London Deanery, aims to fill this gap by providing a self-referral, face-to-face, psychotherapeutic assessment service for doctors in London and South-East England. MedNet was designed to be a low-threshold service, targeting doctors without formal psychiatric problems. The aim of this study was to delineate the characteristics of doctors utilising the service, to describe their psychological morbidity, and to determine if early intervention is achieved. Methods: A cross-sectional study including all consecutive self-referred doctors (n = 121, 50% male) presenting in 2002–2004 was conducted. Measures included standardised and bespoke questionnaires both self-report and clinician completed. The multi-dimensional evaluation included: demographics, CORE (CORE-OM, CORE-Workplace and CORE-A) an instrument designed to evaluate the psychological difficulties of patients referred to outpatient services, Brief Symptom Inventory to quantify caseness and formal psychiatric illness, and Maslach Burnout Inventory. Results: The most prevalent presenting problems included depression, anxiety, interpersonal, self-esteem and work-related issues. However, only 9% of the cohort were identified as severely distressed psychiatrically using this measure. In approximately 50% of the sample, problems first presented in the preceding year. About 25% were on sick leave at the time of consultation, while 50% took little or no leave in the prior 12 months. A total of 42% were considered to be at some risk of suicide, with more than 25% considered to have a moderate to severe risk. There were no significant gender differences in type of morbidity, severity or days off sick. Conclusion: Doctors displayed high levels of distress as reflected in the significant proportion of those who were at some risk of suicide; however, low rates of severe psychiatric illness were detected. These findings suggest that MedNet clients represent both ends of the spectrum of severity, enabling early clinical engagement for a significant proportion of cases that is of importance both in terms of personal health and protecting patient care, and providing a timely intervention for those who are at risk, a group for whom rapid intervention services are in need and an area that requires further investigation in the UK

Copy Number Variants and Common Disorders: Filling the Gaps and Exploring Complexity in Genome-Wide Association Studies

Genome-wide association scans (GWASs) using single nucleotide polymorphisms (SNPs) have been completed successfully for several common disorders and have detected over 30 new associations. Considering the large sample sizes and genome-wide SNP coverage of the scans, one might have expected many of the common variants underpinning the genetic component of various disorders to have been identified by now. However, these studies have not evaluated the contribution of other forms of genetic variation, such as structural variation, mainly in the form of copy number variants (CNVs). Known CNVs account for over 15% of the assembled human genome sequence. Since CNVs are not easily tagged by SNPs, might have a wide range of copy number variability, and often fall in genomic regions not well covered by whole-genome arrays or not genotyped by the HapMap project, current GWASs have largely missed the contribution of CNVs to complex disorders. In fact, some CNVs have already been reported to show association with several complex disorders using candidate gene/region approaches, underpinning the importance of regions not investigated in current GWASs. This reveals the need for new generation arrays (some already in the market) and the use of tailored approaches to explore the full dimension of genome variability beyond the single nucleotide scale

The health impact of nature exposure and green exercise across the life course: a pilot study

Background: Both nature exposure and green exercise (GE) provide numerous health benefits. However, there are no studies examining the impact of childhood GE on adult health. Methods: 45 healthy adults (aged 69.8 ± 8.4 years) took part in the study, wearing a Firstbeat heart rate variability (HRV) monitor for 24 hours. Participants also completed questionnaires assessing childhood and adulthood nature exposure and GE, as well as current connectedness to nature (CN), perceived stress and well-being. Pearson’s correlations and linear regression were used to examine relationships between variables. Results: Childhood nature exposure and GE significantly predicted adult nature exposure and GE (β .317, p < 0.05) as well as CN (β = .831, p < 0.01). After controlling for childhood nature exposure and GE, CN was negatively associated with the percentage of stress over the 24-hour period (r = −.363; p < 0.05) and positively associated with HRV during sleep (r = .415; p < 0.05). Conclusions: CN is important for adult health; however childhood nature exposure and GE are essential to developing this connection