Whom Do Nascent Ventures Search for? Resource Scarcity and Linkage Formation Activities during New Product Development Processes

External linkages allow nascent ventures to access crucial resources during the process of new product development. Forming external linkages can substantially contribute to a venture’s performance. However, little is known about the paths of external linkage formation, as well as the circumstances that drive the choice to pursue one rather than another path. This gap deserves further investigation, because we do not know whether insights developed for incumbent firms also apply to nascent ventures: To address this gap, we explore a novel dataset of 370 venture creation processes. Using sequence analyses based on optimal matching techniques and cluster analyses, we reveal that nascent ventures pursue one of overall four distinct paths of linkage formation activities during new product development. Contrary to the findings of the strategy literature, we find that if nascent ventures engage in external linkages at all, they do not combine exploration- and exploitation-oriented linkages but form either exploration- or exploitation-oriented linkages. Additional regression analyses highlight the circumstances that lead nascent ventures to pursue one rather than the other pathways. Taken together, our analyses point out that resource scarcity constitutes an important factor shaping the linkage formation activities of nascent ventures. Accordingly, we show that nascent ventures tend not to optimize by adding complementary knowledge to the firm’s knowledge base but rather to extend the existing knowledge base—a strategy which we call bricolage.Introduction Linkage formation by nascent ventures in new product development Methods and data Results Discussion and conclusions Notes References Acknowledgement

Harnessing the Power of Information to Protect Our Public Natural Resource Legacy

In practice, our laws have proven unequal to the lofty objectives of preserving a legacy of public natural resources for our children or achieving sustainable use of these resources. There are many factors that contribute to this shortfall, but inherent inadequacies in the design of these statutes cannot be overlooked as an important determinant. Despite the statutes\u27 broadly stated aspirations toward sustainability and protection of the interests of future generations, only a handful of these statutes include strong and enforceable mandates for sustainable resource use. Many of these statutes accord natural resource-management agencies broad discretion to balance and permit a long list of competing uses of a given resource, including degrading and depleting uses. They lack any clear mandate that the agency protect any particular quantity or quality of a given resource for today, much less for future generations. Thus our laws often promise far more than they can deliver. It should therefore come as no surprise that in practice, many of our public natural resources are declining in quantity and quality. Without an effective legal mechanism to check the decline, this pattern of incremental resource depletion and degradation will likely continue. This article considers the possibility that we need, and should consider enacting, a law that provides an effective check on the degradation and depletion of public natural resources across the board. This article considers whether the National Environmental Policy Act (NEPA), reinforced with a substantive standard of protection, would be the best tool for defining and protecting a public natural resource legacy

Harnessing the Power of Information to Protect Our Public Natural Resource Legacy

In practice, our laws have proven unequal to the lofty objectives of preserving a legacy of public natural resources for our children or achieving sustainable use of these resources. There are many factors that contribute to this shortfall, but inherent inadequacies in the design of these statutes cannot be overlooked as an important determinant. Despite the statutes\u27 broadly stated aspirations toward sustainability and protection of the interests of future generations, only a handful of these statutes include strong and enforceable mandates for sustainable resource use. Many of these statutes accord natural resource-management agencies broad discretion to balance and permit a long list of competing uses of a given resource, including degrading and depleting uses. They lack any clear mandate that the agency protect any particular quantity or quality of a given resource for today, much less for future generations. Thus our laws often promise far more than they can deliver. It should therefore come as no surprise that in practice, many of our public natural resources are declining in quantity and quality. Without an effective legal mechanism to check the decline, this pattern of incremental resource depletion and degradation will likely continue. This article considers the possibility that we need, and should consider enacting, a law that provides an effective check on the degradation and depletion of public natural resources across the board. This article considers whether the National Environmental Policy Act (NEPA), reinforced with a substantive standard of protection, would be the best tool for defining and protecting a public natural resource legacy

Determinants of Effective Population Size for Loci with Different Modes of Inheritance

Here we report an assessment of the determinants of effective population size (Ne) in species with overlapping generations. Specifically, we used a stochastic demographic model to investigate the influence of different life-history variables on Ne/N (where N = population census number) and the influence of sex differences in life-history variables on Ne for loci with dif¬ferent modes of inheritance. We applied an individual-based modeling approach to two datasets: one from a natural popu¬lation of savannah baboons (Papio cynocephalus) in the Amboseli basin of southern Kenya and one from a human tribal pop¬ulation (the Gainj of Papua New Guinea). Simulation-based estimates of Ne/N averaged 0.329 for the Amboseli baboon population (SD = 0.116, 95% CI = 0.172 – 0.537) and 0.786 for the Gainj (SD = 0.184, 95% CI = 0.498 – 1.115). Although variance in male fitness had a substantial impact on Ne/N in each of the two primate populations, ratios of Ne values for au¬tosomal and sex-linked loci exhibited no significant departures from Poisson-expected values. In each case, similarities in sex-specific Ne values were attributable to the unexpectedly high variance in female fitness. Variance in male fitness resulted primarily from age-dependent variance in reproductive success, whereas variance in female fitness resulted primarily from stochastic variance in survival during the reproductive phase

Molecular evolution of cytochrome \u3ci\u3eb\u3c/i\u3e in high- and low-altitude deer mice (genus \u3ci\u3ePeromyscus\u3c/i\u3e)

Patterns of amino-acid polymorphism in human mitochondrial genes have been interpreted as evidence for divergent selection among populations that inhabit climatically distinct environments. If similar patterns are mirrored in other broadly distributed mammalian species, then adaptive modifications of mitochondrial protein function may be detected in comparisons among locally adapted populations of a single wide-ranging species, or among closely related species that have adapted to different environments. Here, we test for evidence of positive selection on cytochrome b variation within and among species of the ecologically diverse rodent genus Peromyscus. We used likelihood-based comparisons of synonymous and nonsynonymous substitution rates to test for evidence of divergent selection between high- and low-altitude haplogroups of the deer mouse, Peromyscus maniculatus. We also tested for evidence of divergent selection among different species of Peromyscus that inhabit different thermal environments. In contrast to the purported evidence for positive selection on mitochondrial proteins in humans and other nonhuman mammals, results of our tests suggest that the evolution of cytochrome b in Peromyscus is chiefly governed by purifying selection

Molecular evolution of cytochrome \u3ci\u3eb\u3c/i\u3e in high- and low-altitude deer mice (genus \u3ci\u3ePeromyscus\u3c/i\u3e)

Patterns of amino-acid polymorphism in human mitochondrial genes have been interpreted as evidence for divergent selection among populations that inhabit climatically distinct environments. If similar patterns are mirrored in other broadly distributed mammalian species, then adaptive modifications of mitochondrial protein function may be detected in comparisons among locally adapted populations of a single wide-ranging species, or among closely related species that have adapted to different environments. Here, we test for evidence of positive selection on cytochrome b variation within and among species of the ecologically diverse rodent genus Peromyscus. We used likelihood-based comparisons of synonymous and nonsynonymous substitution rates to test for evidence of divergent selection between high- and low-altitude haplogroups of the deer mouse, Peromyscus maniculatus. We also tested for evidence of divergent selection among different species of Peromyscus that inhabit different thermal environments. In contrast to the purported evidence for positive selection on mitochondrial proteins in humans and other nonhuman mammals, results of our tests suggest that the evolution of cytochrome b in Peromyscus is chiefly governed by purifying selection

Contributions of phenotypic plasticity to differences in thermogenic performance between highland and lowland deer mice

Small mammals face especially severe thermoregulatory challenges at high altitude because the reduced O2 availability constrains the capacity for aerobic thermogenesis. Adaptive enhancement of thermogenic performance under hypoxic conditions may be achieved via physiological adjustments that occur within the lifetime of individuals (phenotypic plasticity) and/or genetically based changes that occur across generations, but their relative contributions to performance differences between highland and lowland natives are unclear. Here, we examined potentially evolved differences in thermogenic performance between populations of deer mice (Peromyscus maniculatus) that are native to different altitudes. The purpose of the study was to assess the contribution of phenotypic plasticity to population differences in thermogenic performance under hypoxia. We used a common-garden deacclimation experiment to demonstrate that highland deer mice have enhanced thermogenic capacities under hypoxia, and that performance differences between highland and lowland mice persist when individuals are born and reared under common-garden conditions, suggesting that differences in thermogenic capacity have a genetic basis. Conversely, population differences in thermogenic endurance appear to be entirely attributable to physiological plasticity during adulthood. These combined results reveal distinct sources of phenotypic plasticity for different aspects of thermogenic performance, and suggest that thermogenic capacity and endurance may have different mechanistic underpinnings. Includes Supplementary material

The simplicity project: easing the burden of using complex and heterogeneous ICT devices and services

As of today, to exploit the variety of different "services", users need to configure each of their devices by using different procedures and need to explicitly select among heterogeneous access technologies and protocols. In addition to that, users are authenticated and charged by different means. The lack of implicit human computer interaction, context-awareness and standardisation places an enormous burden of complexity on the shoulders of the final users. The IST-Simplicity project aims at leveraging such problems by: i) automatically creating and customizing a user communication space; ii) adapting services to user terminal characteristics and to users preferences; iii) orchestrating network capabilities. The aim of this paper is to present the technical framework of the IST-Simplicity project. This paper is a thorough analysis and qualitative evaluation of the different technologies, standards and works presented in the literature related to the Simplicity system to be developed

Bridging the empathy gap: or not? Reactions to ingroup and outgroup facial expressions

Prior research suggests that group membership impacts behavioral and self-reported responses to others’ facial expressions of emotion. In this paper, we examine how the mere labelling of a face as an ingroup or outgroup member affects facial mimicry (Study 1) and judgments of genuineness (Study 2). In addition, we test whether the effects of group membership on facial mimicry and perceived genuineness are moderated by the presence of tears (Study 1) and the motivation to cooperate (Study 2). Results from both studies revealed group-specific biases in facial mimicry and judgments of genuineness. However, introducing cooperative goals abolished differences in judgments of genuineness of facial expressions displayed by ingroup and outgroup members. Together, the findings provide insights into how intergroup biases in emotion perception operate and how they can be reduced by introducing cooperative goals

Gene Turnover and Diversification of the α- and β- Globin Gene Families in Sauropsid Vertebrates

The genes that encode the α- and β-chain subunits of vertebrate hemoglobin have served as a model system for elucidating general principles of gene family evolution, but little is known about patterns of evolution in amniotes other than mammals and birds. Here,we report a comparative genomic analysis of the α- and β-globin gene clusters in sauropsids (archosaurs and nonavian reptiles). The objectives were to characterize changes in the size and membership composition of the α- and β-globin gene families within and among the major sauropsid lineages, to reconstruct the evolutionary history of the sauropsid α- and β-globin genes, to resolve orthologous relationships, and to reconstruct evolutionary changes in the developmental regulation of gene expression. Our comparisons revealed contrasting patterns of evolution in the unlinked α- and β-globin gene clusters. In the α-globin gene cluster,which has remained in the ancestral chromosomal location, evolutionary changes in gene content are attributable to the differential retention of paralogous gene copies that were present in the common ancestor of tetrapods. In the β-globin gene cluster, which was translocated to a new chromosomal location, evolutionary changes in gene content are attributable to differential gene gains (via lineage-specific duplication events) and gene losses (via lineage-specific deletions and inactivations). Consequently, all major groups of amniotes possess unique repertoires of embryonic and postnatally expressed β-type globingenes that diversified independently in each lineage.These independently derived β-type globins descend from a pair of tandemly linked paralogs in the most recent common ancestor of sauropsids