Laboratory observations of slow earthquakes and the spectrum of tectonic fault slip modes

Slow earthquakes represent an important conundrum in earthquake physics. While regular earthquakes are catastrophic events with rupture velocities governed by elastic wave speed, the processes that underlie slow fault slip phenomena, including recent discoveries of tremor, slow-slip and low-frequency earthquakes, are less understood. Theoretical models and sparse laboratory observations have provided insights, but the physics of slow fault rupture remain enigmatic. Here we report on laboratory observations that illuminate the mechanics of slow-slip phenomena. We show that a spectrum of slow-slip behaviours arises near the threshold between stable and unstable failure, and is governed by frictional dynamics via the interplay of fault frictional properties, effective normal stress and the elastic stiffness of the surrounding material. This generalizable frictional mechanism may act in concert with other hypothesized processes that damp dynamic ruptures, and is consistent with the broad range of geologic environments where slow earthquakes are observed

Ganglion cell complex analysis in glaucoma patients: what can it tell us?

Glaucoma is a group of optic neuropathies characterized by a progressive degeneration of retina ganglion cells (RGCs) and their axons that precedes functional changes detected on the visual field. The macular ganglion cell complex (GCC), available in commercial Fourier-domain optical coherence tomography, allows the quantification of the innermost retinal layers that are potentially involved in the glaucomatous damage, including the retinal nerve fiber (RNFL), ganglion cell and inner plexiform layers. The average GCC thickness and its related parameters represent a reliable biomarker in detecting preperimetric glaucomatous damage. The most accurate GCC parameters are represented by average and inferior GCC thicknesses, and they can be associated with progressive visual field loss. Although the diagnostic accuracy increases with more severe glaucomatous damage and higher signal strength values, it is not affected by increasing axial length, resulting in a more accurate discrimination of glaucomatous damage in myopic eyes with respect to the traditional RNFL thickness. The analysis of the structure-function relationship revealed a good agreement between the loss in retinal sensitivity and GCC thickness. The use of a 10-2° visual field grid, adjusted for the anatomical RGCs displacement, describes more accurately the relationship between RGCs thickness and visual field sensitivity loss

A Revised Orbital Ephemeris for HAT-P-9b

We present here three transit observations of HAT-P-9b taken on 14 February 2010, 18 February 2010, and 05 April 2010 UT from the University of Arizona's 1.55 meter Kuiper telescope on Mt. Bigelow. Our transit light curves were obtained in the I filter for all our observations, and underwent the same reduction process. All three of our transits deviated significantly (approximately 24 minutes earlier) from the ephemeris of Shporer et al. (2008). However, due to the large time span between our observed transits and those of Shporer et al. (2008), a 6.5 second (2 sigma) shift downwards in orbital period from the value of Shporer et al. (2008) is sufficient to explain all available transit data. We find a new period of 3.922814 +/- 0.000002 days for HAT-P-9b with no evidence for significant nonlinearities in the transit period.Comment: 10 pages, 3 figure

The role of shear fabric in controlling breakdown processes during laboratory slow-slip events

Understanding the physical mechanisms at the origin of slow-slip events has been proven a very challenging task. In particular, little is known on the role of fault heterogeneity during slow slip. In this study, we provide evidences that fault fabric controls slip velocity time histories during slow-slip events generated in the laboratory. We performed experiments using a double-direct biaxial shear apparatus and two different fault gouges, homogeneous quartz powder, and heterogeneous anhydrite/dolomite mixture. We measure details of fault slip to resolve the slip velocity function and volumetric deformation that, coupled with an analysis of the resulting microstructure, allow us to infer the mechanical processes at play. Our results show that slow-slip events can be generated for both fault gouges when k ~ kc with similar values of breakdown work. The shear fabric exerts a strong influence during the coseismic breakdown stage. In quartz, where most of the slip occurs on a very localized slipping surface, the peak slip velocity is attained near the final stage of friction breakdown and therefore a relevant amount of the mechanical work is absorbed during slip acceleration. In anhydrite/dolomite mixture, the peak slip velocity is suddenly reached after a relatively small drop in friction, accompanied by fault dilation, implying that most of the mechanical work is absorbed during slip deceleration. For anhydrite/dolomite mixture these results are likely related to heterogeneous slip distribution along the observed foliation. Taken together, these observations suggest that the mechanics of slow-slip events depends on shear zone fabric

First optical validation of a Schwarzschild Couder telescope: the ASTRI SST-2M Cherenkov telescope

The Cherenkov Telescope Array (CTA) represents the most advanced facility designed for Cherenkov Astronomy. ASTRI SST-2M has been developed as a demonstrator for the Small Size Telescope in the context of the upcoming CTA. Its main innovation consists in the optical layout which implements the Schwarzschild-Couder configuration and is fully validated for the first time. The ASTRI SST-2M optical system represents the first qualified example for two mirrors telescope for Cherenkov Astronomy. This configuration permits to (i) maintain a high optical quality across a large FoV (ii) de-magnify the plate scale, (iii) exploit new technological solutions for focal plane sensors. The goal of the paper is to present the optical qualification of the ASTRI SST-2M telescope. The qualification has been obtained measuring the PSF sizes generated in the focal plane at various distance from the optical axis. These values have been compared with the performances expected by design. After an introduction on the Gamma Astronomy from the ground, the optical design and how it has been implemented for ASTRI SST-2M is discussed. Moreover the description of the setup used to qualify the telescope over the full field of view is shown. We report the results of the first--light optical qualification. The required specification of a flat PSF of $\sim 10$ arcmin in a large field of view ~10 deg has been demonstrated. These results validate the design specifications, opening a new scenario for Cherenkov Gamma ray Astronomy and, in particular, for the detection of high energy (5 - 300 TeV) gamma rays and wide-field observations with CTA.Comment: 6 pages, 5 figure

An improved method of supercharged transposed latissimus dorsi flap with the skin paddle for the management of a complicated lumbosacral defect

OBJECTIVE: Treatment of nonhealing wounds of lower back often poses a powerful challenge. We present one of the first report of treatment of a lumbosacral defect with a supercharged latissimus dorsi flap with the skin paddle. CASE REPORT: We report a case of a 59 yearold man with myeloma of the sacral spine who underwent radiotherapy and chemotherapy and subsequently, laminectomies and placement of hardware for ongoing paresis and spine instability. Then, he developed an open wound and osteomyelitis of the spine with culture positive tuberculous granulomas. After multiple surgical debridement, he presented to our service and was treated with a single stage debridement followed by the performance of a latissimus dorsi musculocutaneous flap based on paraspinal perforators and supercharged. RESULTS: This solution, allowed for augmentation of blood flow to the muscle with the inferior gluteal artery, provided coverage of the defect resistant to the pressure, and simplified post-operative management of the patient. CONCLUSIONS: Alternative treatment options, including free tissue transfer, posed difficulties in finding suitable recipient vessels near the defect, in inserting the flap so as to restore its original length without compromising blood flow, and in postoperative care of the patient. Treatment of a lumbosacral defect with a supercharged latissimus dorsi flap with the skin paddle may represent a milestone procedure for complicated lower spine wounds

Stabilization of fault slip by fluid injection in the laboratory and in situ

Faults can slip seismically or aseismically depending on their hydromechanical properties, which can be measured in the laboratory. Here, we demonstrate that fault slip induced by fluid injection in a natural fault at the decametric scale is quantitatively consistent with fault slip and frictional properties measured in the laboratory. The increase in fluid pressure first induces accelerating aseismic creep and fault opening. As the fluid pressure increases further, friction becomes mainly rate strengthening, favoring aseismic slip. Our study reveals how coupling between fault slip and fluid flow promotes stable fault creep during fluid injection. Seismicity is most probably triggered indirectly by the fluid injection due to loading of nonpressurized fault patches by aseismic creep

Astrocyte function is affected by aging and not Alzheimer's disease: A preliminary investigation in hippocampi of 3xTg-AD mice

Old age is a risk factor for Alzheimer's disease (AD), which is characterized by hippocampal impairment together with substantial changes in glial cell functions. Are these alterations due to the disease progression or are they a consequence of aging? To start addressing this issue, we studied the expression of specific astrocytic and microglial structural and functional proteins in a validated transgenic model of AD (3×Tg-AD). These mice develop both amyloid plaques and neurofibrillary tangles, and initial signs of the AD-like pathology have been documented as early as three months of age. We compared male 3×Tg-AD mice at 6 and 12 months of age with their wild-type age-matched counterparts. We also investigated neurons by examining the expression of both the microtubule-associated protein 2 (MAP2), a neuronal structural protein, and the brain-derived neurotrophic factor (BDNF). The latter is indeed a crucial indicator for synaptic plasticity and neurogenesis/ neurodegeneration. Our results show that astrocytes are more susceptible to aging than microglia, regardless of mouse genotype. Moreover, we discovered significant agedependent alterations in the expression of proteins responsible for astrocyte-astrocyte and astrocyte-neuron communication, as well as a significant age-dependent decline in BDNF expression. Our data promote further research on the unexplored role of astroglia in both physiological and pathological aging

Isolated, Massive Supergiants near the Galactic Center

We have carried out a pilot project to assess the feasibility of using radio, infrared, and X-ray emission to identify young, massive stars located between 1 and 25 pc from the Galactic center. We first compared catalogs compiled from the Very Large Array, the Chandra X-ray Observatory, and 2MASS. We identified two massive, young stars: the previously-identified star that is associated with the radio HII region H2, and a newly-identified star that we refer to as CXOGC J174516.1-290315. The infrared spectra of both stars exhibit very strong Br-gamma and He I lines, and resemble those of massive supergiants that have evolved off of the main sequence, but not yet reached the Wolf-Rayet phase. We estimate that each star has a bolometric luminosity >10^6 L_sun. The detection of these two sources in X-rays is surprising, because stars at similar evolutionary states are not uniformly bright X-ray sources. Therefore, we suggest that both stars are in binary systems that contain either OB stars whose winds collide with those of the luminous supergiants, or compact objects that are accreting from the winds of the supergiants. We also identify X-ray emission from a nitrogen-type Wolf-Rayet star and place upper limits on the X-ray luminosities of three more evolved, massive stars that previously have been identified between 1 and 25 pc from Sgr A*. Finally, we briefly discuss the implications that future searches for young stars will have for our understanding of the recent history of star formation near the Galactic center. (abridged)Comment: 9 pages, including 8 figures. Submitted to ApJ, and modified in response to referee's repor

Frictional strengthening explored during non-steady state shearing. Implications for fault stability and slip event recurrence time

On natural faults that host repeating slip events, the inter-event loading time is quite large compared to the slip event duration. Since most friction studies focus on steady-state frictional behavior, the fault loading phase is not typically examined. Here, we employ a method specifically designed to evaluate fault strength evolution during active loading, under shear driving rates as low as 10−10 m/s, on natural fault gouge samples from the Waikukupa Thrust in southern New Zealand. These tests reveal that in the early stages of loading following a slip event, there is a period of increased stability, which fades with accumulated slip. In the framework of rate- and state-dependent friction laws, this temporary stable phase exists as long as slip is less than the critical slip distance and the elapsed time is less than the value of the state variable at steady state. These observations indicate a minimum earthquake recurrence time, which depends on the field value of the critical slip distance and the background slip rate. We compare estimates of minimum earthquake recurrence times with the recurrence times of repeating large earthquakes on the Alpine Fault in southern New Zealand and repeating small-magnitude earthquakes on the San Andreas Fault system in California. We find that the observed recurrence times are mostly longer than the predicted minimum values, and exceptions in the San Andreas system may be explained by elevated slip rates due to larger earthquakes in this region