Activities of National Hellenic Documentation Centre and the National Network of Scientific and Technological Libraries

Περιέχει το πλήρες κείμενοThe mission of National (Hellenic) Documentation Centre (NDC)is to ensure the flow of the scientific and technological information to the Hellenic scientific community. This is achieved by establishing online access to 17 international hosts and 1.300 databases, acting as the major information intermediary in the country offering bibliographic references to 10.000 scientst per year, producing 8 national databases and hosting 40 databases produced by other national or international organisations. Concerning libraries NDC supports them by developing and disseminating ABEKT, the most popular library automation software in the country numbering more than 700 copies installed, developing, in close collaboration with 206 libraries, the Union Catalogue of Periodicals including 22.790 unique journal titles, creating and coordinating the National Network of Hellenic Scientific Libraries with 107 libraries supporting interlibrary loan through the online document ordering system provided by the host computer of NDC, developing its own digital library having access to more than 230 electronic journals via internet and about 1.000 installed locally, organising seminars, workshops and information days focusing on the electronic information services and technologies

Effects of countdown displays in public transport route choice under severe overcrowding

The paper presents a route choice model for dynamic assignment in congested, i.e. overcrowded, transit networks where it is assumed that passengers are supported with real-time information on carrier arrivals at stops. If the stop layout is such that passenger congestion results in First-In-First-Out (FIFO) queues, a new formulation is devised for calculating waiting times, total travel times and route splits. Numerical results for a simple example network show the effect of information on route choice when heavy congestion is observed. While the provision of information does not lead to a remarkable decrease in total travel time, with the exception of some particular instances, it changes the travel behaviour of passengers that seem to be more averse to queuing at later stages of their journey and, thus, prefer to interchange at less congested stations

N-3 PUFA Supplementation Triggers PPAR-α Activation and PPAR-α/NF-κB Interaction: Anti-Inflammatory Implications in Liver Ischemia-Reperfusion Injury

Dietary supplementation with the n-3 polyunsaturated fatty acids (n-3 PUFA) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) to rats preconditions the liver against ischemia-reperfusion (IR) injury, with reduction of the enhanced nuclear factor-κB (NF-κB) functionality occurring in the early phase of IR injury, and recovery of IR-induced pro-inflammatory cytokine response. The aim of the present study was to test the hypothesis that liver preconditioning by n-3 PUFA is exerted through peroxisone proliferator-activated receptor α (PPAR-α) activation and interference with NF-κB activation. For this purpose we evaluated the formation of PPAR-α/NF-κBp65 complexes in relation to changes in PPAR-α activation, IκB-α phosphorylation and serum levels and expression of interleukin (IL)-1β and tumor necrosis factor (TNF)-α in a model of hepatic IR-injury (1 h of ischemia and 20 h of reperfusion) or sham laparotomy (controls) in male Sprague Dawley rats. Animals were previously supplemented for 7 days with encapsulated fish oil (General Nutrition Corp., Pittsburg, PA) or isovolumetric amounts of saline (controls). Normalization of IR-altered parameters of liver injury (serum transaminases and liver morphology) was achieved by dietary n-3 PUFA supplementation. EPA and DHA suppression of the early IR-induced NF-κB activation was paralleled by generation of PPAR-α/NF-κBp65 complexes, in concomitance with normalization of the IR-induced IκB-α phosphorylation. PPAR-α activation by n-3 PUFA was evidenced by enhancement in the expression of the PPAR-α-regulated Acyl-CoA oxidase (Acox) and Carnitine-Palmitoyl-CoA transferase I (CPT-I) genes. Consistent with these findings, normalization of IR-induced expression and serum levels of NF-κB-controlled cytokines IL-lβ and TNF-α was observed at 20 h of reperfusion. Taken together, these findings point to an antagonistic effect of PPAR-α on NF-κB-controlled transcription of pro-inflammatory mediators. This effect is associated with the formation of PPAR-α/NF-κBp65 complexes and enhanced cytosolic IκB-α stability, as major preconditioning mechanisms induced by n-3 PUFA supplementation against IR liver injury

Employment status and commute distance of Canadians with disabilities

Disabilities, Impairments, Employment status, Commute distance, 2006 Participation and Activity Limitation Survey, Canada,

Car ownership motivations among undergraduate students in China, Indonesia, Japan, Lebanon, Netherlands, Taiwan, and USA

‘‘Peak car’’ and related discussions suggest that especially younger people (age cohort until 30) have less desire to drive and purchase cars. This might though only be true for a limited range of developed countries. This study aims to understand the role of personal background and the country context influencing future car ownership decisions of younger people in seven countries (China, Indonesia, Japan, Lebanon, Netherlands, Taiwan, and USA). The main foci of this research are undergraduate students where it is expected that their current attitudes and habits will influence their travel behavior after they graduate and obtain a job. A web survey asked students about their attitudes towards car and public transportation, social norms, their socio-demographic situations, current mobility patterns and the intention to own a car after graduation. We conducted a descriptive analysis as well as correlation analysis of the survey data focusing on explaining intentions to own a car in the future. We find that there is a significant difference between developing and developed countries; students in developed countries have less desire to purchase cars. Expectations of others appears an important determinant of purchase intentions whereas income and the symbolic affective meaning of the car are less correlated with intentions