117 research outputs found

    An Examination of Relevant Issues in Nigeria’s Fiscal Federalism

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    Nigeria’s fiscal arrangement accommodates the interaction between the federal government and the federating units in addressing critical issues of revenue assignment from natural resources, expenditure assignment, regional disparities, and national unity. Fiscal federalism in Nigeria is characterized by extensive vertical and horizontal intergovernmental relations which have become very contentious and volatile because subnational governments lack financial autonomy in the current fiscal architecture. This paper examines such issues as principles of fiscal federalism, decentralization and assignment of revenue from natural resources, decentralization and corruption, decentralization, regional disparities and national unity. The practice of fiscal federalism has been contentious in Nigeria due to overbearing influence of the federal government, unevenly distribution of endowment of natural resources, the sharing of which often puts considerable strains on national unity, and also tends to generate rivalries between the constituent units of the Nigerian state. The paper concludes that if the country can establish the institutions that will make decentralization work with a reasonable degree of efficiency, then decentralization can be a good policy

    Nutritional status and morbidity in children 0-5years seen in Jos University Teaching Hospital

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    Malnutrition underlies more than 50% of childhood mortality in Nigeria. It contributes significantly to mortality rates in children less than 5years of age. Prevalent childhood illnesses beyond the neonatal period are acute respiratory infections amongst other and outcome of treatment is invariably related to nutritional status. We sought to  determine the morbidity pattern and nutritional status of children 5 years and below admitted into the children emergency unit without primary diagnosis of malnutrition. Consenting subjects over a one year period between  0-5years were recruited into the study. Data retrieved included age, sex, weight, length/height and mid-upper arm circumference, clinical diagnosis amongst others. Seventy three subjects 5years and below were recruited out of 113 patients seen during the period. Mean age 21.518.5months. Most (43.8%) were infants. Acute respiratory infections (pneumonia, bronchiolitis and pharyngotonsillitis) accounted for 51.4% of admission, malaria 22.3% sickle cell  anaemia 8.3% and UTI 6.1% amongst others. Malnutrition was seen in 48.9% using WHZ, 15.1% had severe acute malnutrition, 10.9% were overweight while 9.6% had severe stunting. Most cases of SAM were seen in patients with pneumonia (35.7%). Malaria had mainly subjects with MAM (60%). Over-nutrition was seen more in subjects with UTI (50%), pneumonia (28.4%), bronchiolitis (33.3%) and malaria (20%). Severe stunted was noted among  subjects with pneumonia (21.4%), UTI (25%) and bronchiolitis (33.3%). Malnutrition remains an underlying  co-morbidity in children 5years and below. Intensified efforts at community and clinical management of  malnutrition in all children is needed

    Erosion-corrosion behaviour of dual phase medium carbon steel using a designed slurry pot

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    Abstract: A slurry pot has been designed, fabricated and evaluated for erosion-corrosion investigations. A variable voltage controller was used to vary the input voltage into the one-horse-power motor that controls the slurry pot. The actual speed of the slurry pot shaft was also calibrated using a non-contact digital tachometer. Voltages of 100 and 200 V resulted in rotational speeds of 1100 and 2100 rpm, respectively employed for the subsequent erosion-corrosion tests. Erosion-corrosion of a dual-phase carbon steel was investigated with the aid of the slurry pot in aerated 3.5 wt.% NaCl environments. The sample was normalised at 850 oC and then cooled in air to room temperature. Prior to the test, the normalised samples were heated to 700, 725, 750, 775, 800 and 825 oC, respectively and quenched in oil. Erosion-corrosion rates of between 0.027 to 1.26 g/cm2.hr at 1100 rpm and 0.57 to 1.9 g/cm2.hr at 2100 rpm were recorded. It was also observed that as hardness increased there was reduction in weight loss of the heat treated alloy

    Fiscal Decentralization and Economic Growth in Nigeria: A Multivariate Co-Integration Approach

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    This paper examines the long run and causal relationship between fiscal decentralization and economic growth in Nigeria for the period 1970 to 2012 using time series data. Results from a multivariate VAR model provide evidence of long run relationship between fiscal decentralization and economic growth in Nigeria. The three measures of fiscal decentralization have a positive and significant relationship with economic growth, Granger Causality test reveals long run unidirectional link running from fiscal decentralization to economic growth. The study recommends the need for government to urgently address the constitutional issue of fiscal powers among the three tiers of government to further strengthen the fiscal base of the state and local governments and increase further the level of fiscal decentralization

    Comparing neonatal outcomes in women with preeclampsia and those with normal pregnancy

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    Background: Preeclampsia has remained an important public health problem in the developing world where it is associated with a five-fold increase in perinatal morbidity and mortality. Objective: We set out to compare neonatal outcomes between women with preeclampsia and those with normal pregnancy. We also sought to evaluate factors associated with poor outcome in the neonates. Materials and Methods: This was a prospective cohort study that enrolled 90 women (45 with preeclampsia and 45 with normal pregnancy) after 20 weeks gestation. Maternal socio-demographic and clinical information was obtained at enrolment and delivery using questionnaire. Neonatalanthropometric and physiologic data was obtained at delivery and used for classifying the birth weight according to the WHO classification. APGAR score was used to evaluate the presence of birth asphyxia. We defined poor outcome as the presence of at least one of low birth weight,  prematurity, birth asphyxia and need for admission. SPSS version 25 was used in all analysis. Significance testing was set at p=0.05. Results: The women with preeclampsia were significantly heavier at booking (BMI 29.0±6.9 Kg/ m2 vs 25.0±5.2. p=0.005), have higher mean booking systolic blood pressure (122.±22.6 mmHg vs 111.5±12.7mmHg, p=0.003) and diastolic blood pressure ( 7 9 . 8 ± 1 4 . 3mm Hgvs 68.8±9.0mmHg, p<0.001). Neonates of women with preeclampsia were significantly more premature ( meangestational age = 36 . 8 ± 3 . 2 week svs 38.7±2.0weeks, p=0.001) and lighter (mean birth weight =2,529±817.5g vs 3,079.2±527.4g, p<0.001). Overall, 22 (49.4%) of the neonates of women with preeclampsiahad significantly poor outcome compared with 12(27.4%) of the neonates of women with normal pregnancy (p=0.01). Univariate logistic analysis showed only being a male neonate, maternal preeclampsia and admission in index pregnancy were significantly associated with poor outcome.  Multivariable logistic regression showed only being a male neonate to be 3 times more likely to have a poor outcome (Wald=5.34. OR=3.2, p=0.02) Conclusions: Intrauterine exposure to preeclampsia is associated with poor neonatal outcomes especially in males Key words: infant outcome, preeclampsia, Nigeri

    Validation of KASP-SNP markers in cassava germplasm for marker-assisted selection of increased carotenoid content and dry matter content

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    Open Access Journal; Published online: 12 Oct 2022Provitamin A biofortification and increased dry matter content are important breeding targets in cassava improvement programs worldwide. Biofortified varieties contribute to the alleviation of provitamin A deficiency, a leading cause of preventable blindness common among pre-school children and pregnant women in developing countries particularly Africa. Dry matter content is a major component of dry yield and thus underlies overall variety performance and acceptability by growers, processors, and consumers. Single nucleotide polymorphism (SNP) markers linked to these traits have recently been discovered through several genome-wide association studies but have not been deployed for routine marker-assisted selection (MAS). This is due to the lack of useful information on markers’ performances in diverse genetic backgrounds. To overcome this bottleneck, technical and biological validation of the loci associated with increased carotenoid content and dry matter content were carried out using populations independent of the marker discovery population. In the present study, seven previously identified markers for these traits were converted to a robust set of uniplex allele-specific polymerase chain reaction (PCR) assays and validated in two independent pre-breeding and breeding populations. These assays were efficient in discriminating marker genotypic classes and had an average call rate greater than 98%. A high correlation was observed between the predicted and observed carotenoid content as inferred by root yellowness intensity in the breeding (r = 0.92) and pre-breeding (r = 0.95) populations. On the other hand, dry matter content-markers had moderately low predictive accuracy in both populations (r< 0.40) due to the more quantitative nature of the trait. This work confirmed the markers’ effectiveness in multiple backgrounds, therefore, further strengthening their value in cassava biofortification to ensure nutritional security as well as dry matter content productivity. Our study provides a framework to guide future marker validation, thus leading to the more routine use of markers in MAS in cassava improvement programs

    Clinical Outcomes in 3343 Children and Adults with Rheumatic Heart Disease from 14 Low and Middle Income Countries: 2-Year Follow-up of the Global Rheumatic Heart Disease Registry (the REMEDY study)

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    Background: There are few contemporary data on the mortality and morbidity associated with rheumatic heart disease or information on their predictors. We report the 2-year follow-up of individuals with rheumatic heart disease from 14 low- and middle-income countries in Africa and Asia. Methods: Between January 2010 and November 2012, we enrolled 3343 patients from 25 centers in 14 countries and followed them for 2 years to assess mortality, congestive heart failure, stroke or transient ischemic attack, recurrent acute rheumatic fever, and infective endocarditis. Results: Vital status at 24 months was known for 2960 (88.5%) patients. Two-thirds were female. Although patients were young (median age, 28 years; interquartile range, 18–40), the 2-year case fatality rate was high (500 deaths, 16.9%). Mortality rate was 116.3/1000 patient-years in the first year and 65.4/1000 patient-years in the second year. Median age at death was 28.7 years. Independent predictors of death were severe valve disease (hazard ratio [HR], 2.36; 95% confidence interval [CI], 1.80–3.11), congestive heart failure (HR, 2.16; 95% CI, 1.70–2.72), New York Heart Association functional class III/IV (HR, 1.67; 95% CI, 1.32–2.10), atrial fibrillation (HR, 1.40; 95% CI, 1.10–1.78), and older age (HR, 1.02; 95% CI, 1.01–1.02 per year increase) at enrollment. Postprimary education (HR, 0.67; 95% CI, 0.54–0.85) and female sex (HR, 0.65; 95% CI, 0.52–0.80) were associated with lower risk of death. Two hundred and four (6.9%) patients had new congestive heart failure (incidence, 38.42/1000 patient-years), 46 (1.6%) had a stroke or transient ischemic attack (8.45/1000 patient-years), 19 (0.6%) had recurrent acute rheumatic fever (3.49/1000 patient-years), and 20 (0.7%) had infective endocarditis (3.65/1000 patient-years). Previous stroke and older age were independent predictors of stroke/transient ischemic attack or systemic embolism. Patients from low- and lower-middle–income countries had significantly higher age- and sex-adjusted mortality than patients from upper-middle–income countries. Valve surgery was significantly more common in upper-middle–income than in lower-middle– or low-income countries. Conclusions: Patients with clinical rheumatic heart disease have high mortality and morbidity despite being young; those from low- and lower-middle–income countries had a poorer prognosis associated with advanced disease and low education. Programs focused on early detection and the treatment of clinical rheumatic heart disease are required to improve outcomes. </jats:sec

    Mind the gaps! A research agenda for urban interstices

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    Processes of urbanisation can hardly be considered without reference to the spaces that lie between developments. However, the literature on such interstitial spaces is fragmentary. In this paper we draw together insights from the extant literature into a research agenda on urban interstices. We propose a research agenda centred on four themes: the multiple geographic scales at which the interstitial spaces of urban sprawl might be analysed; the pending nature of such spaces; their planned or unplanned character and their relational properties. We develop these themes, briefly illustrating them with reference to the case of metropolitan area of Santiago de Chile. In conclusion, we emphasise some of the implications of interstitial spaces for theories of urban politics and their value in forcing inter-disciplinarity in urban studies

    The application of ‘elite interviewing’ methodology in transdisciplinary research: A record of process and lessons learned during a 3-year pilot in urban planetary health research

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    This paper sets out the rationale and process for the interviewing methodology utilized during a 3-year research pilot, ‘Moving Health Upstream in Urban Development’ (UPSTREAM). The project had two primary aims: firstly, to attempt to value economically the health cost benefits associated with the quality of urban environments and secondly, to engage with those in control of urban development in the UK in order to determine what are the barriers to and opportunities for creating healthy urban environments, including those identified through the utilisation of economic valuation. Engagement at senior level with those who have most control over key facets of planning and development implementation—such as land disposal, investment, development delivery and planning permission—was central to the approach, which encompassed the adoption of ‘elite interviewing’, a method developed in the USA in the 1950s and used in the political sciences but relatively unutilized in the health and environmental sciences [1]. Two rounds of semi-structured interviews were undertaken with 15 senior decision-makers from the UK’s main urban development delivery agencies, both public and private. The ‘elite interviewing’ approach successfully enabled the UPSTREAM project to capture and analyse the information received from the interviewees, all of whom held influential or leadership posts in organisations that are important actors in the process of planning, developing and constructing the built environment in the UK. Having academic and practitioner research leads on an equal footing created some minor tensions, but it also appeared to strengthen the rigor of the approach through a broad knowledge of context ‘in-house’. This form of co-production at times challenged academic traditions in qualitative analysis, but it also appeared to build trust with interviewees and provided greater clarity of the real-world context under investigation. Findings from this study are written up in a separate paper

    Prevalence and Predictors of Tuberculosis Coinfection among HIV-Seropositive Patients Attending the Aminu Kano Teaching Hospital, Northern Nigeria

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    Background: The HIV/AIDS epidemic has been accompanied by a severe epidemic of tuberculosis (TB), although the prevalence of coinfection is largely unknown, especially in developing countries, including Nigeria. The aim of this study was to determine the prevalence and predictors of TB coinfection among HIV-seropositive Nigerians. Methods: The case files of HIV/AIDS patients attending Aminu Kano Teaching Hospital, Nigeria from January to December 2006 were reviewed. Results: A total of 1320 HIV/AIDS patients had complete records and were reviewed, among which 138 (10.5%) were coinfected with TB (95% CI, 8.9% to 12.2%). Pulmonary TB was diagnosed in 103 (74.6%) patients, among whom only 18 (17.5%) were sputum-positive. Fifty (36.2%) coinfected patients had some type of extrapulmonary TB (EPTB); 15 had both pulmonary TB and EPTB. Among the 35 patients with EPTB only, 20 (57.1%) had abdominal TB, 5 (14.3%) had TB adenitis, 5 (14.3%) had spinal TB, 3 (8.6%) were being monitored for tuberculous meningitis, and 1 (2.9%) each had renal TB and tuberculous adrenalitis. The highest prevalence of TB, 13.7% (n = 28), was seen among patients aged 41–50 years. TB coinfection was significantly associated with marital status, WHO clinical stage, and CD4 count. Marital status (OR, 2.1; 95% CI, 1.28–3.59; P = 0.04), WHO clinical stage at presentation (4.81; 1.42–8.34; P = 0.001), and baseline CD4 count (2.71; 1.51–6.21; P = 0.02) remained significant predictors after adjustment for confounding. Conclusions: The moderately high prevalence of TB among HIV-seropositive patients underscores the urgent need for strategies that lead to rapid identification and treatment of coinfection with active or latent TB
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