New hospital disinfection processes for both conventional and prion infectious agents compatible with thermosensitive medical equipment.

International audienc

Serotonin decreases HIV-1 replication in primary cultures of human macrophages through 5-HT1A receptors

Background and purpose: 5-HT (serotonin) is known to be involved in neuroinflammation and immunoregulation. The human immunodeficiency virus (HIV) targets cells such as monocytes/macrophages, which colocalize with 5-HT-releasing cell types, mostly platelets. In this study, we investigated the effects of 5-HT on HIV-1-infected macrophages in vitro