98 research outputs found
Complex Total Ankle Arthroplasty.
Total ankle arthroplasty is a viable surgical technique for the treatment of end-stage degenerative joint disease. With continued advancement in prosthetic design, refined surgical techniques, and improved outcomes, the indications for total ankle replacement have expanded to include cases of increasing complexity. With meticulous preoperative planning and exacting execution, many frontal plane deformities and cases of avascular necrosis can now be successfully addressed at the time of prosthesis implantation or in a staged procedure
The Use of Decellularized Human Placenta in Full-Thickness Wound Repair and Periarticular Soft Tissue Reconstruction: An Update on Regenerative Healing.
Prolonged or incomplete healing of the foot and ankle can pose significant challenges. Therefore, investigators have begun searching for alternative treatment strategies. With advances in tissue engineering, decellularized human placental connective tissue matrix has been suggested as a means to achieve more rapid and complete healing for various soft tissue and bone procedures. Basic science and clinical studies have shown that decellularized human placental connective tissue matrix can support regenerative healing through cellular migration, accelerated tissue remodeling, and the establishment of functional tissue. Additional research is needed to fully explore and evaluate clinical applications within the foot and ankle
Radioligand binding analysis of receptor subtypes in two FP receptor preparations that exhibit different functional rank orders of potency in response to prostaglandins
ABSTRACT The rat colon and Swiss 3T3 cells have been proposed as FP receptor preparations
Design and Simulated Performance of Calorimetry Systems for the ECCE Detector at the Electron Ion Collider
We describe the design and performance the calorimeter systems used in the
ECCE detector design to achieve the overall performance specifications
cost-effectively with careful consideration of appropriate technical and
schedule risks. The calorimeter systems consist of three electromagnetic
calorimeters, covering the combined pseudorapdity range from -3.7 to 3.8 and
two hadronic calorimeters. Key calorimeter performances which include energy
and position resolutions, reconstruction efficiency, and particle
identification will be presented.Comment: 19 pages, 22 figures, 5 table
ECCE Sensitivity Studies for Single Hadron Transverse Single Spin Asymmetry Measurements
We performed feasibility studies for various single transverse spin
measurements that are related to the Sivers effect, transversity and the tensor
charge, and the Collins fragmentation function. The processes studied include
semi-inclusive deep inelastic scattering (SIDIS) where single hadrons (pions
and kaons) were detected in addition to the scattered DIS lepton. The data were
obtained in {\sc pythia}6 and {\sc geant}4 simulated e+p collisions at 18 GeV
on 275 GeV, 18 on 100, 10 on 100, and 5 on 41 that use the ECCE detector
configuration. Typical DIS kinematics were selected, most notably
GeV, and cover the range from to . The single spin
asymmetries were extracted as a function of and , as well as the
semi-inclusive variables , and . They are obtained in azimuthal moments
in combinations of the azimuthal angles of the hadron transverse momentum and
transverse spin of the nucleon relative to the lepton scattering plane. The
initially unpolarized MonteCarlo was re-weighted in the true kinematic
variables, hadron types and parton flavors based on global fits of fixed target
SIDIS experiments and annihilation data. The expected statistical
precision of such measurements is extrapolated to 10 fb and potential
systematic uncertainties are approximated given the deviations between true and
reconstructed yields. The impact on the knowledge of the Sivers functions,
transversity and tensor charges, and the Collins function has then been
evaluated in the same phenomenological extractions as in the Yellow Report. The
impact is found to be comparable to that obtained with the parameterized Yellow
Report detector and shows that the ECCE detector configuration can fulfill the
physics goals on these quantities.Comment: 22 pages, 22 figures, to be submitted to joint ECCE proposal NIM-A
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ECCE unpolarized TMD measurements
We performed feasibility studies for various measurements that are related to
unpolarized TMD distribution and fragmentation functions. The processes studied
include semi-inclusive Deep inelastic scattering (SIDIS) where single hadrons
(pions and kaons) were detected in addition to the scattered DIS lepton. The
single hadron cross sections and multiplicities were extracted as a function of
the DIS variables and , as well as the semi-inclusive variables ,
which corresponds to the momentum fraction the detected hadron carries relative
to the struck parton and , which corresponds to the transverse momentum of
the detected hadron relative to the virtual photon. The expected statistical
precision of such measurements is extrapolated to accumulated luminosities of
10 fb and potential systematic uncertainties are approximated given the
deviations between true and reconstructed yields.Comment: 12 pages, 9 figures, to be submitted in joint ECCE proposal NIM-A
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Open Heavy Flavor Studies for the ECCE Detector at the Electron Ion Collider
The ECCE detector has been recommended as the selected reference detector for
the future Electron-Ion Collider (EIC). A series of simulation studies have
been carried out to validate the physics feasibility of the ECCE detector. In
this paper, detailed studies of heavy flavor hadron and jet reconstruction and
physics projections with the ECCE detector performance and different magnet
options will be presented. The ECCE detector has enabled precise EIC heavy
flavor hadron and jet measurements with a broad kinematic coverage. These
proposed heavy flavor measurements will help systematically study the
hadronization process in vacuum and nuclear medium especially in the
underexplored kinematic region.Comment: Open heavy flavor studies with the EIC reference detector design by
the ECCE consortium. 11 pages, 11 figures, to be submitted to the Nuclear
Instruments and Methods
AI-assisted Optimization of the ECCE Tracking System at the Electron Ion Collider
The Electron-Ion Collider (EIC) is a cutting-edge accelerator facility that
will study the nature of the "glue" that binds the building blocks of the
visible matter in the universe. The proposed experiment will be realized at
Brookhaven National Laboratory in approximately 10 years from now, with
detector design and R&D currently ongoing. Notably, EIC is one of the first
large-scale facilities to leverage Artificial Intelligence (AI) already
starting from the design and R&D phases. The EIC Comprehensive Chromodynamics
Experiment (ECCE) is a consortium that proposed a detector design based on a
1.5T solenoid. The EIC detector proposal review concluded that the ECCE design
will serve as the reference design for an EIC detector. Herein we describe a
comprehensive optimization of the ECCE tracker using AI. The work required a
complex parametrization of the simulated detector system. Our approach dealt
with an optimization problem in a multidimensional design space driven by
multiple objectives that encode the detector performance, while satisfying
several mechanical constraints. We describe our strategy and show results
obtained for the ECCE tracking system. The AI-assisted design is agnostic to
the simulation framework and can be extended to other sub-detectors or to a
system of sub-detectors to further optimize the performance of the EIC
detector.Comment: 16 pages, 18 figures, 2 appendices, 3 table
Observation of the electromagnetic field effect via charge-dependent directed flow in heavy-ion collisions at the Relativistic Heavy Ion Collider
The deconfined quark-gluon plasma (QGP) created in relativistic heavy-ion
collisions enables the exploration of the fundamental properties of matter
under extreme conditions. Non-central collisions can produce strong magnetic
fields on the order of Gauss, which offers a probe into the
electrical conductivity of the QGP. In particular, quarks and anti-quarks carry
opposite charges and receive contrary electromagnetic forces that alter their
momenta. This phenomenon can be manifested in the collective motion of
final-state particles, specifically in the rapidity-odd directed flow, denoted
as . Here we present the charge-dependent measurements of
near midrapidities for , , and
in Au+Au and isobar (Ru+Ru and
Zr+Zr) collisions at 200 GeV, and
in Au+Au collisions at 27 GeV, recorded by the STAR detector at the
Relativistic Heavy Ion Collider. The combined dependence of the signal on
collision system, particle species, and collision centrality can be
qualitatively and semi-quantitatively understood as several effects on
constituent quarks. While the results in central events can be explained by the
and quarks transported from initial-state nuclei, those in peripheral
events reveal the impacts of the electromagnetic field on the QGP. Our data put
valuable constraints on the electrical conductivity of the QGP in theoretical
calculations
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