101 research outputs found
The incidence of mid-infrared excesses in G and K giants
Using photometric data from the 2MASS and GLIMPSE catalogues, I investigate
the incidence of mid-infrared excesses (~10 microns) of G and K stars of
luminosity class III. In order to obtain a large sample size, stars are
selected using a near-IR colour-magnitude diagram. Sources which are candidates
for showing mid-IR excess are carefully examined and modelled to determined
whether they are likely to be G/K giants. It is found that mid-IR excesses are
present at a level of (1.8 +/- 0.4) x 10^-3. While the origin of these excesses
remains uncertain, it is plausible that they arise from debris discs around
these stars. I note that the measured incidence is consistent with a scenario
in which dust lifetimes in debris discs are determined by Poynting-Robertson
drag rather than by collisions.Comment: Accepted for publication in MNRAS. 13 pages, 5 figures, 2 tables (1
landscape table
From MFN to SFN: Performance Prediction Through Machine Learning
In the last decade, the transition of digital terrestrial television (DTT) systems from multi-frequency networks (MFNs) to single-frequency networks (SFNs) has become a reality. SFN offers multiple advantages concerning MFN, such as more efficient management of the radioelectric spectrum, homogenizing the network parameters, and a potential SFN gain. However, the transition process can be cumbersome for operators due to the multiple measurement campaigns and required finetuning of the final SFN system to ensure the desired quality of service. To avoid time-consuming field measurements and reduce the costs associated with the SFN implementation, this paper aims to predict the performance of an SFN system from the legacy MFN and position data through machine learning (ML) algorithms. It is proposed a ML concatenated structure based on classification and regression to predict SFN electric-field strength, modulation error ratio, and gain. The model's training and test process are performed with a dataset from an SFN/MFN trial in Ghent, Belgium. Multiple algorithms have been tuned and compared to extract the data patterns and select the most accurate algorithms. The best performance to predict the SFN electric-field strength is obtained with a coefficient of determination (R2) of 0.93, modulation error ratio of 0.98, and SFN gain of 0.89 starting from MFN parameters and position data. The proposed method allows classifying the data points according to positive or negative SFN gain with an accuracy of 0.97
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Everolimus Exposure as a Predictor of Toxicity in Renal Cell Cancer Patients in the Adjuvant Setting: Results of a Pharmacokinetic Analysis for SWOG S0931 (EVEREST), a Phase III Study (NCT01120249).
BackgroundS0931 is assessing recurrence-free survival in renal cell carcinoma (RCC) patients randomized to receive everolimus (EVE) versus placebo for one year following nephrectomy. Due to a higher than expected dropout rate, we assessed EVE trough levels in the adjuvant setting to evaluate the relationship between EVE exposure and probability of toxicity.MethodsPatients received 10 mg daily EVE for nine 6-week cycles. Pre-dose whole blood samples were collected pre-cycle 2 and pre-cycle 3 and analyzed for EVE. Patients with pre-cycle 2 and/or pre-cycle 3 EVE results were used in the analysis. Patients were segregated into quartiles (Q) based on EVE levels and logistic regression was used to model the most common adverse event outcomes using EVE trough as a predictor. Hazard and odds ratios were adjusted for age, BMI and performance status.ResultsA total of 467 patients were included in this analysis. Quartiles normalized to an EVE dose of 10 mg/day wereâ<â9.0, 9.0-12.9, 12.9-22.8, andâ>â22.8 ng/mL, respectively. EVE trough levels increased with increasing age (pâ<â0.001). Furthermore, EVE trough levels were higher in men than women (19.4 versus 15.4 ng/mL, pâ=â0.01). Risk of grade 2â+âtriglycerides was increased in Q2 and Q3 vs Q1 (ORâ=â2.08; pâ=â0.02 and ORâ=â2.63; pâ=â0.002). Risk of grade 2â+ârash was increased in Q2 and Q4 vs Q1 (ORâ=â2.99; pâ=â0.01 and ORâ=â2.90; pâ=â0.02). There was also an increased risk of any grade 3â+âtox in Q2 vs Q1 (ORâ=â1.71; pâ=â0.05).ConclusionsWe identified significant gender and age-related differences in EVE trough levels in patients receiving adjuvant treatment for RCC. Furthermore, our analysis identified significant associations between EVE exposure and probability of toxicity
Discovery of Reflection Nebulosity Around Five Vega-like Stars
Coronagraphic optical observations of six Vega-like stars reveal reflection
nebulosities, five of which were previously unknown. The nebulosities
illuminated by HD 4881, HD 23362, HD 23680, HD 26676, and HD 49662 resemble
that of the Pleiades, indicating an interstellar origin for dust grains. The
reflection nebulosity around HD 123160 has a double-arm morphology, but no
disk-like feature is seen as close as 2.5 arcsec from the star in K-band
adaptive optics data. We demonstrate that uniform density dust clouds
surrounding HD 23362, HD 23680 and HD 123160 can account for the observed
12-100 micron spectral energy distributions. For HD 4881, HD 26676, and HD
49662 an additional emission source, such as from a circumstellar disk or
non-equilibrium grain heating, is required to fit the 12-25 micron data. These
results indicate that in some cases, particularly for Vega-like stars located
beyond the Local Bubble (>100 pc), the dust responsible for excess thermal
emission may originate from the interstellar medium rather than from a
planetary debris system.Comment: The Astrophysical Journal, in press for March, 2002 (32 pages, 13
figures
Spitzer 24 micron Survey of Debris Disks in the Pleiades
We performed a 24 micron 2 Deg X 1 Deg survey of the Pleiades cluster, using
the MIPS instrument on Spitzer. Fifty four members ranging in spectral type
from B8 to K6 show 24 micron fluxes consistent with bare photospheres. All Be
stars show excesses attributed to free-free emission in their gaseous
envelopes. Five early-type stars and four solar-type stars show excesses
indicative of debris disks. We find a debris disk fraction of 25 % for B-A
members and 10 % for F-K3 ones. These fractions appear intermediate between
those for younger clusters and for the older field stars. They indicate a decay
with age of the frequency of the dust-production events inside the planetary
zone, with similar time scales for solar-mass stars as have been found
previously for A-stars.Comment: accepted to Ap
Envelope Ejection: an Alternative Process for some Early Case B Binaries
We discuss the evolution of binaries with moderately high masses (about 10 -
30 solar masses), and with periods of about 3 - 300d, corresponding mostly to
early Case B. These are usually thought to evolve either by reasonably
conservative Roche-lobe overflow, if the initial mass ratio is fairly mild, or
else by highly non-conservative common-envelope evolution, with spiral-in to
short periods (hours, typically), if the initial mass ratio is rather extreme.
We discuss here a handful of binaries from part of this period range (about 50
- 250d), which appear to have followed a different path: we argue that they
must have lost a large proportion of initial mass (about 70 - 80%), but without
shortening their periods at all. We suggest that their behaviour may be due to
the fact that stars of such masses, when evolved also to rather large radii,
are not far from the Humphreys-Davidson limit where single stars lose their
envelopes spontaneously in P Cygni winds, and so have envelopes which are only
lightly bound to the core. These envelopes therefore may be relatively easily
dissipated by the perturbing effect of a companion. In addition, some or all of
the stars considered here may have been close to the Cepheid instability strip
when they filled their Roche lobes. One or other, or both, of high luminosity
and Cepheid instability, in combination with an appropriately close binary
companion, may be implicated
A Flared, Orbiting, Dusty Disk Around HD 233517
We find that the infrared excess around HD 233517, a first ascent red giant,
can be naturally explained if the star possesses an orbiting, flared dusty
disk. We estimate that the outer radius of this disk is 45 AU and that the
total mass within the disk is about 0.01 the mass of the Sun. We speculate that
this disk is the result of the engulfment of a low mass companion star that
occurred when HD 233517 became a red giant.Comment: ApJ, in pres
Incidence and survival of remnant disks around main-sequence stars
We present photometric ISO 60 and 170um measurements, complemented by some
IRAS data at 60um, of a sample of 84 nearby main-sequence stars of spectral
class A, F, G and K in order to determine the incidence of dust disks around
such main-sequence stars. Of the stars younger than 400 Myr one in two has a
disk; for the older stars this is true for only one in ten. We conclude that
most stars arrive on the main sequence surrounded by a disk; this disk then
decays in about 400 Myr. Because (i) the dust particles disappear and must be
replenished on a much shorter time scale and (ii) the collision of
planetesimals is a good source of new dust, we suggest that the rapid decay of
the disks is caused by the destruction and escape of planetesimals. We suggest
that the dissipation of the disk is related to the heavy bombardment phase in
our Solar System. Whether all stars arrive on the main sequence surrounded by a
disk cannot be established: some very young stars do not have a disk. And not
all stars destroy their disk in a similar way: some stars as old as the Sun
still have significant disks.Comment: 16 pages, 9 figures, Astron & Astrophys. in pres
A Sub-Millimeter Search of Nearby Young Stars for Cold Dust: Discovery of Debris Disks around Two Low-Mass Stars
(Abridged) We present results from a JCMT/SCUBA 850 um search for cold dust
around nearby young stars belonging to the beta Pic (t~12 Myr) and the Local
Association (t~50 Myr) moving groups. Unlike most past sub-mm studies, our
sample was chosen on the basis of stellar age. Our observations achieve about
an order of magnitude greater sensitivity in dust mass compared to previous
work in this age range. We detected two of the three M dwarfs in our sample at
850 um, GJ 182 and GJ 803. GJ 182 may also possess a 25 um excess, indicative
of warm dust in the inner few AU of its disk. For GJ 803 (AU Mic), sub-mm
mapping finds that the 850 um emission is unresolved. A non-detection of the CO
3-2 line indicates the system is gas-poor, and the SED suggests the presence of
a large inner disk hole (~17 AU = 1.7 arcsec in radius). These are possible
indications that planets at large separations can form around M dwarfs within
\~10 Myr. In a companion paper (Kalas, Liu & Matthews 2004), we confirm the
existence of a dust disk around GJ 803 using optical coronagraphic imaging.
Given its youthfulness, proximity, and detectability, the GJ 803 disk will be a
valuable system for studying disk, and perhaps planet, formation in great
detail. Overall, sub-mm measurements of debris disks point to a drop in dust
mass by a factor of about 10^3 within the first ~10 Myr, with the subsequent
decline in the masses of sub-mm detected disks consistent with t^{-0.5} to
t^{-1}.Comment: 9 pages, ApJ, in press. Minor changes made to reflect final published
manuscrip
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