A bolometric measurement of the antineutrino mass

High statistics calorimetric measurements of the beta spectrum of 187Re are being performed with arrays of silver perrhenate crystals operated at low temperature. After a modification of the experimental set-up, which allowed to substantially reduce the background of spurious counts and therefore to increase the sensitivity on the electron antineutrino mass, a new measurement with 10 silver perrhenate microbolometers is running since July 2002. The crystals have masses between 250 and 350 micrograms and their average FWHM energy resolution, constantly monitored by means of fluorescence X-rays, is of 28.3 eV at the beta end-point. The Kurie plot collected during 4485 hours x mg effective running time has an end-point energy of 2466.1 +/- 0.8{stat} +/- 1.5 {syst} eV, while the half lifetime of the decay is found to be 43.2 +/- 0.2{stat} +/- 0.1{syst} Gy. These values are the most precise obtained so far for 187Re. From the fit of the Kurie plot we can deduce a value for the squared electron antineutrino mass m(nu)^2 of 147 +/- 237{stat} +/- 90{syst} eV^2. The corresponding 90% C.L. upper limit for m(nu) is 21.7 eV.Comment: 3 pages, 3 figures. Submitted to Phys. Rev. Let

In vivo selection of Plasmodium falciparum parasites carrying the chloroquine-susceptible pfcrt K76 allele after treatment with artemether-lumefantrine in Africa

Background: Artemether-lumefantrine (AL) is a major and highly effective artemisinin-based combination therapy that is becoming increasingly important as a new first-line therapy against Plasmodium falciparum malaria. However, recrudescences occurring after AL treatment have been reported. Identification of drug-specific parasite determinants that contribute to treatment failures will provide important tools for the detection and surveillance of AL resistance. Methods: The findings from a 42-day follow-up efficacy trial in Tanzania that compared AL with sulfadoxinepyrimethamine (SP) were analyzed to identify candidate markers for lumefantrine tolerance/resistance in the chloroquine resistance transporter gene (pfcrt) and multidrug resistance gene 1 (pfmdr1). The findings were corroborated in vitro with genetically modified isogenic P. falciparum parasite lines. Results: Treatment with AL selected for the chloroquine-susceptible pfcrt K76 allele (P \u3c .0001) and, to a lesser extent, the pfmdr1 N86 (P = .048) allele among recurrent infections. These genotypes were not selected during SP treatment. No pfmdr1 gene amplifications were observed. Isogenic pfcrt-modified parasite lines demonstrated a 2-fold increase in susceptibility to lumefantrine, which was directly attributable to the K76T mutation. Conclusions: Our findings suggest that the pfcrt K76T mutation is a drug-specific contributor to enhanced P. falciparum susceptibility to lumefantrine in vivo and in vitro, and they highlight the benefit of using AL in areas affected by chloroquine-resistant P. falciparum malaria. © 2009 by the Infectious Diseases Society of America. All rights reserved

CP-odd Phase Correlations and Electric Dipole Moments

We revisit the constraints imposed by electric dipole moments (EDMs) of nucleons and heavy atoms on new CP-violating sources within supersymmetric theories. We point out that certain two-loop renormalization group corrections induce significant mixing between the basis-invariant CP-odd phases. In the framework of the constrained minimal supersymmetric standard model (CMSSM), the CP-odd invariant related to the soft trilinear A-phase at the GUT scale, theta_A, induces non-trivial and distinct CP-odd phases for the three gaugino masses at the weak scale. The latter give one-loop contributions to EDMs enhanced by tan beta, and can provide the dominant contribution to the electron EDM induced by theta_A. We perform a detailed analysis of the EDM constraints within the CMSSM, exhibiting the reach, in terms of sparticle spectra, which may be obtained assuming generic phases, as well as the limits on the CP-odd phases for some specific parameter points where detailed phenomenological studies are available. We also illustrate how this reach will expand with results from the next generation of experiments which are currently in development.Comment: 31 pages, 21 eps figures; v2: additional remarks on 2-loop threshold corrections and references added; v3: typos corrected, to appear in Phys. Rev.

Conformal Symmetry and Duality between Free Particle, H-atom and Harmonic Oscillator

We establish a duality between the free massless relativistic particle in d dimensions, the non-relativistic hydrogen atom (1/r potential) in (d-1) space dimensions, and the harmonic oscillator in (d-2) space dimensions with its mass given as the lightcone momentum of an additional dimension. The duality is in the sense that the classical action of these systems are gauge fixed forms of the same worldline gauge theory action at the classical level, and they are all described by the same unitary representation of the conformal group SO(d,2) at the quantum level. The worldline action has a gauge symmetry Sp(2) which treats canonical variables (x,p) as doublets and exists only with a target spacetime that has d spacelike dimensions and two timelike dimensions. This spacetime is constrained due to the gauge symmetry, and the various dual solutions correspond to solutions of the constraints with different topologies. For example, for the H-atom the two timelike dimensions X^{0'},X^{0} live on a circle. The model provides an example of how realistic physics can be viewed as existing in a larger covariant space that includes two timelike coordinates, and how the covariance in the larger space unifies different looking physics into a single system.Comment: Latex, 23 pages, minor improvements. In v3 a better gauge choice for u for the H-atom is made; the results are the sam

First-Principles Studies of Hydrogenated Si(111)--7×\times7

The relaxed geometries and electronic properties of the hydrogenated phases of the Si(111)-7$\times$7 surface are studied using first-principles molecular dynamics. A monohydride phase, with one H per dangling bond adsorbed on the bare surface is found to be energetically favorable. Another phase where 43 hydrogens saturate the dangling bonds created by the removal of the adatoms from the clean surface is found to be nearly equivalent energetically. Experimental STM and differential reflectance characteristics of the hydrogenated surfaces agree well with the calculated features.Comment: REVTEX manuscript with 3 postscript figures, all included in uu file. Also available at http://www.phy.ohiou.edu/~ulloa/ulloa.htm

Gauge symmetry in phase space with spin, a basis for conformal symmetry and duality among many interactions

We show that a simple OSp(1/2) worldline gauge theory in 0-brane phase space (X,P), with spin degrees of freedom, formulated for a d+2 dimensional spacetime with two times X^0,, X^0', unifies many physical systems which ordinarily are described by a 1-time formulation. Different systems of 1-time physics emerge by choosing gauges that embed ordinary time in d+2 dimensions in different ways. The embeddings have different topology and geometry for the choice of time among the d+2 dimensions. Thus, 2-time physics unifies an infinite number of 1-time physical interacting systems, and establishes a kind of duality among them. One manifestation of the two times is that all of these physical systems have the same quantum Hilbert space in the form of a unique representation of SO(d,2) with the same Casimir eigenvalues. By changing the number n of spinning degrees of freedom the gauge group changes to OSp(n/2). Then the eigenvalue of the Casimirs of SO(d,2) depend on n and then the content of the 1-time physical systems that are unified in the same representation depend on n. The models we study raise new questions about the nature of spacetime.Comment: Latex, 42 pages. v2 improvements in AdS section. In v3 sec.6.2 is modified; the more general potential is limited to a smaller clas

Plasmon single- and multi-quantum excitation in free metal clusters as seen by photoelectron spectroscopy.

Plasmons are investigated in free nanoscale Na, Mg, and K metal clusters using synchrotron radiation-based x-ray photoelectron spectroscopy. The core levels for which the response from bulk and surface atoms can be resolved are probed over an extended binding energy range to include the plasmon loss features. In all species the features due to fundamental plasmons are identified, and in Na and K also those due to either the first order plasmon overtones or sequential plasmon excitation are observed. These features are discussed in view of earlier results for planar macroscopic samples and free clusters of the same materials

Superiority of Serum Cystatin C Over Creatinine in Prediction of Long-Term Prognosis at Discharge From ICU

MB, BR, CRM and JM have received the Baxter “INVESTIGATOR INITIATED RESEARCH ACUTE CARE GRANT”

A new limit on the permanent electric dipole moment of ^{199}Hg

We present the first results of a new search for a permanent electric dipole moment of the ^{199}Hg atom using a UV laser. Our measurements give d(Hg)= - (1.06 +/- 0.49 +/- 0.40) 10^{-28} e cm. We interpret the result as an upper limit |d(Hg)| < 2.1 10^{-28} e cm (95% C.L.), which sets new constraints on theta_{QCD}, chromo-EDMs of the quarks, and CP violation in Supersymmetric models.Comment: 4 pages, 4 figures, submitted to Phys. Rev. Let

Atomic Parity Nonconservation: Electroweak Parameters and Nuclear Structure

There have been suggestions to measure atomic parity nonconservation (PNC) along an isotopic chain, by taking ratios of observables in order to cancel complicated atomic structure effects. Precise atomic PNC measurements could make a significant contribution to tests of the Standard Model at the level of one loop radiative corrections. However, the results also depend upon certain features of nuclear structure, such as the spatial distribution of neutrons in the nucleus. To examine the sensitivity to nuclear structure, we consider the case of Pb isotopes using various recent relativistic and non-relativistic nuclear model calculations. Contributions from nucleon internal weak structure are included, but found to be fairly negligible. The spread among present models in predicted sizes of nuclear structure effects may preclude using Pb isotope ratios to test the Standard Model at better than a one percent level, unless there are adequate independent tests of the nuclear models by various alternative strong and electroweak nuclear probes. On the other hand, sufficiently accurate atomic PNC experiments would provide a unique method to measure neutron distributions in heavy nuclei.Comment: 44 pages, INT Preprint DOE/ER/40561-050-INT92-00-1