Real, virtual, and other personas in an online collaborative environment

This presentation reports on a study of an unusual online course, which incorporates collaboration across campuses in teaching about evaluation of information technologies. Issues raised by new information technologies are major foci within the course, and also entry points for our study of its implementation.published or submitted for publicationis peer reviewe

A comparative study of the bacterial content of vanilla and chocolate ice cream from two Indianapolis producers

The wide use of ice cream and its high susceptibility to bacterial contamination have stimulated many investigations to determine the extent, the nature and the cause of such contamination and the means of preventing or minimizing it. Inasmuch as the types of organisms are found in ice cream are generally the same as those found in milk or cream, the methods of investigation are basically alike. These methods involve the use of agar plate cultures, direct microscopic observations and biochemical tests. The first two of these techniques were used in this study

A construction of bent functions from plateaued functions

In this presentation, a technique for constructing bent functions from plateaued functions is introduced and analysed. This generalizes earlier techniques for constructing bent from near-bent functions. Using this construction, we obtain a big variety of inequivalent bent functions, some weakly regular and some non-weakly regular. Classes of bent function with some additional properties that enable the construction of strongly regular graphs are constructed, and explicit expressions for bent functions with maximal degree are presented

Practical Low Data-Complexity Subspace-Trail Cryptanalysis of Round-Reduced PRINCE

Subspace trail cryptanalysis is a very recent new cryptanalysis technique, and includes differential, truncated differential, impossible differential, and integral attacks as special cases. In this paper, we consider PRINCE, a widely analyzed block cipher proposed in 2012. After the identification of a 2.5 rounds subspace trail of PRINCE, we present several (truncated differential) attacks up to 6 rounds of PRINCE. This includes a very practical attack with the lowest data complexity of only 8 plaintexts for 4 rounds, which co-won the final round of the PRINCE challenge in the 4-round chosen-plaintext category. The attacks have been verified using a C implementation. Of independent interest, we consider a variant of PRINCE in which ShiftRows and MixLayer operations are exchanged in position. In particular, our result shows that the position of ShiftRows and MixLayer operations influences the security of PRINCE. The same analysis applies to follow-up designs inspired by PRINCE

Collective T- and P- Odd Electromagnetic Moments in Nuclei with Octupole Deformations

Parity and time invariance violating forces produce collective P- and T- odd moments in nuclei with static octupole deformation. Collective Schiff moment, electric octupole and dipole and also magnetic quadrupole appear due to the mixing of rotational levels of opposite parity and can exceed single-particle moments by more than a factor of 100. This enhancement is due to two factors, the collective nature of the intrinsic moments and the small energy separation between members of parity doublets. The above moments induce T- and P- odd effects in atoms and molecules. Experiments with such systems may improve substantially the limits on time reversal violation.Comment: 9 pages, Revte

An affect misattribution pathway to perceptions of intrinsic reward

Intrinsic rewards are typically thought to stem from an activity's inherent properties and not from separable rewards one receives from it. Yet, people may not consciously notice or remember all the subtle external rewards that correspond with an activity and may misattribute some directly to the activity itself. We propose that perceptions of intrinsic reward can often be byproducts of misattributed causal inference, and present some initial evidence that perceptions of intrinsic reward can in fact increase when words pertaining to an activity are subtly paired with pleasant context cues. Importantly, these effects follow classic boundary conditions of both misattribution and intrinsic motivation; insofar as they were extinguished when participants could make a proper source attribution and/or when the activity became associated with a blatant external reward. We further propose a distinction can be made between authentically "intrinsic" rewards and the illusion of intrinsic rewards caused by misattributed positive affect

Nearby Doorways, Parity Doublets and Parity Mixing in Compound Nuclear States

We discuss the implications of a doorway state model for parity mixing in compound nuclear states. We argue that in order to explain the tendency of parity violating asymmetries measured in $^{233}$Th to have a common sign, doorways that contribute to parity mixing must be found in the same energy neighbourhood of the measured resonance. The mechanism of parity mixing in this case of nearby doorways is closely related to the intermediate structure observed in nuclear reactions in which compound states are excited. We note that in the region of interest ($^{233}$Th) nuclei exhibit octupole deformations which leads to the existence of nearby parity doublets. These parity doublets are then used as doorways in a model for parity mixing. The contribution of such mechanism is estimated in a simple model.Comment: 11 pages, REVTE

Nuclear Octupole Correlations and the Enhancement of Atomic Time-Reversal Violation

We examine the time-reversal-violating nuclear ``Schiff moment'' that induces electric dipole moments in atoms. After presenting a self-contained derivation of the form of the Schiff operator, we show that the distribution of Schiff strength, an important ingredient in the ground-state Schiff moment, is very different from the electric-dipole-strength distribution, with the Schiff moment receiving no strength from the giant dipole resonance in the Goldhaber-Teller model. We then present shell-model calculations in light nuclei that confirm the negligible role of the dipole resonance and show the Schiff strength to be strongly correlated with low-lying octupole strength. Next, we turn to heavy nuclei, examining recent arguments for the strong enhancement of Schiff moments in octupole-deformed nuclei over that of 199Hg, for example. We concur that there is a significant enhancement while pointing to effects neglected in previous work (both in the octupole-deformed nuclides and 199Hg) that may reduce it somewhat, and emphasizing the need for microscopic calculations to resolve the issue. Finally, we show that static octupole deformation is not essential for the development of collective Schiff moments; nuclei with strong octupole vibrations have them as well, and some could be exploited by experiment.Comment: 25 pages, 4 figures embedded in tex

Comprehensive comparison between azacytidine and decitabine treatment in an acute myeloid leukemia cell line

Azacytidine (AzaC) and decitabine (AzadC) are cytosine analogs that covalently trap DNA methyltransferases, which place the important epigenetic mark 5-methyl-2’-deoxycytidine by methylating 2’-deoxycytidine (dC) at the C5 position. AzaC and AzadC are used in the clinic as antimetabolites to treat myelodysplastic syndrome and acute myeloid leukemia and are explored against other types of cancer. Although their principal mechanism of action is known, the downstream effects of AzaC and AzadC treatment are not well understood and the cellular prerequisites that determine sensitivity toward AzaC and AzadC remain elusive. Here, we investigated the effects and phenotype of AzaC and AzadC exposure on the acute myeloid leukemia cell line MOLM-13. We found that while AzaC and AzadC share many effects on the cellular level, including decreased global DNA methylation, increased formation of DNA double-strand breaks, transcriptional downregulation of important oncogenes and similar changes on the proteome level, AzaC failed in contrast to AzadC to induce apoptosis efficiently in MOLM-13. The only cellular marker that correlated with this clear phenotypical outcome was the level of hydroxy-methyl-dC, an additional epigenetic mark that is placed by TET enzymes and repressed in cancer cells. Whereas AzadC increased hmdC substantially in MOLM-13, AzaC treatment did not result in any increase at all. This suggests that hmdC levels in cancer cells should be monitored as a response toward AzaC and AzadC and considered as a biomarker to judge whether AzaC or AzadC treatment leads to cell death in leukemic cells