Directedness of Information Flow in Mobile Phone Communication Networks

Without having direct access to the information that is being exchanged, traces of information flow can be obtained by looking at temporal sequences of user interactions. These sequences can be represented as causality trees whose statistics result from a complex interplay between the topology of the underlying (social) network and the time correlations among the communications. Here, we study causality trees in mobile-phone data, which can be represented as a dynamical directed network. This representation of the data reveals the existence of super-spreaders and super-receivers. We show that the tree statistics, respectively the information spreading process, are extremely sensitive to the in-out degree correlation exhibited by the users. We also learn that a given information, e.g., a rumor, would require users to retransmit it for more than 30 hours in order to cover a macroscopic fraction of the system. Our analysis indicates that topological node-node correlations of the underlying social network, while allowing the existence of information loops, they also promote information spreading. Temporal correlations, and therefore causality effects, are only visible as local phenomena and during short time scales. Consequently, the very idea that there is (intentional) information spreading beyond a small vecinity is called into question. These results are obtained through a combination of theory and data analysis techniques

A search for methane in the atmosphere of GJ 1214b via GTC narrow-band transmission spectrophotometry

We present narrow-band photometric measurements of the exoplanet GJ 1214b using the 10.4 m Gran Telescopio Canarias and the Optical System for Imaging and low Resolution Integrated Spectroscopy instrument. Using tuneable filters, we observed a total of five transits, three of which were observed at two wavelengths nearly simultaneously, producing a total of eight individual light curves, six of these probed the possible existence of a methane absorption feature in the 8770–8850 Å region at high resolution. We detect no increase in the planet-to-star radius ratio across the methane feature with a change in radius ratio of ΔR = -0.0007 ± 0.0017 corresponding to a scaleheight (H) change of −0.5 ± 1.2H across the methane feature, assuming a hydrogen-dominated atmosphere. We find that a variety of water and cloudy atmospheric models fit the data well, but find that cloud-free models provide poor fits. These observations support a flat transmission spectrum resulting from the presence of a high-altitude haze or a water-rich atmosphere, in agreement with previous studies. In this study, the observations are pre-dominantly limited by the photometric quality and the limited number of data points (resulting from a long observing cadence), which make the determination of the systematic noise challenging. With tuneable filters capable of high-resolution measurements (R ≈ 600–750) of narrow absorption features, the interpretation of our results are also limited by the absence of high-resolution methane models below 1 μm

Chronic Obstructive Pulmonary Disease and Lung Cancer: Underlying Pathophysiology and New Therapeutic Modalities

Chronic obstructive pulmonary disease (COPD) and lung cancer are major lung diseases affecting millions worldwide. Both diseases have links to cigarette smoking and exert a considerable societal burden. People suffering from COPD are at higher risk of developing lung cancer than those without, and are more susceptible to poor outcomes after diagnosis and treatment. Lung cancer and COPD are closely associated, possibly sharing common traits such as an underlying genetic predisposition, epithelial and endothelial cell plasticity, dysfunctional inflammatory mechanisms including the deposition of excessive extracellular matrix, angiogenesis, susceptibility to DNA damage and cellular mutagenesis. In fact, COPD could be the driving factor for lung cancer, providing a conducive environment that propagates its evolution. In the early stages of smoking, body defences provide a combative immune/oxidative response and DNA repair mechanisms are likely to subdue these changes to a certain extent; however, in patients with COPD with lung cancer the consequences could be devastating, potentially contributing to slower postoperative recovery after lung resection and increased resistance to radiotherapy and chemotherapy. Vital to the development of new-targeted therapies is an in-depth understanding of various molecular mechanisms that are associated with both pathologies. In this comprehensive review, we provide a detailed overview of possible underlying factors that link COPD and lung cancer, and current therapeutic advances from both human and preclinical animal models that can effectively mitigate this unholy relationship

Measurement of the Depth of Maximum of Extensive Air Showers above 10^(18) eV

We describe the measurement of the depth of maximum, X_(max), of the longitudinal development of air showers induced by cosmic rays. Almost 4000 events above 10^(18) eV observed by the fluorescence detector of the Pierre Auger Observatory in coincidence with at least one surface detector station are selected for the analysis. The average shower maximum was found to evolve with energy at a rate of (106_(-21)^(+35)) g/cm^2/decade below 10^(18:24±0.05) eV, and (24±3) g/cm^ 2=decade above this energy. The measured shower-to-shower fluctuations decrease from about 55 to 26 g/cm^2. The interpretation of these results in terms of the cosmic ray mass composition is briefly discussed

Ion–Aerosol Flux Coefficients and the Steady-State Charge Distribution of Aerosols in a Bipolar Ion Environment

Fuchs’ theory, as corrected by Hoppel and Frick, is widely used to compute flux coefficients of ions to aerosol particles and the resultant charge distribution. We have identified approximations made in previous works that limit the theory’s accuracy. Hoppel and Frick used two characteristic speeds or kinetic energies to calculate the flux coefficients of ions to aerosol particles in lieu of an average of the flux coefficients over the Maxwell–Boltzmann distribution of ion speeds. In the present work, we show that this approximation artificially reduces the number of multiply charged particles. Ion capture may be enhanced by three-body trapping, a process wherein an ion has a collision with a neutral gas molecule and loses sufficient kinetic energy to be captured by the particle. The gas kinetic theory approach to three-body trapping has been refined to better account for the collision between the ion and a neutral gas molecule within the potential presented by the particle. Approximations to the calculation of energy losses and the probability of ion capture have been relaxed. The possibility that an image charge may be induced on the ion as well as on the particle is allowed. While the previous work was limited to electrically conductive particles, both the ion and the particle are allowed to have any dielectric constant in the present work, and the finite size of the ions is taken into account when calculating minimum capture radii for the ion–particle interactions. The resulting ion flux coefficients differ from previous results both in the low nanometer regime and in the continuum regime. We explore the influence of key parameters on the charge distribution, including dielectric constant, temperature, and pressure, to understand how operating conditions may affect the interpretation of differential mobility analyzer measurements of particle size distributions. Finally, an empirical expression for the new charge distribution is given to facilitate rapid calculations

Variable jets with non-top hat ejection cross sections: a model for the knots of the HH 34 jet

We compute axisymmetric, single-sinusoidal mode variable ejection models with a non-top hat ejection velocity cross section. We find that for decreasing edge-to-center velocity ratios one obtains internal working surfaces with progressively more extended bow shock wings. These wings produce [S H] emission which partially fills in the inter-knot regions in predicted intensity maps. We then compute 3-mode models (with parameters appropriate for the HH 34 jet), and compare predicted intensity maps with archival HST images of HH 34. We find that a model with a moderate edge-to-center velocity ratio produces knot structures with morphologies and time-variabilites with clear similarities to the observations of HH 34

Generating tool-path with smooth posture change for five-axis sculptured surface machining based on cutter's accessibility map

10.1007/s00170-010-2849-2International Journal of Advanced Manufacturing Technology535-8699-709IJAT

An eutrophication index for lowland sandy rivers in Mediterranean coastal climatic regions of Southern Africa

The eutrophication of waterways has become an endemic global problem. Nutrient enrichment from agriculture activities and waste water treatment plants are major drivers, but it remains unclear how lowland sandy rivers respond to eutrophication. The objective of this study was the development and verification of eutrophication index for sandy rivers (EISR) to prioritize nutrient enrichment river stretches caused by different land use activities that include point and nonpoint sources of nutrient enrich water. The Berg River drainage system in South Africa served as a case study area for this purpose during the dry seasons (December and January) of 2015 and 2016. In the initial EISR development phase, periphyton, benthic biomass (chl-a mg m−2), and macroinvertebrate families were employed as benthic bioindicators of river bedforms, whereas in the second phase, physicochemical and abiotic variables were used as target indicator. Using a weight of support approach, the site receiving sewage effluent was categorize as heavily polluted whereas sites impacted by agriculture land use activities were polluted. The EISR that focuses strongly on benthic bioindicators, which are close to the transfer of nutrients and energy in the food web, showed a distinct difference between river bedform impacted by sewage effluent and agriculture none point source. A maximum benthic algae biomass of 110 mg m−2 chl-a was recorded with higher sediment orthophosphate concentration at sewage-impacted sites. The outcome of the proposed EISR showed that it can be employed as a decision support tool for eutrophication management of sandy rivers.Fil: Oberholster, Paul Johan. Natural Resources and the Environment; Sudáfrica. University of Stellenbosch; Sudáfrica. University of the Western Cape; SudáfricaFil: Madlala, Tebogo. Natural Resources and the Environment; Sudáfrica. University of the Western Cape; SudáfricaFil: Blettler, Martin Cesar Maria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto Nacional de Limnología. Universidad Nacional del Litoral. Instituto Nacional de Limnología; ArgentinaFil: Amsler, Mario Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto Nacional de Limnología. Universidad Nacional del Litoral. Instituto Nacional de Limnología; ArgentinaFil: Eberle Folmer, Eliana Gisel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto Nacional de Limnología. Universidad Nacional del Litoral. Instituto Nacional de Limnología; ArgentinaFil: Botha, Anna María. University of Stellenbosch; Sudáfric