JAKARTA, INDONESIA: THE ECONOMICS OF WATER AND WASTE

Jakarta's main streets are landscaped, manicured, and modern. Off these streets, however, the environment is that of an overgrown village. Compared to other Asian cities, Jakarta's drinking water, sewerage treatment, solid waste disposal, and general environment are seriously deficient. This case study briefly outlines the deficiencies. Less than one-fourth the residents have piped water. Almost no one is attached to a sewer. One-third of the city's solid waste never reaches the landfill. The source of the problems is historical -- for a long time, the problems of this rapidly growing city were not adequately addressed. And the problem has become worse in recent years by the policymakers' concern with providing first-class service to all, despite the fact that budgetary shortcomings prevent them from extending such service beyond the richest households. As a result, the poor often receive no public services and must resort to expensive private provision or do without. The principal lesson from and for Jakarta is that policymakers must give more attention to providing less-than-first-class but affordable services to the poor.Environmental Economics and Policy,

Does microneedling with 5% minoxidil offer added advantage for treatment of androgenetic alopecia in comparison to use of topical 5% minoxidil alone?

Background: Androgenetic alopecia is the most common cause of chronic hair loss. The FDA approved treatment for male androgenetic alopecia are Finasteride and Minoxidil. But many patients do not respond to these medications. Microneedling is a recent modality that releases several growth factors and enhances penetration of minoxidil, thereby promoting hair growth.Methods: 60 patients, aged 21-40 years, with androgenetic alopecia were divided into 2 groups. In group A, patients were subjected to microneedling twice monthly, immediately followed by application of topical 5% minoxidil solution over the scalp and then 1 ml twice daily. In group B, patients were treated with application of 1ml of topical 5% minoxidil solution over the scalp twice daily. The results were evaluated based on patient’s and physician’s assessment based on the standardized 7-point evaluation scale.Results: Patients in group A showed statistically significant improvement (p value<0.05) compared to group B. Headache and erythema were the most common side effects encountered in both the groups.Conclusions: Microneedling with 5% minoxidil is a safe, simple and cost-effective modality and is a promising treatment option for patients with androgenetic alopecia. It showed much better results when compared to use of topical 5% minoxidil solution alone

Localization of deformed wing virus (DWV) in the brains of the honeybee, Apis mellifera Linnaeus

<p>Abstract</p> <p>Background</p> <p>Deformed wing virus (DWV) is a positive-strand RNA virus that infects European honeybees (<it>Apis mellifera </it>L.) and has been isolated from the brains of aggressive bees in Japan. DWV is known to be transmitted both vertically and horizontally between bees in a colony and can lead to both symptomatic and asymptomatic infections in bees. In environmentally stressful conditions, DWV can contribute to the demise of a honeybee colony. The purpose of the current study is to identify regions within the brains of honeybees where DWV replicates using <it>in-situ </it>hybridization.</p> <p>Results</p> <p><it>In-situ </it>hybridizations were conducted with both sense and antisense probes on the brains of honeybees that were positive for DWV as measured by real-time RT-PCR. The visual neuropils demonstrated detectable levels of the DWV positive-strand genome. The mushroom bodies and antenna lobe neuropils also showed the presence of the viral genome. Weaker staining with the sense probe in the same regions demonstrates that the antigenome is also present and that the virus is actively replicating in these regions of the brain.</p> <p>Conclusion</p> <p>These results demonstrate that in bees infected with DWV the virus is replicating in critical regions of the brain, including the neuropils responsible for vision and olfaction. Therefore DWV infection of the brain could adversely affect critical sensory functions and alter normal bee behavior.</p

When is a hydrological model sufficiently calibrated to depict flow preferences of riverine species?

Riverine species have adapted to their environment, particularly to the hydrological regime. Hydrological models and the knowledge of species preferences are used to predict the impact of hydrological changes on species. Inevitably, hydrological model performance impacts how species are simulated. From the example of macroinvertebrates in a lowland and a mountainous catchment, we investigate the impact of hydrological model performance and the choice of the objective function based on a set of 36 performance metrics for predicting species occurrences. Besides species abundance, we use the simulated community structure for an ecological assessment as applied for the Water Framework Directive. We investigate when a hydrological model is sufficiently calibrated to depict species abundance. For this, we postulate that performance is not sufficient when ecological assessments based on the simulated hydrology are significantly different (analysis of variance, p < .05) from the ecological assessments based on observations. The investigated range of hydrological model performance leads to considerable variability in species abundance in the two catchments. In the mountainous catchment, links between objective functions and the ecological assessment reveal a stronger dependency of the species on the discharge regime. In the lowland catchment, multiple stressors seem to mask the dependence of the species on discharge. The most suitable objective functions to calibrate the model for species assessments are the ones that incorporate hydrological indicators used for the species prediction

Climate model variability leads to uncertain predictions of the future abundance of stream macroinvertebrates

Climate change has the potential to alter the flow regimes of rivers and consequently affect the taxonomic and functional diversity of freshwater organisms. We modeled future flow regimes for the 2050 and 2090 time horizons and tested how flow regimes impact the abundance of 150 macroinvertebrate species and their functional trait compositions in one lowland river catchment (Treene) and one mountainous river catchment (Kinzig) in Europe. We used all 16 global circulation models (GCMs) and regional climate models (RCMs) of the CORDEX dataset under the RCP 8.5 scenario to calculate future river flows. The high variability in relative change of flow among the 16 climate models cascaded into the ecological models and resulted in substantially different predicted abundance values for single species. This variability also cascades into any subsequent analysis of taxonomic or functional freshwater biodiversity. Our results showed that flow alteration effects are different depending on the catchment and the underlying species pool. Documenting such uncertainties provides a basis for the further assessment of potential climate-change impacts on freshwater taxa distributions