1,823 research outputs found

    Slow equivariant lump dynamics on the two sphere

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    The low-energy, rotationally equivariant dynamics of n CP^1 lumps on S^2 is studied within the approximation of geodesic motion in the moduli space of static solutions. The volume and curvature properties of this moduli space are computed. By lifting the geodesic flow to the completion of an n-fold cover of the moduli space, a good understanding of nearly singular lump dynamics within this approximation is obtained.Comment: 12 pages, 3 figure

    Evaluation of Vascular Control Mechanisms Utilizing Video Microscopy of Isolated Resistance Arteries of Rats

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    This protocol describes the use of in vitro television microscopy to evaluate vascular function in isolated cerebral resistance arteries (and other vessels), and describes techniques for evaluating tissue perfusion using Laser Doppler Flowmetry (LDF) and microvessel density utilizing fluorescently labeled Griffonia simplicifolia (GS1) lectin. Current methods for studying isolated resistance arteries at transmural pressures encountered in vivo and in the absence of parenchymal cell influences provide a critical link between in vivo studies and information gained from molecular reductionist approaches that provide limited insight into integrative responses at the whole animal level. LDF and techniques to selectively identify arterioles and capillaries with fluorescently-labeled GS1 lectin provide practical solutions to enable investigators to extend the knowledge gained from studies of isolated resistance arteries. This paper describes the application of these techniques to gain fundamental knowledge of vascular physiology and pathology in the rat as a general experimental model, and in a variety of specialized genetically engineered designer rat strains that can provide important insight into the influence of specific genes on important vascular phenotypes. Utilizing these valuable experimental approaches in rat strains developed by selective breeding strategies and new technologies for producing gene knockout models in the rat, will expand the rigor of scientific premises developed in knockout mouse models and extend that knowledge to a more relevant animal model, with a well understood physiological background and suitability for physiological studies because of its larger size

    Out-of-plane behavior of one-way spanning unreinforced masonry walls

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    An analytical model is developed to describe the out-of-plane response of one-way spanning unreinforced masonry (URM) walls by investigating the effects of various parameters. Horizontal crack height, masonry compressive strength, and diaphragm support stiffness properties are assumed as variables, and sensitivity analyses are performed to study the influence of these parameters on the cracked wall characteristic behavior. The parametric studies show that crack height significantly influences wall stability by affecting both the instability displacement and the wall lateral resistance. The reduction in cracked wall lateral resistance and in the instability displacement caused by finite masonry compressive strength is shown to be significantly amplified by the applied overburden. A study using the typical configuration of flexible diaphragms and URM walls indicates that the wall top support flexibility does not significantly influence cracked wall out-of-plane response. An existing simplified wall behavioral model is improved, and a procedure is proposed for calculation of the wall out-of-plane response envelope.Hossein Derakhshan; Michael C. Griffith; and Jason M. Ingha

    School-based curriculum development in Scotland: Curriculum policy and enactment

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    Recent worldwide trends in curriculum policy have re-emphasised the role of teachers in school-based curriculum development. Scotland’s Curriculum for Excellence is typical of these trends, stressing that teachers are agents of change. This paper draws upon empirical data to explore school-based curriculum development in response to Curriculum for Excellence. We focus on two case studies – secondary schools within a single Scottish local education authority. In the paper we argue that the nature and extent of innovation in schools is dependent upon teachers being able to make sense of often complex and confusing curriculum policy, including the articulation of a clear vision about what such policy means for education within each school

    Spectral Analysis of Guanine and Cytosine Fluctuations of Mouse Genomic DNA

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    We study global fluctuations of the guanine and cytosine base content (GC%) in mouse genomic DNA using spectral analyses. Power spectra S(f) of GC% fluctuations in all nineteen autosomal and two sex chromosomes are observed to have the universal functional form S(f) \sim 1/f^alpha (alpha \approx 1) over several orders of magnitude in the frequency range 10^-7< f < 10^-5 cycle/base, corresponding to long-ranging GC% correlations at distances between 100 kb and 10 Mb. S(f) for higher frequencies (f > 10^-5 cycle/base) shows a flattened power-law function with alpha < 1 across all twenty-one chromosomes. The substitution of about 38% interspersed repeats does not affect the functional form of S(f), indicating that these are not predominantly responsible for the long-ranged multi-scale GC% fluctuations in mammalian genomes. Several biological implications of the large-scale GC% fluctuation are discussed, including neutral evolutionary history by DNA duplication, chromosomal bands, spatial distribution of transcription units (genes), replication timing, and recombination hot spots.Comment: 15 pages (figures included), 2 figure

    MOVEMENT OF ORGANIC MATERIALS IN PLANTS: A CORRECTION

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    Case study:shipping trend estimation and prediction via multiscale variance stabilisation

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    <p>Shipping and shipping services are a key industry of great importance to the economy of Cyprus and the wider European Union. Assessment, management and future steering of the industry, and its associated economy, is carried out by a range of organisations and is of direct interest to a number of stakeholders. This article presents an analysis of shipping credit flow data: an important and archetypal series whose analysis is hampered by rapid changes of variance. Our analysis uses the recently developed data-driven Haar–Fisz transformation that enables accurate trend estimation and successful prediction in these kinds of situation. Our trend estimation is augmented by bootstrap confidence bands, new in this context. The good performance of the data-driven Haar–Fisz transform contrasts with the poor performance exhibited by popular and established variance stabilisation alternatives: the Box–Cox, logarithm and square root transformations.</p

    Dynamic Critical Behavior of the Swendsen-Wang Algorithm: The Two-Dimensional 3-State Potts Model Revisited

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    We have performed a high-precision Monte Carlo study of the dynamic critical behavior of the Swendsen-Wang algorithm for the two-dimensional 3-state Potts model. We find that the Li-Sokal bound (τint,Econst×CH\tau_{int,E} \geq const \times C_H) is almost but not quite sharp. The ratio τint,E/CH\tau_{int,E} / C_H seems to diverge either as a small power (0.08\approx 0.08) or as a logarithm.Comment: 35 pages including 3 figures. Self-unpacking file containing the LaTeX file, the needed macros (epsf.sty, indent.sty, subeqnarray.sty, and eqsection.sty) and the 3 Postscript figures. Revised version fixes a normalization error in \xi (with many thanks to Wolfhard Janke for finding the error!). To be published in J. Stat. Phys. 87, no. 1/2 (April 1997

    Characterization of the Crab Pulsar's Timing Noise

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    We present a power spectral analysis of the Crab pulsar's timing noise, mainly using radio measurements from Jodrell Bank taken over the period 1982-1989. The power spectral analysis is complicated by nonuniform data sampling and the presence of a steep red power spectrum that can distort power spectra measurement by causing severe power ``leakage''. We develop a simple windowing method for computing red noise power spectra of uniformly sampled data sets and test it on Monte Carlo generated sample realizations of red power-law noise. We generalize time-domain methods of generating power-law red noise with even integer spectral indices to the case of noninteger spectral indices. The Jodrell Bank pulse phase residuals are dense and smooth enough that an interpolation onto a uniform time series is possible. A windowed power spectrum is computed revealing a periodic or nearly periodic component with a period of about 568 days and a 1/f^3 power-law noise component with a noise strength of 1.24 +/- 0.067 10^{-16} cycles^2/sec^2 over the analysis frequency range 0.003 - 0.1 cycles/day. This result deviates from past analyses which characterized the pulse phase timing residuals as either 1/f^4 power-law noise or a quasiperiodic process. The analysis was checked using the Deeter polynomial method of power spectrum estimation that was developed for the case of nonuniform sampling, but has lower spectral resolution. The timing noise is consistent with a torque noise spectrum rising with analysis frequency as f implying blue torque noise, a result not predicted by current models of pulsar timing noise. If the periodic or nearly periodic component is due to a binary companion, we find a companion mass > 3.2 Earth masses.Comment: 53 pages, 9 figures, submitted to MNRAS, abstract condense
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