88 research outputs found
Reversible Control of Magnetic Interactions by Electric Field in a Single Phase Material
Intrinsic magnetoelectric coupling describes the interaction between magnetic
and electric polarization through an inherent microscopic mechanism in a single
phase material. This phenomenon has the potential to control the magnetic state
of a material with an electric field, an enticing prospect for device
engineering. We demonstrate 'giant' magnetoelectric cross-field control in a
single phase rare earth titanate film. In bulk form, EuTiO3 is
antiferromagnetic. However, both anti and ferromagnetic interactions coexist
between different nearest neighbor europium ions. In thin epitaxial films,
strain can be used to alter the relative strength of the magnetic exchange
constants. Here, we not only show that moderate biaxial compression
precipitates local magnetic competition, but also demonstrate that the
application of an electric field at this strain state, switches the magnetic
ground state. Using first principles density functional theory, we resolve the
underlying microscopic mechanism resulting in the EuTiO3 G-type magnetic
structure and illustrate how it is responsible for the 'giant' cross-field
magnetoelectric effect
Polymeric nanocapsules prevent oxidation of core-loaded molecules: evidence based on the effects of docosahexaenoic acid and neuroprostane on breast cancer cells proliferation
Bioprocessing strategies for the large-scale production of human mesenchymal stem cells: a review
Ten Months of Digital Reading
We address digital reading practices in Russia analyzing 10 months of logging data from a commercial ebook mobile app.We describe the data and focus on three aspects: reading schedule, reading speed, and book abandonment. The exploratory study proves a high potential of the
data and proposed approach.Peer Reviewe
Crystal structure of a class III adenylyl cyclase like ATP binding protein from Pseudomonas aeruginosa
On the challenges of deploying an unusual high performance hybrid object/file parallel storage system in JASMIN
Resonant magnetic x-ray scattering from terbium
Resonant magnetic x-ray scattering from Tb in the spiral phase is studied in great detail. Polarization analysis in the sigma-sigma' and sigma-pi' channels has been performed for magnetic (0, 0, l +/- tau) satellite reflections over the accessible wavevector range Q = 1.9-6.5 angstrom(-1). A characteristic splitting of the resonance signal as a function of energy has been observed at the L-II as well as at the L-III absorption edge. The shape of the resonance depends on Q and is different for the two edges. Up to three components were observed with a separation in energy between 3.3 and 4.9 eV, compared to a core hole lifetime broadening of 2.5 eV, which is in agreement with the density of states in Tb metal
Analysis of Bone Scans in Various Tumor Entities Using a Deep-Learning-Based Artificial Neural Network Algorithm—Evaluation of Diagnostic Performance
The bone scan index (BSI), initially introduced for metastatic prostate cancer, quantifies the osseous tumor load from planar bone scans. Following the basic idea of radiomics, this method incorporates specific deep-learning techniques (artificial neural network) in its development to provide automatic calculation, feature extraction, and diagnostic support. As its performance in tumor entities, not including prostate cancer, remains unclear, our aim was to obtain more data about this aspect. The results of BSI evaluation of bone scans from 951 consecutive patients with different tumors were retrospectively compared to clinical reports (bone metastases, yes/no). Statistical analysis included entity-specific receiver operating characteristics to determine optimized BSI cut-off values. In addition to prostate cancer (cut-off = 0.27%, sensitivity (SN) = 87%, specificity (SP) = 99%), the algorithm used provided comparable results for breast cancer (cut-off 0.18%, SN = 83%, SP = 87%) and colorectal cancer (cut-off = 0.10%, SN = 100%, SP = 90%). Worse performance was observed for lung cancer (cut-off = 0.06%, SN = 63%, SP = 70%) and renal cell carcinoma (cut-off = 0.30%, SN = 75%, SP = 84%). The algorithm did not perform satisfactorily in melanoma (SN = 60%). For most entities, a high negative predictive value (NPV ≥ 87.5%, melanoma 80%) was determined, whereas positive predictive value (PPV) was clinically not applicable. Automatically determined BSI showed good sensitivity and specificity in prostate cancer and various other entities. Particularly, the high NPV encourages applying BSI as a tool for computer-aided diagnostic in various tumor entities
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