Specifications and programs for computer software validation

Three software products developed during the study are reported and include: (1) FORTRAN Automatic Code Evaluation System, (2) the Specification Language System, and (3) the Array Index Validation System

Assessing emissions levels and costs associated with climate and air pollution policies in South Africa

Affordable energy supply and reductions in emissions of local air pollution and greenhouse gases are each important aspects of South Africa's goals. Many traditional solutions, however, work in contradiction to one another. This work investigates effects on estimated emissions and costs of mitigation strategies using the Greenhouse Gas and Air Pollution Interaction Synergies (GAINS) model to identify policies that satisfy multiple goals. Eight scenarios that describe air pollution control options and mixes of energy production technologies are implemented in GAINS, which quantifies country-wide air pollution and greenhouse emissions and costs of controls. Emissions and costs trajectories are compared to the business as usual case, which projects CO2 emissions to increase by 60% by 2050 compared to 2015. Results show that replacing all coal generation with renewables reduces CO2 emissions in 2050 by 8% compared to 2015, and that aggressive policy targeting the whole energy sector reduces CO2 emissions in 2050 by 40%. GAINS is used to show co-benefits and tradeoffs of each scenario, such as reductions in emissions control costs that accompany a switch to renewables. The approach provides supporting evidence for policies that exploit co-benefits and avoid contradictions by assessing multiple aspects of the energy sector within the integrated framework provided by the GAINS modeling platform

A policy review of synergies and trade-offs in South African climate change mitigation and air pollution control strategies

Climate change mitigation and air quality management are mostly addressed separately in South African legal acts and policies. This approach is not always coherent, especially in the context of other serious issues South Africa is facing, suh as poverty alleviation. Policies implemented to mitigate climate change might increase negative health affects due to unanticipated outcomes (e.g. increased local air pollution), and these indirect consequences must therefore be taken into account when devising mitigation strategies. However, greenhouse gas mitigation policies can also have co-benefits and positive impacts on local air pollution. An evidence-based approach that takes into account greenhouse gas emissions, ambient air pollutants, economic factors (affordability, cost optimisation), social factors (poverty alleviations, public health benefits), and political acceptability is needed tackle these challenges. A proposal is made that use of an integrated climate/air pollution techno-economic optimising model, such as the Greenhouse Gas and Air Pollution Synergies (GAINS) model, may provide a rational decision support tool to guide policy makers into effective strategies for combined Climate Change and Air Quality mitigation measures

Preconceptional genetic carrier testing and the commercial offer directly-to-consumers

Recently, a number of commercial companies are offering preconceptional carrier tests directly-to-consumers. This offer raises a number of concerns and issues above and beyond those encountered with preconceptional tests offered within the traditional health care setting. In order to bring some of these issues to light and to initiate dialogue on this topic, this article discusses the following issues: the current offer of preconceptional carrier tests (until the end of 2010) through online commercial companies; the implications for the informed consent procedure and the need for good information; the need for medical supervision and follow-up; and the appropriate use of existing resources. The article concludes with some reflections about the potential sustainability of the offer of preconceptional carrier tests directly-to-consumers

Fortran Automatic Code Evaluation System (FACES)

Software package takes as input FORTRAN program which may contain many modules (subroutines and functions). Main parts: (1) FORTRAN front end gathers information about input program and (2) set of routines organized as diagnostic package evaluates information and prints warning messages concerning actual or potential errors

Automation and data processing with the immucor Galileo (R) system in a university blood bank

Background: The implementation of automated techniques improves the workflow and quality of immuno-hematological results. The workflows of our university blood bank were reviewed during the implementation of an automated immunohematological testing system. Methods: Work impact of blood grouping and subgrouping, cross- matching and antibody search using the Immucor Galileo system was compared to the previous used standard manual and semi- automated methods. Results: The redesign of our workflow did not achieve a significant reduction of the specimen's working process time, the operator's time however was reduced by 23%. Corresponding results were achieved for blood grouping, Rhesus typing, antibody screen and for autocontrol when changing from two semi- automated to the Galileo system. Because of the higher sensitivity of the Immucor antibody detection system, the rate of the initial positive antibody screens rose from 4 to 6% Conclusion: The Immucor Galileo system automates routine blood bank testing with high reliability, specificity and higher sensitivity compared to our previous used standard manual and semi- automated methods

Spelling in adolescents with dyslexia: errors and modes of assessment

In this study we focused on the spelling of high-functioning students with dyslexia. We made a detailed classification of the errors in a word and sentence dictation task made by 100 students with dyslexia and 100 matched control students. All participants were in the first year of their bachelor’s studies and had Dutch as mother tongue. Three main error categories were distinguished: phonological, orthographic, and grammatical errors (on the basis of morphology and language-specific spelling rules). The results indicated that higher-education students with dyslexia made on average twice as many spelling errors as the controls, with effect sizes of d ≥ 2. When the errors were classified as phonological, orthographic, or grammatical, we found a slight dominance of phonological errors in students with dyslexia. Sentence dictation did not provide more information than word dictation in the correct classification of students with and without dyslexia

Bounds on transverse momentum dependent distribution and fragmentation functions

We give bounds on the distribution and fragmentation functions that appear at leading order in deep inelastic 1-particle inclusive leptoproduction or in Drell-Yan processes. These bounds simply follow from positivity of the defining matrix elements and are an important guidance in estimating the magnitude of the azimuthal and spin asymmetries in these processes.Comment: 5 pages, Revtex, 3 Postscript figures, version with minor changes, to be published in Physical Review Letter