Products from the high temperature pyrolysis of RDF at slow and rapid heating rates

The high-temperature pyrolysis behaviour of a sample of refuse derived fuel (RDF) as a model of municipal solid waste (MSW) was investigated in a horizontal tubular reactor between 700 and 900 °C, at varying heating rates, and at an extended vapour residence time. Experiments were designed to evaluate the influence of process conditions on gas yields as well as gas and oil compositions. Pyrolysis of RDF at 800 °C and at rapid heating rate resulted in the gas yield with the highest CV of 24.8 MJ m-3 while pyrolysis to 900 °C at the rapid heating rate generated the highest gas yield but with a lower CV of 21.3 MJ m-3. A comparison of the effect of heating rates on oil products revealed that the oil from slow pyrolysis, contained higher yields of more oxygenates, alkanes (C8-C39) and alkenes (C8-C20), while the oil from rapid pyrolysis contained more aromatics, possibly due to the promotion of Diels-Alder-type reactions

Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models.

Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit cyclooxygenase-1 (COX-1) and COX-2 enzymes. The NLRP3 inflammasome is a multi-protein complex responsible for the processing of the proinflammatory cytokine interleukin-1β and is implicated in many inflammatory diseases. Here we show that several clinically approved and widely used NSAIDs of the fenamate class are effective and selective inhibitors of the NLRP3 inflammasome via inhibition of the volume-regulated anion channel in macrophages, independently of COX enzymes. Flufenamic acid and mefenamic acid are efficacious in NLRP3-dependent rodent models of inflammation in air pouch and peritoneum. We also show therapeutic effects of fenamates using a model of amyloid beta induced memory loss and a transgenic mouse model of Alzheimer's disease. These data suggest that fenamate NSAIDs could be repurposed as NLRP3 inflammasome inhibitors and Alzheimer's disease therapeutics

Optimization of the indirect fluorimetric detection for the simultaneous analysis of inorganic anions and polycharged organic anions by capillary electrophoresis

International audienc

Utilisation des propriétés d’adsorption des tensio - actifs aux interfaces liquide / solide pour étudier certaines caractéristiques des surfaces solides.

International audienc

Surfactant mixtures at interfaces

International audienc

Simultaneous quantitative trace analysis of anionic and nonionic surfactant mixtures by reversed-phase liquid chromatography

International audienc

Polydispersity of a Non-ionic Surfactant as Related to Its Adsorption Characteristics on Porous Silica Particles in Water

International audienc

Nonideality of Mixtures of Pure Nonionic Surfactants Both in Solution and at Silica/Water Interfaces

International audienc