Inteligencia emocional percibida e implicación en diversos tipos de acoso escolar

The emotional intelligence construct has been introduced in recent years to the field of educational psychology. However, very little research has evaluated the extent to which it shapes the roles played by pupils in school contexts. Some previous studies have shown that meta-mood about one’s own emotions, perceived emotional intelligence (PEI), can distinguish students involved in bullying from those not involved. This study tries develops this area of knowledge by specifically focusing on cyberbullying situations where bullying is mediated by the use of information and communication technologies. Participants were 5759 adolescent students from Andalucia (South of Spain). The results show that PEI can discriminate between the roles young people play in traditional bullying but not for cyberbullying. These results are discussed according to possible differences in emotional management across bullying and cyberbullying

Evaluating the Effectiveness of Marketing Mix Used By Transport Network Vehicle Services

This research assessed the level of effectiveness of the 4Ps or the marketing mix employed by Grab Car using the Four Ps of Marketing—Price, Place, Promotion, and to identify if Grab Car really is living up to the expectations of the riding public in the NCR. Findings may have shown that passengers are satisfied with the services provided by Grab Car, focusing on the concerns of the commuters can still be used by Grab and other Transport Network Vehicle Services in improving their marketing strategies. Keywords: Grab Car, Marketing Mix, Marketing Strategies, Transport Network Vehicle Service

Activation of iNKT Cells Prevents Salmonella-Enterocolitis and Salmonella-Induced Reactive Arthritis by Downregulating IL-17-Producing γδT Cells

Reactive arthritis (ReA) is an inflammatory condition of the joints that arises following an infection. Salmonella enterocolitis is one of the most common infections leading to ReA. Although the pathogenesis remains unclear, it is known that IL-17 plays a pivotal role in the development of ReA. IL-17-producers cells are mainly Th17, iNKT, and γδT lymphocytes. It is known that iNKT cells regulate the development of Th17 lineage. Whether iNKT cells also regulate γδT lymphocytes differentiation is unknown. We found that iNKT cells play a protective role in ReA. BALB/c Jα18−/− mice suffered a severe Salmonella enterocolitis, a 3.5-fold increase in IL-17 expression and aggravated inflammation of the synovial membrane. On the other hand, activation of iNKT cells with α-GalCer abrogated IL-17 response to Salmonella enterocolitis and prevented intestinal and joint tissue damage. Moreover, the anti-inflammatory effect of α-GalCer was related to a drop in the proportion of IL-17-producing γδT lymphocytes (IL17-γδTcells) rather than to a decrease in Th17 cells. In summary, we here show that iNKT cells play a protective role against Salmonella-enterocolitis and Salmonella-induced ReA by downregulating IL17-γδTcells.Fil: Noto Llana, Mariangeles. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones en Microbiología y Parasitología Médica. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones en Microbiología y Parasitología Médica; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Microbiología; ArgentinaFil: Sarnacki, Sebastian Hernan. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones en Microbiología y Parasitología Médica. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones en Microbiología y Parasitología Médica; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Microbiología; ArgentinaFil: Morales, Andrea Lorena. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones en Microbiología y Parasitología Médica. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones en Microbiología y Parasitología Médica; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Microbiología; ArgentinaFil: Aya Castañeda, Maria del Rosario. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones en Microbiología y Parasitología Médica. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones en Microbiología y Parasitología Médica; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Microbiología; ArgentinaFil: Giacomodonato, Mónica Nancy. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones en Microbiología y Parasitología Médica. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones en Microbiología y Parasitología Médica; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Microbiología; ArgentinaFil: Blanco, Guillermo Armando C.. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Estudios de la Inmunidad Humoral Prof. Ricardo A. Margni. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Estudios de la Inmunidad Humoral Prof. Ricardo A. Margni; ArgentinaFil: Cerquetti, Maria Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones en Microbiología y Parasitología Médica. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones en Microbiología y Parasitología Médica; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Microbiología; Argentin

Modeling the contribution of genetic variation to cognitive gains following training with a machine learning approach

The objective of this research was to develop robust predictive models of the gains in working memory (WM) and fluid intelligence (Gf) following executive attention training in children, using genetic markers, gender, and age variables. We explore the influence of genetic variables on individual differences in susceptibility to intervention. Sixty-six children (males: 54.2%) aged 50.9-75.9 months participated in a four-weeks computerized training program. Information on genes involved in the regulation of dopamine, serotonin, norepinephrine, and acetylcholine was collected. The standardized pre- to post-training gains of two dependent measures were considered: WM Span backwards condition (WISC-III) and the IQ-f factor from the Kaufman Brief Intelligence Test (K-BIT). A machine-learning methodology was implemented utilizing multilayer perceptron artificial neural networks (ANN) with a backpropagation algorithm. Both ANN models reached high overall accuracy in their predictive classification. Variations in genes involved in dopamine and norepinephrine neurotransmission affect children's susceptibility to benefit from executive attention training, a pattern that is consistent with previous studies

Effect of Argon on the Properties of Copper Nitride Fabricated by Magnetron Sputtering for the Next Generation of Solar Absorbers

Copper nitride, a metastable semiconductor material with high stability at room temperature, is attracting considerable attention as a potential next-generation earth-abundant thin film solar absorber. Moreover, its non-toxicity makes it an interesting eco-friendly material. In this work, copper nitride films were fabricated using reactive radio frequency (RF) magnetron sputtering at room temperature, 50 W of RF power, and partial nitrogen pressures of 0.8 and 1.0 on glass and silicon substrates. The role of argon in both the microstructure and the optoelectronic properties of the films was investigated with the aim of achieving a low-cost absorber material with suitable properties to replace the conventional silicon in solar cells. The results showed a change in the preferential orientation from (100) to (111) planes when argon was introduced in the sputtering process. Additionally, no structural changes were observed in the films deposited in a pure nitrogen environment. Fourier transform infrared (FTIR) spectroscopy measurements confirmed the presence of Cu–N bonds, regardless of the gas environment used, and XPS indicated that the material was mainly N-rich. Finally, optical properties such as band gap energy and refractive index were assessed to establish the capability of this material as a solar absorber. The direct and indirect band gap energies were evaluated and found to be in the range of 1.70–1.90 eV and 1.05−1.65 eV, respectively, highlighting a slight blue shift when the films were deposited in the mixed gaseous environment as the total pressure increased

Molecular Modeling of Debromolaurinterol Isolated from Sea hare (Aplysia kurodai) Using MOPAC Software

This study aimed to obtain a molecular model of a cytotoxic compound debromolaurinterol isolated by Tsukamoto  et al. (2005) from sea hare (Aplysia kurodai) using Molecular Orbital Package (MOPAC) software.  This semi-empirical approach was done by creating a Z-matrix of the molecule which was then converted to its MOPAC input data.  Optimization of these data had provided the specific bond distance , bond angle, dihedral angle of the most stable molecular geometry.   Furthermore, calculated energies like heat of formation (-6.75618 kcal/mol),  ionization energy (8.80571 eV), electronic energy (-17,174.16327 eV) and core-core repulsion energy (14,651.44307 eV) were generated. The interatomic distances between atoms of the molecule were also provided that may greatly influence the physical and chemical properties.  Finally,  MOPAC calculations generated visual models of the most stable molecular geometry in stick, ball and stick, wireframe and space fill configuration. This study therefore provided new information which is very important for chemistry educators as well as biosynthetic chemist in designing possible chemical reactions in order to synthesize product or its derivative that are experimentally difficult to conduct. 

Características de las mordeduras de canes en pacientes atendidos en el Hospital Nacional Guillermo Almenara Irigoyen en Lima, periodo 2017-2020

The aim of the study was to describe dog bite accidents in patients treated at “Hospital Nacional Guillermo Almenara Irigoyen” in Lima during the period between 2017 and 2020. For this, information on dog bite accidents was collected from the epidemiological files of MINSA (format of 2015 and 2017) using an Excel database. The variables included were age group, sex, education level and birthplace (district) of the victim, owner of the aggressor animal; number, type, location, treatment and place of the injury, as well as the district of the accident. The information was analyzed using Stata 15.0 and summarized using descriptive statistics. From 187 epidemiological files, the highest number of reports of dog bite accidents were in male (66.8%), the age group was from 5 to 9 years (74%), occurred in Eastern Lima (46%) and reported during 2019 (79%). Attacks caused by dogs known by the victims predominated and caused severe injuries (97.9%), multiple wounds (47.1%), deep wounds (58.3%) and not infected (60.4%). Likewise, most of the cases were reported the same day of the accident (44.9%) and only required ambulatory care (60.4%).  It’s expected that these results may be useful for the surveillance, control, and prevention of dog bite accidents, and for raising awareness about this problem.El objetivo del estudio fue describir las características de los accidentes por mordedura de canes en pacientes atendidos en el Hospital Nacional Guillermo Almenara Irigoyen en Lima durante el periodo 2017-2020. Para ellos se elaboró una base de datos en Excel con toda la información recolectada de las fichas epidemiológicas elaboradas por el MINSA para accidentes por mordeduras de perros (modelos del año 2015 como del 2017) considerando como variables de estudio a: grupo etario, sexo, grado de instrucción y distrito de procedencia de la víctima, propietario del animal agresor; número, tipo, localización, tratamiento y lugar de la lesión, así como el distrito del accidente. La información se analizó con STATA 15.0 y se resumió mediante estadística descriptiva. De un total de 187 fichas epidemiológicas, la mayor proporción de reportes por accidentes de mordeduras de canes se presentaron en varones (66.8%), en el grupo etario de 5 a 9 años (74%), en Lima Este (46%), y durante el 2019 (79%). Predominaron los ataques ocasionados por canes conocidos por la víctima, de tipo grave (97.9%), con heridas múltiples (47.1%), profundas (58.3%) y no infectadas (60.4%). Asimismo, la mayoría de los casos fueron reportados el mismo día de la lesión (44.9%) y solo requirieron de atención ambulatoria (60.4%). Los resultados pueden servir de evidencia para fortalecer las actividades de vigilancia, control y  prevención de estos accidentes y dar a conocer la importancia de reportar cualquier caso de accidente por mordedura de canes

Analysis of Plant Growth-Promoting Effects of Fluorescent Pseudomonas Strains Isolated from Mentha piperita Rhizosphere and Effects of Their Volatile Organic Compounds on Essential Oil Composition

Many species or strains of the genus Pseudomonas have been characterized as plant growth promoting rhizobacteria (PGPR). We used a combination of phenotypic and genotypic techniques to analyze the community of fluorescent Pseudomonas strains in the rhizosphere of commercially grown Mentha piperita (peppermint). Biochemical techniques, Amplified rDNA Restriction Analysis (ARDRA), and 16S rRNA gene sequence analysis revealed that the majority of the isolated native fluorescent strains were P. putida. Use of two Repetitive Sequence-based PCR (rep-PCR) techniques, BOX-PCR and ERIC-PCR, allowed us to evaluate diversity among the native strains and to more effectively distinguish among them. PGPR activity was tested for the native strains and reference strain P. fluorescens WCS417r. Micropropagated M. piperita plantlets were exposed to microbial volatile organic compounds (mVOCs) emitted by the bacterial strains, and plant biomass parameters and production of essential oils (EOs) were measured. mVOCs from 11 of the native strains caused an increase in shoot fresh weight. mVOCs from three native strains (SJ04, SJ25,SJ48) induced changes in M. pierita EO composition. The mVOCs caused a reduction of metabolites in the monoterpene pathway, for example menthofuran, and an increase in menthol production. Menthol production is the primary indicator of EO quality. The mVOCs produced by native strains SJ04, SJ25,SJ48 and strain WCS417r were analyzed. The obtained mVOC chromatographic profiles were unique for each of the three native strains analyzed, containing varying hydrocarbon, aromatic, and alogenic compounds. The differential effects of the strains were most likely due to the specific mixtures of mVOCs emitted by each strain, suggesting a synergistic effect occurs among the compounds present

Herpes simplex virus triggers activation of calcium-signaling pathways

The cellular pathways required for herpes simplex virus (HSV) invasion have not been defined. To test the hypothesis that HSV entry triggers activation of Ca2+-signaling pathways, the effects on intracellular calcium concentration ([Ca2+]i) after exposure of cells to HSV were examined. Exposure to virus results in a rapid and transient increase in [Ca2+]i. Pretreatment of cells with pharmacological agents that block release of inositol 1,4,5-triphosphate (IP3)–sensitive endoplasmic reticulum stores abrogates the response. Moreover, treatment of cells with these pharmacological agents inhibits HSV infection and prevents focal adhesion kinase (FAK) phosphorylation, which occurs within 5 min after viral infection. Viruses deleted in glycoprotein L or glycoprotein D, which bind but do not penetrate, fail to induce a [Ca2+]i response or trigger FAK phosphorylation. Together, these results support a model for HSV infection that requires activation of IP3-responsive Ca2+-signaling pathways and that is associated with FAK phosphorylation. Defining the pathway of viral invasion may lead to new targets for anti-viral therapy