37,848 research outputs found
Statistical analysis driven optimized deep learning system for intrusion detection
Attackers have developed ever more sophisticated and intelligent ways to hack
information and communication technology systems. The extent of damage an
individual hacker can carry out upon infiltrating a system is well understood.
A potentially catastrophic scenario can be envisaged where a nation-state
intercepting encrypted financial data gets hacked. Thus, intelligent
cybersecurity systems have become inevitably important for improved protection
against malicious threats. However, as malware attacks continue to dramatically
increase in volume and complexity, it has become ever more challenging for
traditional analytic tools to detect and mitigate threat. Furthermore, a huge
amount of data produced by large networks has made the recognition task even
more complicated and challenging. In this work, we propose an innovative
statistical analysis driven optimized deep learning system for intrusion
detection. The proposed intrusion detection system (IDS) extracts optimized and
more correlated features using big data visualization and statistical analysis
methods (human-in-the-loop), followed by a deep autoencoder for potential
threat detection. Specifically, a pre-processing module eliminates the outliers
and converts categorical variables into one-hot-encoded vectors. The feature
extraction module discard features with null values and selects the most
significant features as input to the deep autoencoder model (trained in a
greedy-wise manner). The NSL-KDD dataset from the Canadian Institute for
Cybersecurity is used as a benchmark to evaluate the feasibility and
effectiveness of the proposed architecture. Simulation results demonstrate the
potential of our proposed system and its outperformance as compared to existing
state-of-the-art methods and recently published novel approaches. Ongoing work
includes further optimization and real-time evaluation of our proposed IDS.Comment: To appear in the 9th International Conference on Brain Inspired
Cognitive Systems (BICS 2018
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Gladstone and Scott: Family, identity, and nation
In the 175 years since his death, Walter Scott has regularly been hailed as an influence by politicians. Amongst the poet-novelist's nineteenth-century political admirers, William Ewart Gladstone was possibly the most ardent, genuine, and significant. Scott's poems and novels were amongst the earliest texts Gladstone read; he read no works (in English), except the Bible, so consistently or completely over such a length of time. They offered him a plethora of inspirations, ideas, and language, which he imbibed and appropriated into his public and private lives. His concept of self, his understanding of family, and his sense of home, were all forged and conducted within a Scottian frame of reference. Scott's life and works also crucially influenced Gladstone's political understanding of the Scottish nation and its people, and his conception of how he could best serve their political interests. This article casts new light on an important and influential relationship in Gladstone's life, establishing that it was neither the superficial and recreational association some have described, nor simply a ploy of an astute politician. The article falls into three parts. The first elucidates how Gladstone's consumption of Scott's writings was seminal in the formation of his private identity, both individual and familial. The second explains how Gladstone's readings of Scott fitted into the specific and serious character of his other reading and knowledge-gathering, and the third shows how the details of Gladstone's response to Scott related to the broader intellectual and cultural context of his public life. By placing Gladstone within his Scottish context, this article shows how frequently and significantly his private and public worlds intersected
Validation of the Breast Cancer Screening Beliefs Questionnaire among African Australian women
Background The Breast Cancer Screening Beliefs Questionnaire (BCSBQ) has been designed as a culturally appropriate instrument for assessing women’s beliefs, knowledge and attitudes to breast cancer and breast cancer screening practices. While it has proved to be a reliable instrument when applied to women of Chinese, Arabic and Korean origin living in Australia, its psychometric properties among women from African backgrounds have not been tested. The aim of this study is to examine the psychometric properties of the BCSBQ among African Australian women. Methods The BCSBQ was administered to 284 African Australian women who were recruited from a number of African community organizations and churches. Factor analysis was conducted to study the factor structure. Construct validity was examined using Cuzick’s non-parametric test while Cronbach alpha was used to assess internal consistency reliability. Results Exploratory factor analysis results demonstrated that the African-Australian BCSBQ can be conceptualized as a 4-factor model. The third factor, viz. “barriers to mammography”, was split into two separate factors namely, “psychological” and “practical” barriers. The results indicated that the African-Australian BCSBQ had both satisfactory validity and internal consistency. The Cronbach’s alpha of the three subscales ranged between 0.84-0.92. The frequency of breast cancer screening practices (breast awareness, clinical breast-examination and mammography) were significantly associated with attitudes towards general health check-ups and perceived barriers to mammographic screening. Conclusions Our study provided evidence to support the psychometric properties of the BCSBQ.in African Australian women. The study moreover demonstrated that the use of the instrument can help health professionals to understand the beliefs, knowledge and attitudes to breast cancer among African Australian women and also the factors that impact on their breast cancer screening practices.published_or_final_versio
Breast cancer screening practices of African migrant women in Australia: a descriptive cross-sectional study
Background: Breast cancer is the most diagnosed cancer among women and a leading cause of mortality and morbidity, globally. Breast cancer mortality can be improved through routine cancer screening, yet migrant populations have lower participation rates. While African migrants are among the fastest growing migrant population in Australia, their breast cancer screening behaviour is under-studied. The aims of this study were to report breast cancer screening status of African migrant women and factors associated with their breast cancer screening behaviour in Australia. Methods: A descriptive, cross-sectional approach was utilised for this study. Two hundred and sixty four African migrant women aged 18–69 years and recruited from a number of organisations responded to a self-reported African version of the Breast Cancer Screening Beliefs Questionnaire (BCSBQ). Main research variables are breast cancer screening practices and demographic characteristics and total scores on each of the BCSBQ subscales. Multivariable logistic regression analyses were performed to investigate the impact of the demographic variables on the likelihood of women in the target age range 50–74 years having screening practices as recommended. Results: While most of the participants heard of breast awareness (76.1%) and mammogram (85.2%), only 11.4% practised monthly breast awareness, whereas 65.9% had ever had a mammogram as frequently as recommended. Age and employment were determining factors for participating in mammogram. Significant different scores were found in the “Practical barriers” between women at the target age who had and had not performed breast awareness (80.4 versus 77.5, p-value = 0.002) and mammogram (77.1 versus 70.3, p-value = 0.009) regularly as recommended. Moreover, attitudes towards general health check-ups subscale scores were significantly higher in women who had performed clinical breast examination as frequently as recommended than those who had not. Conclusions: The research reveals that practical barriers and attitudes towards general health check-ups are important factors to take into account in determining African migrant women’s participation in breast cancer screening. Progress in reducing breast cancer deaths through early detection needs to focus on attitudinal change among African migrants.published_or_final_versio
Recognizing the Valentinians--now and then
Peer reviewe
Elevated expression of artemis in human fibroblast cells is associated with cellular radiosensitivity and increased apoptosis
Copyright @ 2012 Nature Publishing GroupThis article has been made available through the Brunel Open Access Publishing Fund.Background: The objective of this study was to determine the molecular mechanism(s) responsible for cellular radiosensitivity in two human fibroblast cell lines 84BR and 175BR derived from two cancer patients. Methods: Clonogenic assays were performed following exposure to increasing doses of gamma radiation to confirm radiosensitivity. γ-H2AX foci assays were used to determine the efficiency of DNA double strand break (DSB) repair in cells. Quantitative-PCR (Q-PCR) established the expression levels of key DNA DSB repair proteins. Imaging flow cytometry using Annexin V-FITC was used to compare artemis expression and apoptosis in cells. Results: Clonogenic cellular hypersensitivity in the 84BR and 175BR cell lines was associated with a defect in DNA DSB repair measured by the γ-H2AX foci assay. Q-PCR analysis and imaging flow cytometry revealed a two-fold overexpression of the artemis DNA repair gene which was associated with an increased level of apoptosis in the cells before and after radiation exposure. Over-expression of normal artemis protein in a normal immortalised fibroblast cell line NB1-Tert resulted in increased radiosensitivity and apoptosis. Conclusion: We conclude elevated expression of artemis is associated with higher levels of DNA DSB, radiosensitivity and elevated apoptosis in two radio-hypersensitive cell lines. These data reveal a potentially novel mechanism responsible for radiosensitivity and show that increased artemis expression in cells can result in either radiation resistance or enhanced sensitivity.This work was supported in part by The Vidal Sassoon Foundation USA. This article is made available through the Brunel Open Access Publishing Fund
Stratigraphic results of diamond drilling of the Hunterston Dome, Tasmania: implications for palaeogeography and hydrocarbon potential
The structure known as the Hunterston Dome, in central Tasmania, was drilled to a depth of 1324 m, through Jurassic dolerite, Lower Parmeener Supergroup and into Precambrian dolomite basement. The base of the Lower Parmeener Supergroup does not outcrop in the area, and drilling revealed the absence of the extensive glacial diamictites present elsewhere in the Tasmania Basin. A conglomeratic facies is found in place of the Bundella Mudstone and Woody Island Siltstone. Basement to the Lower Parmeener Supergroup is shown to be deformed Precambrian dolomite, of similar lithology to the relatively undeformed Black River Dolomite of northwestern Tasmania.
Significant hydrocarbons were not encountered during drilling, but stratigraphic drilling proved the maturity of potential source beds in the region and the nature of potential reservoir rocks, where they are found in close association with a dolerite intrusion
Interpersonal interactions and empathy modulate perception of threat and defensive responses
The defensive peripersonal space (DPPS) is a vital "safety margin" surrounding the body. When a threatening stimulus is delivered inside the DPPS, subcortical defensive responses like the hand-blink reflex (HBR) are adjusted depending on the perceived threat content. In three experiments, we explored whether and how defensive responses are affected by the interpersonal interaction within the DPPS of the face. In Experiment 1, we found that the HBR is enhanced when the threat is brought close to the face not only by one's own stimulated hand, but also by another person's hand, although to a significantly lesser extent. In Experiments 2 and 3, we found that the HBR is also enhanced when the hand of the participant enters the DPPS of another individual, either in egocentric or in allocentric perspective. This enhancement is larger in participants with strong empathic tendency when the other individual is in a third person perspective. These results indicate that interpersonal interactions shape perception of threat and defensive responses. These effects are particularly evident in individuals with greater tendency to having empathic concern to other people
Low-frequency noise in GaN thin films deposited by rf-plasma assisted molecular-beam epitaxy
Author name used in this publication: W. K. Fong2001-2002 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe
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