1,747 research outputs found
Getting Your Message Across: Mobile Phone Text Messaging
Want to send a message that 99% of your audience will read? Many Extension professionals are familiar with using social media tools to enhance Extension programming. Extension professionals may be less familiar with the use of mobile phone text-based marketing tools. The purpose of this article is to introduce SMS (short message system) marketing and provide a starting point for using mass text messages in Extension programming
Portable vibration exciter
Gas-driven vibration exciter produces a sinusoidal excitation function controllable in frequency and in amplitude. It allows direct vibration testing of components under normal loads, removing the possibility of component damage due to high static pressure
Glucocorticoid with cyclophosphamide for paraquat-induced lung fibrosis.
Paraquat is an effective and widely used herbicide but is also a lethal poison. In many developing countries paraquat is widely available and inexpensive, making poisoning prevention difficult. However most of the people who become poisoned from paraquat have taken it as a means of suicide.Standard treatment for paraquat poisoning both prevents further absorption and reduces the load of paraquat in the blood through haemoperfusion or haemodialysis. The effectiveness of standard treatments is extremely limited.The immune system plays an important role in exacerbating paraquat-induced lung fibrosis. Immunosuppressive treatment using glucocorticoid and cyclophosphamide in combination is being developed and studied.
To assess the effects of glucocorticoid with cyclophosphamide on mortality in patients with paraquat-induced lung fibrosis.
The most recent search was run on the 15th April 2014. We searched the Cochrane Injuries Group's Specialised Register, The Cochrane Library, Ovid MEDLINE(R), Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations, Ovid MEDLINE(R) Daily and Ovid OLDMEDLINE(R), Embase Classic+Embase (Ovid), ISI WOS (SCI-EXPANDED, SSCI, CPCI-S & CPSI-SSH), trials registries, Chinese databases (, , ) and reference lists.
RCTs were included in this review. All patients were to receive standard care, plus the intervention or control. The intervention was glucocorticoid with cyclophosphamide in combination versus a control of a placebo, standard care alone or any other therapy in addition to standard care.
The mortality risk ratio (RR) and 95% confidence interval (CI) was calculated for each study on an intention-to-treat basis. Data for all-cause mortality at final follow-up were summarised in a meta-analysis using a fixed-effect model.
This systematic review includes three trials with a combined total of 164 participants who had moderate to severe paraquat poisoning. Patients who received glucocorticoid with cyclophosphamide in addition to standard care had a lower risk of death at final follow-up than those receiving standard care only (RR 0.72; 95% CI 0.59 to 0.89).
Based on the findings of three small RCTs of moderate to severely poisoned patients, glucocorticoid with cyclophosphamide in addition to standard care may be a beneficial treatment for patients with paraquat-induced lung fibrosis. To enable further study of the effects of glucocorticoid with cyclophosphamide for patients with moderate to severe paraquat poisoning, hospitals may provide this treatment as part of an RCT with allocation concealment
Evanescent-wave coupled right angled buried waveguide: Applications in carbon nanotube mode-locking
In this paper we present a simple but powerful subgraph sampling primitive
that is applicable in a variety of computational models including dynamic graph
streams (where the input graph is defined by a sequence of edge/hyperedge
insertions and deletions) and distributed systems such as MapReduce. In the
case of dynamic graph streams, we use this primitive to prove the following
results:
-- Matching: First, there exists an space algorithm that
returns an exact maximum matching on the assumption the cardinality is at most
. The best previous algorithm used space where is the
number of vertices in the graph and we prove our result is optimal up to
logarithmic factors. Our algorithm has update time. Second,
there exists an space algorithm that returns an
-approximation for matchings of arbitrary size. (Assadi et al. (2015)
showed that this was optimal and independently and concurrently established the
same upper bound.) We generalize both results for weighted matching. Third,
there exists an space algorithm that returns a constant
approximation in graphs with bounded arboricity.
-- Vertex Cover and Hitting Set: There exists an space
algorithm that solves the minimum hitting set problem where is the
cardinality of the input sets and is an upper bound on the size of the
minimum hitting set. We prove this is optimal up to logarithmic factors. Our
algorithm has update time. The case corresponds to minimum
vertex cover.
Finally, we consider a larger family of parameterized problems (including
-matching, disjoint paths, vertex coloring among others) for which our
subgraph sampling primitive yields fast, small-space dynamic graph stream
algorithms. We then show lower bounds for natural problems outside this family
Thermal conductivity of zirconia thermal barrier coatings
Thermal barrier coatings (TBC's) applied to the hot gas components of turbine engines lead to enhanced fuel efficiency and component reliability. Understanding the mechanisms which control the thermal transport behavior of the TBC's is of primary importance. Physical vapor description (PVD) and plasma spraying (PS) are the two most commonly used coating techniques. These techniques produce coatings with unique microstructures which control their performance and stability. The PS coatings were applied with either standard power or hollow sphere particles. The hollow sphere particles yielded a lower density and lower thermal conductivity coating. The thermal conductivity of both fully and partially stabilized zirconia, before and after thermal aging, will be compared. The thermal conductivity of the coatings permanently increase upon being exposed to high temperatures. These increases are attributed to microstructural changes within the coatings. Sintering of the as fabricated plasma sprayed lamellar structure is observed by scanning electron microscopy of coatings isothermally heat treated at temperatures greater than 1100 C. During this sintering process the planar porosity between lamella is converted to a series of small spherical pores. The change in pore morphology is the primary reason for the observed increase in thermal conductivity. This increase in thermal conductivity can be modeled using a relationship which depends on both the temperature and time of exposure. Although the PVD coatings are less susceptible to thermal aging effects, preliminary results suggest that they have a higher thermal conductivity than PS coatings, both before and after thermal aging. The increases in thermal conductivity due to thermal aging for partially stabilized plasma sprayed zirconia have been found to be less than for fully stabilized plasma sprayed zirconia coatings. The high temperature thermal diffusivity data indicates that if these coatings reach a temperature above 1100 C during operation, they will begin to lose their effectiveness as a thermal barrier
Recommended from our members
HUMAN LUNG CANCER RISKS FROM RADON – PART III - EVIDENCE OF INFLUENCE OF COMBINED BYSTANDER AND ADAPTIVE RESPONSE EFFECTS ON RADON CASE-CONTROL STUDIES - A MICRODOSE ANALYSIS
Since the publication of the BEIR VI (1999) report on health risks from radon, a sig- nificant amount of new data has been published showing various mechanisms that may affect the ultimate assessment of radon as a carcinogen, in particular the potentially deleterious Bystander Effect (BE) and the potentially beneficial Adaptive Response radio-protection (AR). The case-control radon lung cancer risk data of the pooled 13 European countries radon study (Darby et al 2005, 2006) and the 8 North American pooled study (Krewski et al 2005, 2006) have been evaluated. The large variation in the odds ratios of lung cancer from radon risk is reconciled, based on the large variation in geological and ecological conditions and variation in the degree of adaptive response radio-protection against the bystander effect induced lung damage. The analysis clearly shows Bystander Effect radon lung cancer induction and Adaptive Response reduction in lung cancer in some geographical regions. It is estimated that for radon levels up to about 400 Bq m-3 there is about a 30% probability that no human lung cancer risk from radon will be experienced and a 20% probability that the risk is below the zero-radon, endogenic spontaneous or perhaps even genetically inheritable lung cancer risk rate. The BEIR VI (1999) and EPA (2003) estimates of human lung cancer deaths from radon are most likely significantly excessive. The assumption of linearity of risk, by the Linear No-Threshold Model, with increasing radon exposure is invalid
Labour self-sufficiency on family dairy farms in Ireland: a case study approach considering labour requirement, input and management
The efficient use of labour input is essential to the success of farms; however, many countries are experiencing a decreasing family workforce on-farm as a result of perceived labour intensive work and poor work–life balance. Four farms identified from two labour time-use studies were selected as case studies to investigate management of the family dairy farm in terms of herd size, while also meeting the labour requirements and maintaining a satisfactory work–life balance. A mixed methods approach was used; quantitative analysis described the labour profile and characteristics of the farms, while the qualitative interviews provided insights into strategies to achieve labour efficiency. The results demonstrate that a family farm with a herd size of ∼120 cows with appropriate facilities and streamlined practices can operate effectively with a total labour input of 2,986 h/yr. The labour contributed by the farmer and the farm family represented 77.5% of the total annual labour requirement. Contractors or hired employees contributed the remaining labour input, depending on individual circumstances. The annual average working day length for the farmer (excluding breaks) was 7.8 h/d. The analysed narratives of the farmers demonstrated their view that a seasonal, pasture-based spring calving system of production is a key influence in achieving relatively high labour efficiency on-farm, if it is ensured that the peak workload in spring is managed effectively. The study highlights that the overall labour demand can be reduced on Irish family farms through the management of facilities and practices. The farmer and family members can then decide on the degree of self-sufficiency with regard to labour, that is, what proportion of that labour they wish to contribute based on their lifestyle choices, cost and availability of contractors and hired workers
Exact Bayesian curve fitting and signal segmentation.
We consider regression models where the underlying functional relationship between the response and the explanatory variable is modeled as independent linear regressions on disjoint segments. We present an algorithm for perfect simulation from the posterior distribution of such a model, even allowing for an unknown number of segments and an unknown model order for the linear regressions within each segment. The algorithm is simple, can scale well to large data sets, and avoids the problem of diagnosing convergence that is present with Monte Carlo Markov Chain (MCMC) approaches to this problem. We demonstrate our algorithm on standard denoising problems, on a piecewise constant AR model, and on a speech segmentation problem
An evaluation of Cochrane Crowd found that crowdsourcing produced accurate results in identifying randomised trials
BACKGROUND: Filtering the deluge of new research to facilitate evidence synthesis has proven to be unmanageable using current paradigms of search and retrieval. Crowdsourcing, a way of harnessing the collective effort of a 'crowd' of people, has the potential to support evidence synthesis by addressing this information overload created by the exponential growth in primary research outputs. Cochrane Crowd, Cochrane's citizen science platform, offers a range of tasks aimed at identifying studies related to healthcare. Accompanying each task are brief, interactive training modules and agreement algorithms that help ensure accurate collective decision-making. OUR OBJECTIVES WERE: (1) to evaluate the performance of Cochrane Crowd in terms of its accuracy, capacity and autonomy; and (2) to examine contributor engagement across three tasks aimed at identifying randomised trials. STUDY DESIGN: Crowd accuracy was evaluated by measuring the sensitivity and specificity of crowd screening decisions on a sample of titles and abstracts, compared with 'quasi gold-standard' decisions about the same records using the conventional methods of dual screening. Crowd capacity, in the form of output volume, was evaluated by measuring the number of records processed by the crowd, compared with baseline. Crowd autonomy, the capability of the crowd to produce accurate collectively-derived decisions without the need for expert resolution, was measured by the proportion of records that needed resolving by an expert. RESULTS: The Cochrane Crowd community currently has 18,897 contributors from 163 countries. Collectively, the Crowd has processed 1,021,227 records, helping to identify 178,437 reports of randomised trials (RCTs) for Cochrane's Central Register of Controlled Trials. The sensitivity for each task was 99.1% for the randomised controlled trial identification task (RCT ID), 99.7% for the randomised controlled trial identification task of trial from ClinicalTrials.gov (CT ID) and 97.7% for identification of randomised controlled trials from the International Clinical Trials Registry Platform (ICTRP ID). The specificity for each task was 99% for RCT ID, 98.6% for CT ID and 99.1% for ICTRP ID. The capacity of the combined Crowd and machine learning workflow has increased five-fold in six years, compared with baseline. The proportion of records requiring expert resolution across the tasks ranged from 16.6% to 19.7%. CONCLUSION: Cochrane Crowd is sufficiently accurate and scalable to keep pace with the current rate of publication (and registration) of new primary studies. It has also proved to be a popular, efficient and accurate way for a large number of people to play an important voluntary role in health evidence production. Cochrane Crowd is now an established part of Cochrane's effort to manage the deluge of primary research being produced
- …