Confirmations That Were Not Meant to Be: Religion, Violence and the Female Body in Un poison violent (2010), Corpo celeste (2011), and Kreuzweg (2014)

This article considers the representation of the adolescent female body and the relevance of corporeality in Catholicism in three Western European films, which have at their centre the religious confirmation. These are: Un poison violent (Love Like Poison, 2010, Katell Quilléveré), Corpo celeste (Heavenly Body, 2011, Alice Rohrwacher), and Kreuzweg (Stations of the Cross, 2014, Dietrich Brüggemann). The sacrament of confirmation as portrayed in the three films becomes the axis around which the dynamics of adolescence (i.e., changing body, blossoming sexuality, family conflicts) unfold, opening up a space for the analysis of the interplay between female subjectivities and Catholicism’s regulatory role. We look at the often-subtle violence exerted by Catholicism in an attempt to tame the female body and the ways female adolescents (re)negotiate their identity against the backdrop of religious authority. Our contention is that, in the films, the female protagonists’ subtraction from the confirmation becomes a way to distance themselves from the Catholic obedient body and reaffirm their individual, embodied subjectivity. To this end, we engage with the complex relationship between Catholicism, women, and women’s bodies, exploring the dichotomy between the Catholic ideal, unchangeable body and the continually-changing, desiring female bodies

Adherence to Psychotherapy for Post-Traumatic Stress in Veterans of Military Combat in Afghanistan (Operation Enduring Freedom) and Iraq (Operation Iraqi Freedom)

Elucidating factors associated with adherence to treatment for physical and mental health conditions is important, given well-documented associations between non-adherence and poor treatment outcomes. Researchers have worked to identify such factors; however, most studies focus on adherence to medical, rather than, psychological treatments. Clarifying variables that predict adherence to psychotherapy is particularly important for individuals with post-traumatic stress disorder (PTSD), for whom treatment, which typically involves exposure to trauma-related stimuli and imagery, can be aversive. It may consequently be associated with high nonadherence rates, even though studies indicate that greater adherence to PTSD treatment relates to better treatment outcomes. Research needs to identify factors that increase or decrease the likelihood that affected individuals will enter and complete therapy. Although several studies to date have examined adherence to treatment for PTSD, this literature is limited on several fronts. First, studies on psychotherapy adherence have identified few consistent predictors of treatment adherence. Second, adherence to psychotherapy is rarely a central focus of treatment-related research; more typically, researchers treat adherence as secondary in importance to treatment outcomes. Third, little research on psychotherapy adherence has been theoretically driven. Fourth, little adherence research has focused on combat veterans with PTSD, who tend to have particularly poor treatment outcomes. Especially lacking is knowledge about predictors of adherence in veterans who have recently returned from combat; most research focuses on veterans of the Vietnam War, many of whom were initially traumatized decades earlier. The study tested the hypothesis that elevated reports of a specific type of PTSD symptom--avoidance/emotional numbing-- predicted poorer adherence to treatment in 160 veterans who received psychotherapy. No significant associations between avoidance and emotional numbing symptoms and adherence were found. However, emotional numbing was negatively related to psychotherapy adherence. Other variables typically related to PTSD and treatment outcomes were found to be important predictors of psychotherapy adherence and completion/noncompletion of therapy

Non-Traditional Exports, Traditional Constraints: The Adoption and Diffusion of Cash Crops among Smallholders in Guatemala

More than two decades after non-traditional export crops (NTXs) were introduced to the central highlands of Guatemala to link farmers to global markets and foster rural development, this study uses duration analysis to explore how time-varying household characteristics and external trends play into both the adoption and diffusion processes of NTX among smallholders. Adoption was widespread and rapid, which led the project to be hailed as a pro-poor success, reaching all but the smallest landholders. Potential benefits of NTXs have proven to be high, but constraints to sustained adoption also numerous, particularly in the second decade of the period considered. Over time, more than two-thirds of adopters eventually dropped out, reverting back to more traditional crops, or leaving agriculture altogether. Based on a second round of a 20-year panel survey carried out by the authors, the analysis suggests that smallholders are quite responsive to price incentives when making their repeated decision to continue adopting overtime. Also, in line with previous findings, land size does not seem important in the decision to adopt. However, land quality emerges as a significant factor in prolonging NTX production over time. Overall, the findings suggest that, in the long-run, NTX production does not appear to have been as pro-poor as initially hoped, and that institutions and policy interventions were able to only partially offset these difficulties in favor of less endowed farmers.Crop Production/Industries, International Relations/Trade,

Intensified Nd extraction in small channels for NdFeB magnet recycling

Neodymium (Nd) was continuously extracted from aqueous solutions by trioctylphosphine oxide (TOPO) dissolved in the ionic liquid 1-Butyl-3-methylimidazolium Bis (trifluoromethanesulfonyl)imide ([C4mim][Tf2N]) in small channel contactors. Kinetic studies confirmed a 1:6 Nd:TOPO extraction mechanism at high initial Nd concentrations of 0.005 and 0.01 M in a 0.001 M nitric acid aqueous phase. The continuous flow extractions were carried out in channels with 0.5 and 1 mm diameter and the effects of mixture velocity and residence time on the extraction efficiency and the mass transfer coefficient were investigated. At equal phase mixture velocities, the flow pattern studies highlighted a plug flow regime at mixture velocities of 0.01 to 0.05 m/s for both channels, resulting in interfacial areas of up to 4900 m2/m3 in the 0.5 mm channel and 2500 m2/m3 in the 1 mm channel. After 37.5 s residence time, extraction efficiencies of 80 % were found in the 0.5 mm channel at a KLα of 0.09 s−1 and 70 % at 0.04 s−1 in the 1 mm channel. The same extraction efficiencies were achieved in 1–2 h in the batch systems

Combinatorial approaches to Hopf bifurcations in systems of interacting elements

We describe combinatorial approaches to the question of whether families of real matrices admit pairs of nonreal eigenvalues passing through the imaginary axis. When the matrices arise as Jacobian matrices in the study of dynamical systems, these conditions provide necessary conditions for Hopf bifurcations to occur in parameterised families of such systems. The techniques depend on the spectral properties of additive compound matrices: in particular, we associate with a product of matrices a signed, labelled digraph termed a DSR^[2] graph, which encodes information about the second additive compound of this product. A condition on the cycle structure of this digraph is shown to rule out the possibility of nonreal eigenvalues with positive real part. The techniques developed are applied to systems of interacting elements termed “interaction networks”, of which networks of chemical reactions are a special case

Excitation energies of retinal chromophores: Critical role of the structural model

We employ a variety of highly-correlated approaches including quantum Monte Carlo (QMC) and the n-electron valence state perturbation theory (NEVPT2) to compute the vertical excitation energies of retinal protonated Schiff base (RPSB) models in the gas phase. We find that the NEVPT2 excitation energies are in good agreement with the QMC values and confirm our previous findings that the complete-active-space perturbation (CASPT2) approach yields accurate excitations for RPSB models only when the more recent zero-order IPEA Hamiltonian is employed. The excitations computed with the original zero-order formulation of CASPT2 are instead systematically red-shifted by more than 0.3 eV. We then focus on the full 11-cis retinal chromophore and show that the M06-2X and MP2 approaches provide reliable ground-state equilibrium structures for this system while the complete-active-space self-consistent field (CASSCF) geometry is characterized by significantly higher ground-state energies at the NEVPT2 and CASPT2 level. Our calibration of the structural model together with the general agreement of all highly-correlated excited-state methods allows us to reliably assign a value of about 2.3 eV to the vertical excitation of 11-cis RPSB in the gas-phase

Design, synthesis and biological activity of selective hCAs inhibitors based on 2-(benzylsulfinyl)benzoic acid scaffold

A large library of derivatives based on the scaffold of 2-(benzylsulfinyl)benzoic acid were synthesised and tested as atypical inhibitors against four different isoforms of human carbonic anhydrase (hCA I, II, IX and XII, EC 4.2.1.1). The exploration of the chemical space around the main functional groups led to the discovery of selective hCA IX inhibitors in the micromolar/nanomolar range, thus establishing robust structure-activity relationships within this versatile scaffold. HPLC separation of some selected chiral compounds and biological evaluation of the corresponding enantiomers was performed along with molecular modelling studies on the most active derivatives

Preferential expression of the transcription coactivator HTIF1alpha gene in acute myeloid leukemia and MDS-related AML

HTIF1α, a transcription coactivator which is able to mediate RARα activity and functionally interact with PML, is encoded by a gene on chromosome 7q32–34, which is a critical region in acute myeloid leukemias (AML). With the assumption that this gene may be related to AML, we investigated the HTIF1α DNA structure and RNA expression in leukemic cells from 36 M1–M5 AML patients (28 ‘de novo’ and eight ‘secondary’ to myelodysplastic syndrome (MDS)). Abnormal HTIF1α DNA fragments were never found, whereas loss of HTIF1α DNA was observed in the patients with chromosome 7q32 deletion and translocation, and in one case without detectable chromosome 7 abnormality. HTIF1α RNA was found in acute myelocytic leukemic blasts, and was almost undetectable in normal mononuclear cells. The expression varied among the patients: higher in M1 to M3 subtypes, with the highest values in M1; low levels were constantly observed in M4 and M5 AML. In addition, HTIF1α was significantly overexpressed in MDS-related AML (MDR-AML), but not in MDS. We also found that HTIF1α expression was high in myeloid cell lines. In myeloblastic HL60 and promyelocytic NB4 cells, induced to differentiate along the monocytic–macrophage pathway by TPA or vitamin D3, HTIF1α expression decreased, whereas it was maintained at high levels on induction to granulocytic differentiation by RA or DMSO. In K562 cells, HTIF1α RNA levels did not change after hemin-induced erythroid differentiation. These results suggest that HTIF1α could play a role in myeloid differentiation, being distinctly regulated in hematopoietic lineages

Taking on different roles: how educators position themselves in MOOCs

Educators in massive open online courses (MOOCs) face the challenge of interacting with tens of thousands of students, many of whom are new to online learning. This study investigates the different ways in which lead educators position themselves within MOOCs, and the various roles that they adopt in their messages to learners. Email messages from educators were collected from six courses on FutureLearn, a UK-based MOOC platform that had 26 university partners at the time. Educator stance in these emails was coded thematically, sentence by sentence. The resulting typology draws attention to the different ways in which educators align themselves in these settings, including outlining the trajectory of the course, acting as both host and instructor, sometimes as fellow learner, and often as an emotionally engaged enthusiast. This typology can be used to explore relationships between educator stance and variables such as learner engagement, learner test results and learner retention