150 research outputs found

    On Generalized Self-Duality Equations Towards Supersymmetric Quantum Field Theories Of Forms

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    We classify possible `self-duality' equations for p-form gauge fields in space-time dimension up to D=16, generalizing the pioneering work of Corrigan et al. (1982) on Yang-Mills fields (p=1) for D from 5 to 8. We impose two crucial requirements. First, there should exist a 2(p+1)-form T invariant under a sub-group H of SO(D). Second, the representation for the SO(D) curvature of the gauge field must decompose under H in a relevant way. When these criteria are fulfilled, the `self-duality' equations can be candidates as gauge functions for SO(D)-covariant and H-invariant topological quantum field theories. Intriguing possibilities occur for dimensions greater than 9, for various p-form gauge fields.Comment: 20 pages, Late

    Remarks on Covariant Matrix Strings

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    We address the issue of the worldsheet and spacetime covariant formulation for matrix strings. The problem is solved in the limit of vanishing string coupling. To go beyond the g_s = 0 limit, we propose a topological quantum field theory as a twisted candidate. Our model involves the generalized octonionic or SU(4) instanton equations defined in eight dimensions for a supersymmetric U(N) Yang--Mills field living on a special holonomy manifold. The question of untwisting this matrix model into an anomaly free theory enlightens the need for an "extended" 2d-gravity sector, that we suggest could be (partially twisted) W-gravity.Comment: 15 pages, harvmac. References added, version to appear in PL

    Release of hydro-soluble microalgal proteins using mechanical and chemical treatments

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    In order to release proteins in the aqueous phase, high-pressure homogenization and alkaline treatments were applied to rupture the cell walls of five intensively grown microalgae. Protein characterisation was carried out by analysing the amino acid profiles of both the crude microalgae and the protein extracts, obtained after both types of treatment. The results showed that the proportion of proteins released from microalgae following both treatments was, in descending order: Porphyridium cruentum>Arthrospira platensis>Chlorella vulgaris>Nannochloropsis oculata>Haematococcus pluvialis, reflecting the increasingly protective, cell walls. Nonetheless, mechanical treatment released more proteins from all the microalgae compared to chemical treatment. The highest yield was for the fragile cell walled P. cruentum with 88% hydro-soluble proteins from total proteins, and the lowest from the rigid cell walled H. pluvialis with 41%. The proportion of essential and non-essential amino acids in the extract was assessed and compared to the crude microalgae profile. It was higher after alkaline treatment and much higher after high-pressure homogenization. These results suggest that non-essential amino acids are more concentrated actually inside the cells and that different types of proteins are being released by these two treatments

    Aqueous extraction of proteins from microalgae: Effect of different cell disruption methods

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    The microalgal structure has been investigated to evaluate the release of proteins in aqueous media from five microalgae after conducting different cell disruption techniques: manual grinding, ultrasonication, alkaline treatment, and high-pressure treatment. After conducting cell disruption, the protein concentration in water was determined for all the microalgae and the results are discussed within the context of their cell wall structure. It was found that the aqueous media containing most protein concentration followed the order: high-pressure cell disruption>chemical treatment>ultrasonication>manual grinding. Fragile cell-walled microalgae were mostly attacked according to the following order: Haematococcus pluvialis<Nannochloropsis oculata<Chlorella vulgaris<Porphyridium cruentum≀Arthrospira platensis

    Understanding the effect of cell disruption methods on the diffusion of Chlorella vulgaris proteins and pigments in the aqueous phase

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    Cell disruption of microalgae is usually evaluated by microscopic observations and quantification of the target molecules before and after cell disruption. The following study considers a new approach by analysing the diffusion behaviour of proteins and pigments of Chlorella vulgaris in an aqueous medium after applying different cell disruption methods. Results were revealed by microscopic observations, quantifying the concentration of the molecules of interest, and calculating their diffusion coefficient. Microscopic observations showed intact cells after applying chemical hydrolysis and ultrasonication. However, the majority of the cells lost their globular shape after bead milling and high-pressure homogenization. The protein concentration increased in the following order: ultrasonication bead milling > ultrasonication > high-pressure homogenization. Pigments were not detected in the aqueous phase of the chemical hydrolysis treatment, but their concentration and their diffusion were in the same order as proteins in the mechanical treatments. The study implied that diffusivity of the target molecules was not directly correlated to their increase concentration in the aqueous phase. Therefore, even if the cells were completely broken, diffusivity followed the hindered molecule diffusion phenomenon, which implies that somehow cells are not completely disrupted

    Development and validation of a questionnaire assessing volitional competencies to enhance the performance of physical activities in chronic low back pain patients

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    BACKGROUND: Motivation has long been emphasized as the most important determinant of action. However, there is a substantial gap between people's goals and their attainment. Patients may be motivated and yet unable to take action if their volitional competencies are insufficient. One of the important tasks of volition is goal-maintenance. Research has stressed the importance of a volitional tool, the implementation intentions. Implementation intentions indicate where, when, and how the action leading to the goal will be performed. Forming implementation intentions favours the execution of goal-directed efforts, and reinforces the relationship between intentions and behaviours. Results from various studies clearly suggest that volitional competencies and implementation intentions could play a role in low back pain (LBP) patients. However, there is at present no questionnaire allowing assessing the capacity of implementation intentions of physical activities in LBP patients. METHODS/DESIGN: This study will develop such a questionnaire, using a 3-step approach. A first qualitative step to build categories and generate items; 30 patients suffering chronic LBP will be invited to participate in semi-structured interviews; verbatim and derived items will then be submitted to a panel of experts, using a Delphi method; a second quantitative step to examine the properties of items, and determine the factorial structure of the questionnaire; 100 patients suffering chronic LBP will be recruited to respond to this phase; and third, preliminary psychometric analyses (item-scale correlations, construct validity, reliability); 180 chronic LBP patients will be recruited for this phase of the study. The relationships between implementation intentions and variables affecting physical activity on chronic LBP patients, i.e. pain, physical capacities, fear-avoidance beliefs, kinesiophobia, work status, and level of physical activity will be considered. DISCUSSION: Developing a questionnaire to assess implementation intentions would allow investigating the role of these intentions in the transition from acute to chronic LBP. The results of this study should contribute to the understanding of the psychological processes at stake in the development of chronic LBP, and in particular to the identification of factors eventually favouring patients' participation in and adherence to active physical treatments

    Exopolysaccharides from Microalgae and Cyanobacteria: Diversity of Strains, Production Strategies, and Applications

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    International audienceMicroalgae and cyanobacteria are photosynthetic organisms that can produce/accumulate biomolecules with industrial interest. Among these molecules, EPSs are macromolecular polysaccharidic compounds that present biological activities and physico-chemical properties, allowing to consider their valorization in diverse commercial markets, such as cosmetic, therapeutic, nutraceutic, or hydrocolloids areas. The number of microalgae and cyanobacteria strains described to produce such EPSs has increased in recent years as, among the 256 producing strains gathered in this review, 86 were published in the last 10 years (~33%). Moreover, with the rise of research on microalgae EPSs, a variety of monosaccharides compositions have been discovered, highlighting the versatility of these organisms. If some production strategies can be applied to increase EPS production yields, it appears that case by case studies are needed to promote EPS synthesis by a strain, as many responses exist. This paper proposes an up-to-date state of the art of the diversity of microalgae and cyanobacteria EPS-producing strains, associated to the variability of compositions. The strategies for the production and extraction of the polymers are also discussed. Finally, an overview of the biological activities and physico-chemical properties allow one to consider their use on several commercial markets

    ACCIDENTS VASCULAIRES CEREBRAUX ISCHEMIQUES DE L'ENFANT (A PROPOS DE 8 CAS)

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    LIMOGES-BU MĂ©decine pharmacie (870852108) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF
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