A study on the effectivness of Guggulu based Karaveera Ksharasutra in comparison with Apamarga Ksharasutra in the management of Shalyaja Nadivrana w.s.r. to Pilonidal Sinus

Shalyaja Nadivrana is of Agantuja Vranabedha. Nidana Panchaka is described in Sushruta Samhita Nidhana and Chikitsa Sthana. Presence of “Shalya” is hindering factor for healing. Management of Nadivrana includes Ksharasutra ligation. Pilonidal sinus is acquired sinus occurring in young hirsute men’s commonly seen at intergluteal cleft caused by hair penetrating the skin resulting in Pilonidal abscess which gradually forms into sinus with presence of “Hair” leading to wound discharge. It is one of the troublesome diseases which doesn’t respond to medical management till hair is evacuated. The current surgical procedures adopted have surgical risk and recurrence as well. Guggulu and Karaveera is abundantly available and can be preserved easily for long time. Hence can be used as substitute to the standard Ksharasutra. The present study “A study on the effectiveness of Guggulu based Karaveera Ksharasutra in comparison with Apamarga Ksharasutra in the management of Shalyaja Nadivrana w.s.r. to Pilonidal Sinus”was conducted in SJIIM hospital Bengaluru with 40 patients randomly allotted into 2 groups namely - Group A and Group B. Assessment was done based on subjective parameters like (pain, discharge) and objective parameters like (length of tract, tenderness). Observation was done before treatment and on every 7th day till tract is completely cut and healed. Assessment of Pain, discharge, length of tract and tenderness in Group-A showed 100%, 100%, 100% and 100% improvement and in Group-B showed 97.92%, 100%, 100% and 100% respectively. UCT in Group-A is 6.58% and Group-B is 9.15%. Overall results of group A and B is 100% and 99.5% respectively. Statistical analysis revealed that the effectiveness of Guggulu based Karaveera Ksharasutra in Shalyaja Nadivrana is as effective as Apamarga Ksharasutra w.s.r. to pilonidal sinus

Selves creating stories creating selves: A process model of self development

This article is focused on the growing empirical emphasis on connections between narrative and self-development. The authors propose a process model of self-development in which storytelling is at the heart of both stability and change in the self. Specifically, we focus on how situated stories help develop and maintain the self with reciprocal impacts on enduring aspects of self, specifically self-concept and the life story. This article emphasizes the research that has shown how autobiographical stories affect the self and provides a direction for future work to maximize the potential of narrative approaches to studying processes of self-development. Keywords: self; identity; narrative; autobiographical memory The universe is made up of stories, not of atoms. —Rukeyser (1968) This excerpt from Rukeyser’s poem suggests that, as humans, our worlds are stories; we are made up of, engage in, and are surrounded by stories. The importance of stories is a proposition that is gaining prominence in empirical psychology, and we build on this trend by proposing a process model of narrative selfdevelopment that has at its heart the study of personal autobiographical narratives, or situated stories. We use the term situated stories to emphasize the fact that any narrative account of personal memory is created within a specific situation, by particular individuals, for particular audiences, and to fulfill particular goals. These facts about situated stories provide the backdrop for our major proposition, which is that situated stories are used to develop and maintain the self. We view self-development through situated stories as a lifespan process, beginning in early childhood and extending to old age, and that process is situated in a larger cultural milieu that holds expectations of what makes a healthy narrative and a healthy self. The ideas that stories and self are intimatel

Surveillance data on micro-organisms in respiratory tract infections at a tertiary care teaching hospital in South India

Background: Respiratory tract infections are the leading cause of infections and associated hospitalizations in India. Generally, there is little control on the use of antibiotics. Community awareness of the issues involved in antibiotic therapy is poor and this is compounded by over-the-counter availability. The main aim was to compare the resistance developed by respiratory microbes.Methods: A retrospective and prospective study was designed and conducted to compare the pattern of resistance developed by microorganisms affecting the respiratory tract.Results: The sensitivity of K. pneumoniae to cefepime/tazobactum has decreased from 91.9% to 47.6% and S. aureus to Linezolid has decreased from 93.4% to 80% and S. pyogenes to azithromycin from 51.4% to 24.8%. Whereas sensitivity pattern of S. pneumoniae to amoxicillin/clavulanate is increased from 65.6% to 82.3%. The prevalence of Klebsiella pneumoniae was increased 19% to 25.2% whereas the prevalence of S. pneumoniae was decreased from 66.8% to 65.2%. Our study suggests that all microorganisms isolated are susceptible to carbapenems and cefepime/tazobactum in the cephalosporin class.Conclusions: There is major shift in the sensitivity pattern of microorganisms towards antibiotics. Therefore, these results must be kept in mind by the practitioners in the study site, prior to making decisions over a medication regimen empirically for patients and also to maximize the output of medications by rational prescribing and dosing.

Cognitive function of older adults engaging in physical activity

Background: Physical activity can be classified as open-skilled or closed-skilled. Open-skilled physical activity, such as tennis, require participants to perform within a dynamic setting and respond to unpredictable and frequent environmental changes throughout the activity. Closed-skilled types of physical activity, such as swimming, are predictable and self-directed. However, the benefits of cognitive function in these two types of physical activities to older adults are unknown. This study examined the effects of participation in open- and closed-skilled physical activity on the cognitive function of older adults. Methods: The study recruited a total of 61 participants aged 65 years and over. Participant recruitment was achieved by distributing flyers asking for volunteers in various sports venues. Participants self-reported to be without medical conditions affecting their physical and cognitive function. All participants underwent a two-hour assessment session involving the completion of seven standardised cognitive function assessments, which were used to assess a range of cognitive function. Results: Overall mean scores across all of the assessments showed superior performance for the open- or closed-skilled participants when compared with the no-physical-activity group. The results of 61 adults who participated in this study showed that closed-skilled physical activity was associated with better selective attention and visuospatial function while open-skilled physical activity was associated with better inhibition and cognitive flexibility function. No significant difference in self-regulation ability was found between the open- or closed-skilled groups. Conclusions: Open-skilled physical activity was associated with better inhibition, visual tracking, and cognitive flexibility while closed-skilled physical activity was associated with better selective attention and visuospatial perception. The findings have important practical implications for the health and quality of life of ageing populations, knowing which particular types of physical activity might affect the cognitive function

Studies on lipase enzyme production by indigenously isolated Bacillus Cereus (BAIT GCT 127002 ) and Bacillus Cereus (BAIT GCT 127001)

Microbial lipases holds a prominent place among biocatalysts that act on carboxylic ester bonds.  This present study involves about eight strains isolated form slaughter house waste water,Coimbatore producing lipase.Among those strains , two bacterial strains exhibiting high lipase production  were identified as  Bacillus Cereus (BAIT GCT 127002 ) and Bacillus Cereus (BAIT GCT 127001 ) by both biochemical analysis and 16S rRNA sequencing.  Initial studies were done for optimizing lipase production using many components such as time course,Carbon sources ,pH and innoculum volume which  revealed maximum lipase acitivity (43.37 U/ml) at 24 hours, using  palm oil , at pH 8 and innoculum volume of 1 ml by Bacillus Cereus (BAIT GCT 127002 ).Further the percentage  removal of oil from oil stained fabric was determined using partially purified lipase with or without detergents and the results indicated 20% ,30% removal with use of  crude lipase and commercial detergent respectively.Hence, lipase from Bacillus Cereus(BAIT GCT 127002 )   can be regarded as an ideal ingredient that can be used in the laundry detergents.Â&nbsp