20 research outputs found

    Rectus abdominis muscle flap (RAMF) technique for the management of large bladder defects: Urodynamic findings in a rabbit model

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    Objective To investigate the efficacy of the rectus abdominis muscle flap (RAMF) technique for the closure and augmentation of small, inelastic bladder extrophies using a rabbit model with a large bladder defect

    Rectus abdominis muscle flap (RAMF) technique for the management of bladder exstrophies: Late clinical outcome and urodynamic findings

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    Objective To investigate the efficacy of the rectus abdominis muscle nap (RAMF) technique for the closure and augmentation of small, non-compliant bladder extrophies

    MATERNAL COCAINE ABUSE RESULTING IN NECROTIZING ENTEROCOLITIS - AN EXPERIMENTAL-STUDY IN A RAT MODEL

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    The aim of this study was to assess the relation between the use of cocaine during pregnancy and development of necrotizing enterocolitis in a rat model. Different doses of cocaine HCl were given to pregnant Wistar Albino rats during gestation. Total number of live births, mean birth weight, mean placental weight and histopathological examination of the maternal uterus, placenta, embryonal G-I tract and liver were investigated. These results were compared with a control group and showed that the number of live births, mean birth weight and mean placental weight were lower than in non-cocaine controls. Histopathologic examinations revealed severe inflammation and vascular changes in the uterus and placenta. We also observed focal necrosis, necrobiosis, cellular debris, haemorrhage, inflammatory reactions in the G-I tract of embryos. These findings indicate that maternal cocaine abuse should probably be considered a major risk factor for development of NEC in baby rats and embryos

    Bladder augmentation: Urodynamic findings and clinical outcome in different augmentation techniques

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    Objective: To compare the urodynamic findings and clinical outcome in different bladder augmentation techniques

    The roles of extracellular matrix proteins, apoptosis and c-kit positive cells in the pathogenesis of ureteropelvic junction obstruction

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    Aim: To investigate histopathological changes in ureteropelvic junction obstruction (UPJO) from an etiological perspective
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