Functional Analysis of the Role of Toxin-Antitoxin (TA) Loci in Bacterial Persistence.

Bacterial Persistence: Methods and ProtocolsThe final publication is available at Springer via http://dx.doi.org/10.1007/978-1-4939-2854-5_11We have developed a method to analyze the functionality of putative TA loci by expressing them in Escherichia coli. Here, we describe the procedure for cloning recombinant TA genes into inducible plasmids and expressing these in E. coli. Following expression, toxicity, resuscitation of growth, and changes in persister cell formation are assayed. This can confirm whether predicted TA loci are active in E. coli and whether expression can affect persister cell formation

Search for New Physics with a Monojet and Missing Transverse Energy in pp Collisions at √s= 7 TeV

A study of events with missing transverse energy and an energetic jet is performed using pp collision data at a center-of-mass energy of 7 TeV. The data were collected by the CMS detector at the LHC, and correspond to an integrated luminosity of 36 pb-1. An excess of these events over standard model contributions is a signature of new physics such as large extra dimensions and unparticles. The number of observed events is in good agreement with the prediction of the standard model, and significant extension of the current limits on parameters of new physics benchmark models is achieved

Search for New Physics with a Monojet and Missing Transverse Energy in pp Collisions at √s= 7 TeV

A study of events with missing transverse energy and an energetic jet is performed using pp collision data at a center-of-mass energy of 7 TeV. The data were collected by the CMS detector at the LHC, and correspond to an integrated luminosity of 36 pb-1. An excess of these events over standard model contributions is a signature of new physics such as large extra dimensions and unparticles. The number of observed events is in good agreement with the prediction of the standard model, and significant extension of the current limits on parameters of new physics benchmark models is achieved

Measurement of the t-Channel Single Top Quark Production Cross Section in pp̅ Collisions at √s= 7 TeV

Electroweak production of the top quark is measured for the first time in pp collisions at √s= 7 TeV, using a data set collected with the CMS detector at the LHC and corresponding to an integrated luminosity of 36 pb-1. With an event selection optimized for t-channel production, two complementary analyses are performed. The first one exploits the special angular properties of the signal, together with background estimates from the data. The second approach uses a multivariate analysis technique to probe the compatibility with signal topology expected from electroweak top-quark production. The combined measurement of the cross section is 83.6±29.8 (stat + syst) ± 3.3 (lumi) pb, consistent with the standard model expectation

Measurement of the B0s Production Cross Section with B0s → J/ Decays in pp Collisions at √s = 7 TeV

The B0s differential production cross section is measured as functions of the transverse momentum and rapidity in pp collisions at √s= 7 TeV, using the B0s → J/UO decay, and compared with predictions based on perturbative QCD calculations at next-to-leading order. The data sample, collected by the CMS experiment at the LHC, corresponds to an integrated luminosity of 40 pb-1. The B0s is reconstructed from the decays J/U → µ+µ- and O→ K+K- The integrated B0s cross section times B0s→ J/UO branching fraction in the range 8BT\u3c 50 GeV/c and │yB \u3c 2.4 is measured to be 6.9 ± 0.6 ± 0.6 nb, where the first uncertainty is statistical and the second is systematic

Search for aVectorlike Quarkwith Charge 2/3 in t + Z Events from pp Collisions at √s = 7 TeV

A search for pair-produced heavy vectorlike charge-2/3 quarks, T, in pp collisions at a center-of-mass energy of 7 TeV, is performed with the CMS detector at the LHC. Events consistent with the flavorchanging- neutral-current decay of a T quark to a top quark and a Z boson are selected by requiring two leptons from the Z-boson decay, as well as an additional isolated charged lepton. In a data sample corresponding to an integrated luminosity of 1.14 fb-1, the number of observed events is found to be consistent with the standard model background prediction. Assuming a branching fraction of 100% for the decay T → tZ, a T quark with a mass less than 475 GeV/c2 is excluded at the 95% confidence level

Search for Three-Jet Resonances in pp Collisions at √s= 7 TeV

A search for three-jet hadronic resonance production in pp collisions at a center-of-mass energy of 7 TeV has been conducted by the CMS Collaboration at the LHC, using a data sample corresponding to an integrated luminosity of 35 pb-1. Events with high jet multiplicity and a large scalar sum of jet transverse momenta are analyzed using a signature-based approach. The number of expected standard model background events is found to be in good agreement with the observed events. Limits on the cross section times branching ratio are set in a model of gluino pair production with an R-parity-violating decay to three quarks, and the data rule out such particles within the mass range of 200 to 280 GeV/c2

Transverse-Momentum and Pseudorapidity Distributions of Charged Hadrons in pp Collisions at √s=7 TeV

Charged-hadron transverse-momentum and pseudorapidity distributions in proton-proton collisions at √s=7 TeV are measured with the inner tracking system of the CMS detector at the LHC. The charged-hadron yield is obtained by counting the number of reconstructed hits, hit pairs, and fully reconstructed charged-particle tracks. The combination of the three methods gives a charged-particle multiplicity per unit of pseudorapidity dNch=dη ⃒|η|\u3c0.5= 5.78 ± 0.01(stat) ± 0.23(syst) for non-single-diffractive events, higher than predicted by commonly used models. The relative increase in charged-particle multiplicity from √s=0.9 to 7 TeV is [±66.1 ± 1.0(stat) ± 4.2(syst)]%. The mean transverse momentum is measured to be 0.545 ± 0.005(stat) ± 0.015(syst) GeV/c. The results are compared with similar measurements at lower energies

Search for Supersymmetry at the LHC in Events with Jets and Missing Transverse Energy

A search for events with jets and missing transverse energy is performed in a data sample of pp collisions collected at √s = 7 TeV by the CMS experiment at the LHC. The analyzed data sample corresponds to an integrated luminosity of 1.14 fb-1. In this search, a kinematic variable αT is used as the main discriminator between events with genuine and misreconstructed missing transverse energy. No excess of events over the standard model expectation is found. Exclusion limits in the parameter space of the constrained minimal supersymmetric extension of the standard model are set. In this model, squark masses below 1.1 TeV are excluded at 95% C.L. Gluino masses below 1.1 TeV are also ruled out at 95% C.L. for values of the universal scalar mass parameter below 500 GeV

Transverse-Momentum and Pseudorapidity Distributions of Charged Hadrons in pp Collisions at √s=7 TeV

Charged-hadron transverse-momentum and pseudorapidity distributions in proton-proton collisions at √s=7 TeV are measured with the inner tracking system of the CMS detector at the LHC. The charged-hadron yield is obtained by counting the number of reconstructed hits, hit pairs, and fully reconstructed charged-particle tracks. The combination of the three methods gives a charged-particle multiplicity per unit of pseudorapidity dNch=dη ⃒|η|\u3c0.5= 5.78 ± 0.01(stat) ± 0.23(syst) for non-single-diffractive events, higher than predicted by commonly used models. The relative increase in charged-particle multiplicity from √s=0.9 to 7 TeV is [±66.1 ± 1.0(stat) ± 4.2(syst)]%. The mean transverse momentum is measured to be 0.545 ± 0.005(stat) ± 0.015(syst) GeV/c. The results are compared with similar measurements at lower energies