3,949 research outputs found
A theoretical study of the C- 4So_3/2 and 2Do_{3/2,5/2} bound states and C ground configuration: fine and hyperfine structures, isotope shifts and transition probabilities
This work is an ab initio study of the 2p3 4So_3/2, and 2Do_{3/2,5/2} states
of C- and 2p2 3P_{0,1,2}, 1D_2, and 1S_0 states of neutral carbon. We use the
multi-configuration Hartree-Fock approach, focusing on the accuracy of the wave
function itself. We obtain all C- detachment thresholds, including correlation
effects to about 0.5%. Isotope shifts and hyperfine structures are calculated.
The achieved accuracy of the latter is of the order of 0.1 MHz.
Intra-configuration transition probabilities are also estimated.Comment: 15 pages, 2 figures, 12 table
Ground-gamma band mixing and evolution of collectivity in even-even neutron-rich nuclei with 40<Z<50
We propose an extended band mixing formalism capable of describing the
ground-gamma band interaction in a wide range of collective spectra beyond the
regions of well deformed nuclei. On this basis we explain the staggering
effects observed in the gamma bands of Mo, Ru and Pd nuclei providing a
consistent interpretation of new experimental data in the neutron rich region.
As a result the systematic behavior of the odd-even staggering effect and some
general characteristics of the spectrum such as the mutual disposition of the
bands, the interaction strength and the band structures is explained as the
manifestation of respective changes in collective dynamics of the system.Comment: 17 pages, 6 figures, 4 table
Gender studies and interdisciplinarity
In this article we consider the example of gender studies as an interdisciplinary field, and argue that gender studies, and women’s studies, from which gender studies developed, has a distinctive engagement with interdisciplinarity. By thinking about the tra- jectory of women’s studies, feminist thinking and gender studies, we suggest that this has always been an interdisciplinary field of study. We trace both the shifts and continuities in thinking between different iterations of feminist thinking to consider the three core fields of: gender, sex and sexuality; intersectionality and activism; theory and methods. The article aims to open up debate over what the constructive possibilities are of a focus upon gender, and what the relationship is between theory and activism. This article is published as part of an ongoing collection dedicated to interdisciplinary research
Effects of Growth Hormone Treatment in Adults with Prader-Willi Syndrome
OBJECTIVE: Since limited data exist on adults with Prader-Willi syndrome (PWS) and growth hormone (GH) treatment, we report our experience on the effects of treatment for one year on body composition, physical activity, strength and energy expenditure, diet, general chemistry and endocrine data with quality of life measures. DESIGN: We studied 11 adults with PWS (6F:5M; average age = 32 yrs) over a 2 year period with GH treatment during the first year only. Electrolytes, IGF-I, glucose, thyroid, insulin, lipids, body composition, physical activity and strength, diet, energy expenditure and quality of life data were collected and analyzed statistically using linear modeling at baseline, at 12 months following GH therapy and at 24 months after treatment cessation for 12 months. RESULTS: Total lean muscle mass was significantly increased (p < 0.05) during GH treatment along with moderate-vigorous physical activity and plasma IGF-I and HDL levels, but returned to near baseline after treatment. Percent body fat decreased during the 12 months of GH treatment but increased after treatment. CONCLUSIONS: Previously reported beneficial effects of GH treatment in children with PWS were found in our adults regarding body composition, physical activity and plasma HDL and IGF-I levels. Several beneficial effects diminished to near baseline after cessation of GH treatment for 12 months supporting the continuation of treatment in PWS into adulthood and possibly adults not previously treated during childhood
The Limitations of Symptom-based Heart Failure Management
Heart failure (HF) has emerged as a global epidemic and it affects about 6 million adults in the US. HF medical treatment, as recommended in guidelines, significantly improves survival and quality of life; however, the mortality burden of HF remains high. For decades, treatment has been guided, mainly by symptoms, leading to undertreatment in a range of settings. Current evidence emphasises the unfavourable outcomes of HF even in early stages or in patients who achieve reverse remodeling and remission or recovery under optimised treatment. This should stimulate efforts towards a more objective, rigorous management, covering the entire spectrum of mild, moderate and severe HF
Differentially Expressed Genes in Endometrium and Corpus Luteum of Holstein Cows Selected for High and Low Fertility Are Enriched for Sequence Variants Associated with Fertility
peer-reviewedDespite the importance of fertility in humans and livestock, there has been little success dissecting the genetic basis of fertility. Our hypothesis was that genes differentially expressed in the endometrium and corpus luteum on Day 13 of the estrous cycle between cows with either good or poor genetic merit for fertility would be enriched for genetic variants associated with fertility. We combined a unique genetic model of fertility (cattle that have been selected for high and low fertility and show substantial difference in fertility) with gene expression data from these cattle and genome-wide association study (GWAS) results in ∼20 000 cattle to identify quantitative trait loci (QTL) regions and sequence variants associated with genetic variation in fertility. Two hundred and forty-five QTL regions and 17 sequence variants associated primarily with prostaglandin F2alpha, steroidogenesis, mRNA processing, energy status, and immune-related processes were identified. Ninety-three of the QTL regions were validated by two independent GWAS, with signals for fertility detected primarily on chromosomes 18, 5, 7, 8, and 29. Plausible causative mutations were identified, including one missense variant significantly associated with fertility and predicted to affect the protein function of EIF4EBP3. The results of this study enhance our understanding of 1) the contribution of the endometrium and corpus luteum transcriptome to phenotypic fertility differences and 2) the genetic architecture of fertility in dairy cattle. Including these variants in predictions of genomic breeding values may improve the rate of genetic gain for this critical trait
Local Group Dwarf Elliptical Galaxies: II. Stellar Kinematics to Large Radii in NGC 147 and NGC 185
We present kinematic and metallicity profiles for the M31 dwarf elliptical
(dE) satellite galaxies NGC 147 and NGC 185. The profiles represent the most
extensive spectroscopic radial coverage for any dE galaxy, extending to a
projected distance of eight half-light radii (8 r_eff = 14'). We achieve this
coverage via Keck/DEIMOS multislit spectroscopic observations of 520 and 442
member red giant branch stars in NGC 147 and NGC 185, respectively. In contrast
to previous studies, we find that both dEs have significant internal rotation.
We measure a maximum rotational velocity of 17+/-2 km/s for NGC 147 and 15+/-5
km/s for NGC 185. The velocity dispersions decrease gently with radius with an
average dispersion of 16+/-1 km/s for NGC 147 and 24+/-1 km/s for NGC 185. Both
dEs have internal metallicity dispersions of 0.5 dex, but show no evidence for
a radial metallicity gradient. We construct two-integral axisymmetric dynamical
models and find that the observed kinematical profiles cannot be explained
without modest amounts of non-baryonic dark matter. We measure central
mass-to-light ratios of ML_V = 4.2+/-0.6 and ML_V = 4.6+/-0.6 for NGC 147 and
NGC 185, respectively. Both dE galaxies are consistent with being primarily
flattened by their rotational motions, although some anisotropic velocity
dispersion is needed to fully explain their observed shapes. The velocity
profiles of all three Local Group dEs (NGC 147, NGC 185 and NGC 205) suggest
that rotation is more prevalent in the dE galaxy class than previously assumed,
but is often manifest only at several times the effective radius. Since all dEs
outside the Local Group have been probed to only inside the effective radius,
this opens the door for formation mechanisms in which dEs are transformed or
stripped versions of gas-rich rotating progenitor galaxies.Comment: 16 pages, 7 figures. accepted to A
Feminist geographies of digital work
Feminist thought challenges essentialist and normative categorizations of ‘work’. Therefore, feminism provides a critical lens on ‘working space’ as a theoretical and empirical focus for digital geographies. Digital technologies extend and intensify working activity, rendering the boundaries of the workplace emergent. Such emergence heightens the ambivalence of working experience: the possibilities for affirmation and/or negation through work. A digital geography is put forward through feminist theorizations of the ambivalence of intimacy. The emergent properties of working with digital technologies create space through the intimacies of postwork places where bodies and machines feel the possibilities of being ‘at’ work
Moving out of the shadows: accomplishing bisexual motherhood
Our qualitative study explored the ways in which bisexual mothers came to identify as such and how they structured their relationships and
parenting within hetero-patriarchal society. The experiences of seven self-identified White bisexual women (aged from 28 to 56-years-old) from
across England and the Republic of Ireland were investigated through semi-structured interviews. Participants’ children were aged 8 months to
28 years old at the time of their interviews. A thematic narrative analysis highlighted the following issues that participants had encountered in
constructing their self-identity: prioritizing children; connecting and disconnecting with others and finessing self-definition; questioning societal
relationship expectations. Nevertheless, participants varied considerably in how each of the themes identified were reflected in their lives, in
particular depending upon each participant’s interpretation of her local social context. Both motherhood and self-identifying as bisexual gave a
sense of meaning and purpose to participants’ life stories, although participants sometimes foregrounded their commitment to their children
even at a personal cost to their bisexual identity. Using three different theoretical perspectives from feminist theory, queer theory and life course
theory, the narratives analysed revealed ways in which bisexual motherhood not only had been influenced both intentionally and unintentionally
by heteronormative expectations but also had directly and indirectly challenged these expectations
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