79 research outputs found

    Queering Elementary Education: A Queer Curriculum for 4th Grade

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    This project explores the positioning of queer students and queer curriculum in schools with a specific focus on elementary education. Using intersectionality as a guiding framework along with queer theories, educational theories, and feminist theories, this project examines and critiques how queer subjectivities have (not) been included in schools via curriculum for elementary school children. In an effort to better understand how educators have been successfully incorporating queer topics into their classrooms, this study uses qualitative research methods, specifically semi-structured interviews with teachers in New York City. The findings from this study have been used to create a 23-lesson curriculum for 4th grade teachers that investigates bodies, puberty, sex, gender identity, and sexual orientation. Furthermore, the curriculum uses an intersectional lens to explore how various identities such as race, gender, ability, sexuality, and religion intersect to inform understandings of privilege and discrimination

    Biopsy-based calibration of T2* magnetic resonance for estimation of liver iron concentration and comparison with R2 Ferriscan.

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    BACKGROUND: There is a need to standardise non-invasive measurements of liver iron concentrations (LIC) so clear inferences can be drawn about body iron levels that are associated with hepatic and extra-hepatic complications of iron overload. Since the first demonstration of an inverse relationship between biopsy LIC and liver magnetic resonance (MR) using a proof-of-concept T2* sequence, MR technology has advanced dramatically with a shorter minimum echo-time, closer inter-echo spacing and constant repetition time. These important advances allow more accurate calculation of liver T2* especially in patients with high LIC. METHODS: Here, we used an optimised liver T2* sequence calibrated against 50 liver biopsy samples on 25 patients with transfusional haemosiderosis using ordinary least squares linear regression, and assessed the method reproducibility in 96 scans over an LIC range up to 42 mg/g dry weight (dw) using Bland-Altman plots. Using mixed model linear regression we compared the new T2*-LIC with R2-LIC (Ferriscan) on 92 scans in 54 patients with transfusional haemosiderosis and examined method agreement using Bland-Altman approach. RESULTS: Strong linear correlation between ln(T2*) and ln(LIC) led to the calibration equation LIC = 31.94(T2*)-1.014. This yielded LIC values approximately 2.2 times higher than the proof-of-concept T2* method. Comparing this new T2*-LIC with the R2-LIC (Ferriscan) technique in 92 scans, we observed a close relationship between the two methods for values up to 10 mg/g dw, however the method agreement was poor. CONCLUSIONS: New calibration of T2* against liver biopsy estimates LIC in a reproducible way, correcting the proof-of-concept calibration by 2.2 times. Due to poor agreement, both methods should be used separately to diagnose or rule out liver iron overload in patients with increased ferritin

    Automatic Coating Of Tablets.

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    PhDPharmacologyUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttp://deepblue.lib.umich.edu/bitstream/2027.42/185474/2/6203226.pd

    The granulation of binary mixtures

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