The Life and Times of Edward Fenwick Neufville

Edward Fenwick Neufville was born November 28, 1841. He was the son of Reverend Edward and Mary Neufville. Edward attended school at St. Timothy\u27s in Baltimore, Maryland and College at Princeton. He enlisted in the Confederate Army in Georgia and later was commissioned an officer in the Confederate Marines. After the war, he became an Insurance Agent, a Realtor, and also had a law practice. Edward would marry twice. His first marriage was to Mary Drayton. After her death in 1882, he married Harriet Tattnall, his late wife\u27s sister. This marriage lasted until Edward\u27s death, September 9, 1890. He was 49 years old. Harriet died December 21, 1904. Edward\u27s surviving daughter of his first Fenwick Neufville, married William B.J. Adams. They would have three children. marriage, Mary They would havehttps://digitalcommons.georgiasouthern.edu/sav-bios-lane/1171/thumbnail.jp

In situ Raman gain between hyperfine ground states in a potassium magneto-optical trap

We study optical gain in a gas of cold 39K atoms. The gain is observed during operation of a conventional magneto-optical trap without the need for additional fields. Measurements of transmission spectra from a weak probe show that the gain is due to stimulated Raman scattering between hyperfine ground states. The experimental results are reproduced by a simplified six-level model, which also helps explain why such gain is not observed in similar experiments with rubidium or cesium.Comment: 7 pages, 7 figures; submitted for publication; v2: minor changes in response to Referee comments; v3: version accepted for publication in PR

Pauci-immune glomerulonephritis in individuals with disease associated with levamisole-adulterated cocaine: a series of 4 cases.

Exposure to levamisole-adulterated cocaine can induce a distinct clinical syndrome characterized by retiform purpura and/or agranulocytosis accompanied by an unusual constellation of serologic abnormalities including antiphospholipid antibodies, lupus anticoagulants, and very high titers of antineutrophil cytoplasmic antibodies. Two recent case reports suggest that levamisole-adulterated cocaine may also lead to renal disease in the form of pauci-immune glomerulonephritis. To explore this possibility, we reviewed cases of pauci-immune glomerulonephritis between 2010 and 2012 at an inner city safety net hospital where the prevalence of levamisole in the cocaine supply is known to be high. We identified 3 female patients and 1 male patient who had biopsy-proven pauci-immune glomerulonephritis, used cocaine, and had serologic abnormalities characteristic of levamisole-induced autoimmunity. Each also had some other form of clinical disease known to be associated with levamisole, either neutropenia or cutaneous manifestations. One patient had diffuse alveolar hemorrhage. Three of the 4 patients were treated with short courses of prednisone and cyclophosphamide, 2 of whom experienced stable long-term improvement in their renal function despite ongoing cocaine use. The remaining 2 patients developed end-stage renal disease and became dialysis-dependent. This report supports emerging concern of more wide spread organ toxicity associated with the use of levamisole-adulterated cocaine

Immunohistochemical Analysis of IL-1 Receptor 1 In the Discs of Patients with Temporomandibular Joint Dysfunction

Objective Temporomandibular joint dysfunction (TMD) may affect a patient’s quality of life, and one of the etiologies can be anterior disc displacement with reduction (ADDwR) and anterior disc displacement without reduction (ADDWoR). Interleukin 1 Receptor 1 (IL-1R1) is a membrane receptor that plays an important role on initiating immune and inflammatory response by binding the agonists ligands of IL-1 alpha and IL-1 beta. Therefore, the aim of this study was to evaluate, through immunohistochemical analysis, the association of IL-1R1 with TMD. Methods Thirty-nine human disc samples were collected and composed three different groups: ADDwR (n = 19), ADDwoR (n = 12), and control group (n = 8). The samples were immunostained with IL-1R1 antibody and evaluated on both quantity and intensity of staining. Results There was a statistically significant difference (p \u3c 0.05) between the control and test groups for both quantity and intensity of staining. Conclusion IL1-R1 was associated with ADDwR and ADDwoR in TMD discs of humans

Queensland Stout Whiting Fishery 1991 TO 2002

The stout whiting (Sillago robusta) fishery in southern Queensland is restricted to offshore waters between Caloundra and Sandy Cape in depths ranging between 20 and 50 fathoms. The fishery consists of five licensed trawlers (T4 endorsement). The fishery is managed by means of a ‘industry agreed’ yearly Total Allowable Catch (TAC), which is reviewed annually and divided equally among the vessels. The TAC quota was set at 1000 tonnes for the managed area in 2002. The stout whiting resource was assessed using a newly developed age-structured model, along side with the previous virtual population and surplus production models. The new model was tuned simultaneously to standardised monthly-catch-rates and yearly patterns in the stout whiting catch age-structure. The limit reference point B/K (the ratio of exploitable biomass in 2002 to the exploitable component of the virgin carrying capacity) was estimated to be at about 0.19 (B/K less than 0.2 is generally accepted as high risk of over exploitation). The results from all three models should be viewed cautiously as their uncertainty is high. Given the high uncertainty, any increase in TAC above 1000 t has high risk. In the last four years total catch has varied between 1178 t and 498 t. This year’s assessment has shown no increase in recruitment and biomass after the catch levels of 881 t in 2000 and 855 t in 2002. The management strategy evaluation suggests this years TAC should range between 700t and 900t depending on the target management objectives of risk and yield from the fishery (Table 3.6). This Table 3.6 should be used to guide the decision on TAC setting and to understand how best to compromise the issues of risk (over fishing) and optimising yield (maximising catch and value in the fishery). Summary of the assessment is given in Table 1.1

Expression of Interleukin-1 and Temporomandibular Disorder: Contemporary Review of the Literature

Objective: Temporomandibular disorders (TMD) are a group of conditions affecting the temporomandibular joint (TMJ), leading to jaw dysfunction, joint and muscle pain, and a decrease in quality of life. A communication network of pro- and anti-inflammatory mediators called cytokines maintains the homeostasis of the TMJ. This review will focus on the Interleukin (IL) family of cytokines, which have been quantified in TMJ synovial fluids in a variety of studies. IL-1α and IL-1β have pro-inflammatory effects, while the endogenous receptor antagonist (IL-1RA) inhibits the pro-inflammatory effects of IL-1. Methods: A literature search (2006–2016) to identify eligible studies was completed using the PubMed database. Studies identified used saline irrigation to quantify cytokine profiles in synovial fluid of healthy and/or dysfunctional joints. Results: The initial search yielded 111 articles, 5 of which met the inclusion criteria after inter-reviewer discussion. Conclusions: Articles that compared IL-1 concentrations in TMD vs. control groups found significant differences

Forecasting intraspecific changes in distribution of a wide-ranging marine predator under climate change

Globally, marine animal distributions are shifting in response to a changing climate. These shifts are usually considered at the species level, but individuals are likely to differ in how they respond to the changing conditions. Here, we investigate how movement behaviour and, therefore, redistribution, would differ by sex and maturation class in a wide-ranging marine predator. We tracked 115 tiger sharks (Galeocerdo cuvier) from 2002 to 2020 and forecast class-specific distributions through to 2030, including environmental factors and predicted occurrence of potential prey. Generalised Linear and Additive Models revealed that water temperature change, particularly at higher latitudes, was the factor most associated with shark movements. Females dispersed southwards during periods of warming temperatures, and while juvenile females preferred a narrow thermal range between 22 and 23 degrees C, adult female and juvenile male presence was correlated with either lower ( 23 degrees C) temperatures. During La Nina, sharks moved towards higher latitudes and used shallower isobaths. Inclusion of predicted distribution of their putative prey significantly improved projections of suitable habitats for all shark classes, compared to simpler models using temperature alone. Tiger shark range off the east coast of Australia is predicted to extend similar to 3.5 degrees south towards the east coast of Tasmania, particularly for juvenile males. Our framework highlights the importance of combining long-term movement data with multi-factor habitat projections to identify heterogeneity within species when predicting consequences of climate change. Recognising intraspecific variability will improve conservation and management strategies and help anticipate broader ecosystem consequences of species redistribution due to ocean warming