Evaluation de la capacité de complexation des eaux naturelles de la rivière Saguenay, Canada

La rivière Saguenay est un affluent majeur du fleuve Saint-Laurent, Québec, Canada. La rivière Saguenay draine une région très industrialisée et se divise en deux sections : la section supérieure est peu profonde et constituée d'eau douce, tandis que la section en aval renferme un fjord profond caractérisé par une thermohalocline à environ 25 m. Nous avons caractérisé la capacité de complexation (CC) et la constante de stabilité critique (CSC) de ses eaux douces, dans la section supérieure de la rivière. Cinq différentes stations ont été échantillonnées le même jour; ces échantillons ont été fractionnés en fonction de la masse moléculaire nominale (NMM) des ligands dissous à l'aide de quatre colonnes de chromatographie par perméation de gel (GPC) Séphadex G-10, G-15, G-25 et G-50 utilisées en série. Pour les échantillons globaux, la CC diminue d'amont en aval passant de 0,32 à 0,14 µM. Nous n'avons pu identifier la cause de cette diminution qui pourrait être un simple effet de dilution ou une augmentation d'ions métalliques en solution. Une fois fractionnés, nous trouvons que la CC augmente avec NMM; par contre, la CC normalisée par unité de carbone est plus grande pour les ligands de plus faible NMM. Les CSC obtenues sont toutes similaires, environ 5 x 107 L mol-1, sauf pour les ligands ayant une NMM entre 700 et 1 800 g mol-1 avec une CSC de 27 x 107 L mol-1.The Saguenay River is a major affluent of the St. Lawrence River, Quebec, Canada. The Saguenay River which drains a heavily industrialized region can be subdivided into two sections: the upper section is rather shallow and contains freshwater as the lower one is a deep fjord characterized by a thermohalocline at about 25 m. This work aimed at identifying the possible modifications brought up by anthropogenic sources upon the complexation capacity of the freshwater of this River. Five different stations were sampled for surface water the same day on the upper section of the River. The samples were filtered on 0,4 µm membrane (pre-cleaned with HNO3). A portion was analyzed and other ones were fractionnated as a function of the nominal molecular mass (NMM) of dissolved ligands by using in series four gel permeation chromatographic (GPC) columns filled with Sephadex G-10, G-15, G-25 and G-50 respectively, the elution being dope by purified 18MOhms water. The complexation capacity (CC) and critical stability constant (CSC) of the different fractions have been characterized using a method based on free Cu2+ back-titration by Differential Pulsed Anodic Stripping Voltammetry (DPASV) and a 1:1 complexation scheme. Because copper was giving two unresolved peaks on the tailing of the oxygen peak, all polarograms have been deconvolved by a PASCAL computer program based on a least-sqares nonlinear fit using the Taylor differential correction technique. All results compiled were from the peak centered at - 60 mV against an Ag/AgCl reference. By manipulating the usual equations to determine CC and CSC with the free Cu2+ back-titration, we were able to calculate CC by three different routes and CSC by two different routes ; when enough reliable data were available for each route, all values obtained were concordant. So we observed that, going downstream, the CC decreased from 0,32 to 0,14 µM for whole samples. At this point, we cannot identity the cause of this decrease wether it is due to simple dilution or by addition of new dissolved metallic ions into the stream. Once fractionnated, CC measured was seen increasing with NMM but normalized CC per unit of carbon has been found to be greater for ligands with small NMM (normalized CC decreased with increasing NMM). The CSC obtained were all similar, about 5 x 107 L mol-1, excepted for ligands with NMM between 700 and 1 800 g mol-1, the CSC being 27 x 107 L mol-1 from the inverse linearized method

Extracellular sheath formation by Sphaeropsis hypodermia and association with its infection in elm trees

Nous avons observé le mode de développement de Sphaeropsis hypodermia (isolé d'une branche d'orme (Ulmus americana) atteinte d'un chancre) dans les milieux suivants : un milieu gélosé (PDA), un tissu essuie-tout (Kimwipes), des blocs de bois d'orme stérilisés à l'autoclave, et des ormes d'Amérique inoculés en serre. Des échantillons de chaque substrat ont été fixés pour les observations en microscopie photonique et en microscopie électronique avec du glutaraldéhyde et du tétroxyde d'osmium. Observés en microscopie électronique, les hyphes accolés au substrat étaient entourés d'une épaisse couche extracellulaire devenant circonscrite par des bandes rigides et contenant des corps opaques simples ou agrégés, ou des masses de matière opaque plus volumineuses dans le cas des blocs de bois d'orme. Sur celui-ci et sur le tissu Kimwipes, la couche extracellulaire s'étendait sur une distance appréciable, loin des cellules fongiques, et avait également pénétré les parois de cellules de parenchyme et des fibres, selon le cas. Dans les ormes inoculés, le champignon a rapidement produit des dommages notables dans les tissus du cambium et colonisé abondamment les régions de l'écorce et du xylème avoisinantes. La pénétration et la dégradation des parois cellulaires de l'écorce étaient marquées, en relation également avec de la matière opaque entourant les cellules du champignon. Cette matière ressemblait à celle liée aux cellules fongiques sur les milieux stérilisés. Bien que les cellules du xylème étaient généralement colonisées, des altérations pariétales n'étaient apparentes que dans les cellules récemment formées. En outre, le passage du champignon d'une cellule à l'autre à travers les parois n'a été observé que dans le cas des éléments de vaisseaux et des cellules de rayon. Concernant les fibres, seule y était visible une bande de matière filamenteuse dans les parois et liant les cellules fongiques présentes dans la lumière de ces fibres. En réponse à la dégradation de parois cellulaires liée à de la matière opaque, l'hypertrophie et l'hyperplasie des cellules du cambium et de l'écorce interne ont été observées, liées possiblement à la formation d'une barrière de protection. On discute du rôle possible de la couche extracellulaire des cellules fongiques in vivo et in vitro.Sphaeropsis hypodermia, isolated from a cankered American elm branch, was grown on agar medium (PDA), on autoclaved wiping paper (Kimwipes), and American elm (Ulmus americana) wood chips, or inoculated into greenhouse-grown American elm saplings. Samples from each treatment were double-fixed with glutaraldehyde and osmium tetroxide and examined with the light and the transmission electron microscopes. Ultrastructurally, the hyphae on PDA and inert substrates appeared surrounded by large extracellular sheaths which were delimited by rigid opaque bands of various thicknesses. The sheaths extended appreciable distances from the fungal cells, as evidenced by their adherence to rigid substrates. Individual or aggregated opaque bodies, even as large masses on elm wood chips, were the main components of the sheath. This opaque material was often associated with penetration and ruptures of the wood cells. Inoculated into elm trees, the fungus rapidly caused pronounced alterations of cambial tissues and colonized the adjoining bark and xylem cells. The prominent penetration and breakdown of the inner and outer bark cells by the fungus were associated with opaque material, particularly in cortical fibres. The material was structurally similar to the sheath formed on the rigid sterilized substrates. In the xylem, only the walls of the recently deposited cells were visibly altered, and although mature fibres were generally colonized, the passage of the fungus from one fibre to another was rarely observed, contrary to the passage from vessel and ray cells to adjoining cells. In that instance, only bands of opaque material present in the walls of fibres were connected with fungal cells in their lumen. In the inner bark and cambial regions, cell hypertrophy and hyperplasia occurred next to host walls that were altered and contained similar opaque material. The extracellular sheath of S. hypodermia under in vitro conditions and the opaque material associated with host wall alterations in vivo are considered to be analogous

Flipping quantum coins

Coin flipping is a cryptographic primitive in which two distrustful parties wish to generate a random bit in order to choose between two alternatives. This task is impossible to realize when it relies solely on the asynchronous exchange of classical bits: one dishonest player has complete control over the final outcome. It is only when coin flipping is supplemented with quantum communication that this problem can be alleviated, although partial bias remains. Unfortunately, practical systems are subject to loss of quantum data, which restores complete or nearly complete bias in previous protocols. We report herein on the first implementation of a quantum coin-flipping protocol that is impervious to loss. Moreover, in the presence of unavoidable experimental noise, we propose to use this protocol sequentially to implement many coin flips, which guarantees that a cheater unwillingly reveals asymptotically, through an increased error rate, how many outcomes have been fixed. Hence, we demonstrate for the first time the possibility of flipping coins in a realistic setting. Flipping quantum coins thereby joins quantum key distribution as one of the few currently practical applications of quantum communication. We anticipate our findings to be useful for various cryptographic protocols and other applications, such as an online casino, in which a possibly unlimited number of coin flips has to be performed and where each player is free to decide at any time whether to continue playing or not.Comment: 17 pages, 3 figure

Fair Loss-Tolerant Quantum Coin Flipping

Coin flipping is a cryptographic primitive in which two spatially separated players, who in principle do not trust each other, wish to establish a common random bit. If we limit ourselves to classical communication, this task requires either assumptions on the computational power of the players or it requires them to send messages to each other with sufficient simultaneity to force their complete independence. Without such assumptions, all classical protocols are so that one dishonest player has complete control over the outcome. If we use quantum communication, on the other hand, protocols have been introduced that limit the maximal bias that dishonest players can produce. However, those protocols would be very difficult to implement in practice because they are susceptible to realistic losses on the quantum channel between the players or in their quantum memory and measurement apparatus. In this paper, we introduce a novel quantum protocol and we prove that it is completely impervious to loss. The protocol is fair in the sense that either player has the same probability of success in cheating attempts at biasing the outcome of the coin flip. We also give explicit and optimal cheating strategies for both players.Comment: 12 pages, 1 figure; various minor typos corrected in version

Professional barriers and facilitators to using stratified care approaches for managing non-specific low back pain: a qualitative study with Canadian physiotherapists and chiropractors

Background: Recent clinical practice guidelines for the management of non-specific low back pain (LBP) recommend using stratified care approaches. To date, no study has assessed barriers and facilitators for health professionals in using stratified care approaches for managing non-specific LBP in the Canadian primary care setting. This study aimed to identify and contrast barriers and facilitators to using the stratified care approaches for non-specific LBP among Canadian physiotherapists and chiropractors. Methods: Individual telephone interviews, underpinned by the Theoretical Domains Framework (TDF), explored beliefs and attitudes about, and identified barriers and facilitators to the use of stratified care approaches for managing non-specific LBP in a purposive sample of 13 chiropractors and 14 physiotherapists between September 2015 and June 2016. Interviews were digitally recorded, transcribed verbatim and analysed by two independent assessors using directed content analysis. Results: Three and seven TDF domains were identified as likely relevant for physiotherapists and chiropractors, respectively. Shared key beliefs (and relevant domains of the TDF) for both physiotherapists and chiropractors included: lack of time, cost, and expertise (Environmental Context and Resources); and consulting more experienced colleagues and chronic patients with important psychological overlay (Social Influences). Unique key domains were identified among physiotherapists: incompatibility with achieving other objectives (Goals), and chiropractors: confidence in using stratified care approaches (Beliefs about Capabilities); intention to use stratified care approaches (Intentions); awareness and agreement with stratified care approaches (Knowledge); assessment of readiness for change and intentional planning behaviour (Behavioural Regulation); and improving the management of non-specific LBP patients and the uptake of evidence-based practice (Beliefs about Consequences). Conclusions: Several shared and unique barriers and facilitators to using the stratified care approaches for non-specific LBP among Canadian physiotherapists and chiropractors were identified. Findings may help inform the design of tailored theory-based knowledge translation interventions to increase the uptake of stratified care approaches in clinical practice. © The Author(s). 2019

High-efficiency WSi superconducting nanowire single-photon detectors operating at 2.5 K

We investigate the operation of WSi superconducting nanowire single-photon detectors (SNSPDs) at 2.5 K, a temperature which is ~ 70 % of the superconducting transition temperature (TC) of 3.4 K. We demonstrate saturation of the system detection efficiency at 78 +- 2 % with a jitter of 191 ps. We find that the jitter at 2.5 K is limited by the noise of the readout, and can be improved through the use of cryogenic amplifiers. Operation of SNSPDs with high efficiency at temperatures very close to TC appears to be a unique property of amorphous WSi

High-efficiency superconducting nanowire single-photon detectors fabricated from MoSi thin-films

We demonstrate high-efficiency superconducting nanowire single-photon detectors (SNSPDs) fabricated from MoSi thin-films. We measure a maximum system detection efficiency (SDE) of 87 +- 0.5 % at 1542 nm at a temperature of 0.7 K, with a jitter of 76 ps, maximum count rate approaching 10 MHz, and polarization dependence as low as 3.4 +- 0.7 % The SDE curves show saturation of the internal efficiency similar to WSi-based SNSPDs at temperatures as high as 2.3 K. We show that at similar cryogenic temperatures, MoSi SNSPDs achieve efficiencies comparable to WSi-based SNSPDs with nearly a factor of two reduction in jitter

Identifying factors likely to influence compliance with diagnostic imaging guideline recommendations for spine disorders among chiropractors in North America: a focus group study using the Theoretical Domains Framework

Background: The Theoretical Domains Framework (TDF) was developed to investigate determinants of specific clinical behaviors and inform the design of interventions to change professional behavior. This framework was used to explore the beliefs of chiropractors in an American Provider Network and two Canadian provinces about their adherence to evidence-based recommendations for spine radiography for uncomplicated back pain. The primary objective of the study was to identify chiropractors’ beliefs about managing uncomplicated back pain without xrays and to explore barriers and facilitators to implementing evidence-based recommendations on lumbar spine xrays. A secondary objective was to compare chiropractors in the United States and Canada on their beliefs regarding the use of spine x-rays. Methods: Six focus groups exploring beliefs about managing back pain without x-rays were conducted with a purposive sample. The interview guide was based upon the TDF. Focus groups were digitally recorded, transcribed verbatim, and analyzed by two independent assessors using thematic content analysis based on the TDF. Results: Five domains were identified as likely relevant. Key beliefs within these domains included the following: conflicting comments about the potential consequences of not ordering x-rays (risk of missing a pathology, avoiding adverse treatment effects, risks of litigation, determining the treatment plan, and using x-ray-driven techniques contrasted with perceived benefits of minimizing patient radiation exposure and reducing costs; beliefs about consequences); beliefs regarding professional autonomy, professional credibility, lack of standardization, and agreement with guidelines widely varied (social/professional role & identity); the influence of formal training, colleagues, and patients also appeared to be important factors (social influences); conflicting comments regarding levels of confidence and comfort in managing patients without x-rays (belief about capabilities); and guideline awareness and agreements (knowledge). Conclusions: Chiropractors’ use of diagnostic imaging appears to be influenced by a number of factors. Five key domains may be important considering the presence of conflicting beliefs, evidence of strong beliefs likely to impact the behavior of interest, and high frequency of beliefs. The results will inform the development of a theorybased survey to help identify potential targets for behavioral-change strategies