Crowd-Validated CAPTCHAs and Content Verification

Social media, rating systems, trending news, and other online information sources rely on bona fide human contributors in order to function accurately and retain trust amongst information consumers. Inaccurate or false content, quickly and widely disseminated by bots, can cause erosion of trust in these platforms and have wider ramifications. This disclosure describes techniques to generate CAPTCHA challenges that are difficult, and nearly impossible, for bots to solve. The challenges comprise gestural, emotive, or cognitive micro-tasks that involve physical interaction of the challenge-taker with multiple UI modes such as camera, touchscreen, etc

Assessing Potential Change in Louisiana Juvenile Detainee’s Knowledge and Attitude during Garden Programming

University-based horticulture departments have explored the relationship between garden programs and increased horticulture knowledge among primary and secondary students. Studies have established positive correlations between youth garden programs and increased garden knowledge. The objective of this research was to determine if participation in a garden workshop series had positive effects on youth detained in juvenile detention centers garden-based knowledge and immediate mood. Participation led to a 17% increase in garden-based knowledge (P ? 0.05) and a positive shift in mood (P ? 0.05) on two of the three days of the workshop series. Based on this experience, we highly recommend juvenile detention centers incorporate garden programming as additional educational opportunities for detained youth

Mission description and in-flight operations of ERBE instruments on ERBS and NOAA 9 spacecraft, November 1984 - January 1986

Instruments of the Earth Radiation Budget Experiment (ERBE) are operating on three different Earth orbiting spacecrafts: the Earth Radiation Budget Satellite (ERBS), NOAA-9, and NOAA-10. An overview is presented of the ERBE mission, in-orbit environments, and instrument design and operational features. An overview of science data processing and validation procedures is also presented. In-flight operations are described for the ERBE instruments aboard the ERBS and NOAA-9. Calibration and other operational procedures are described, and operational and instrument housekeeping data are presented and discussed

Mission description and in-flight operations of ERBE instruments on ERBS, NOAA 9, and NOAA 10 spacecraft

Instruments of the Earth Radiation Budget Experiment (ERBE) are operating on three different Earth-orbiting spacecraft. The Earth Radiation Budget Satellite (ERBS) is operated by NASA, and NOAA 9 and NOAA 10 weather satellites are operated by the National Oceanic and Atmospheric Administration (NOAA). This paper is the second in a series that describes the ERBE mission, and data processing and validation procedures. This paper describes the spacecraft and instrument operations for the second full year of in-orbit operations, which extend from February 1986 through January 1987. Validation and archival of radiation measurements made by ERBE instruments during this second year of operation were completed in July 1991. This period includes the only time, November 1986 through January 1987, during which all ERBE instruments aboard the ERBE, NOAA 9, and NOAA 10 spacecraft were simultaneously operational. This paper covers normal and special operations of the spacecraft and instruments, operational anomalies, and the responses of the instruments to in-orbit and seasonal variations in the solar environment

Mission Description and In-Flight Operations of ERBE Instruments on ERBS, NOAA 9, and NOAA 10 Spacecraft

Instruments of the Earth Radiation Budget Experiment (ERBE) have operated on three different Earth-orbiting spacecraft. The Earth Radiation Budget Satellite (ERBS) is operated by the National Aeronautics and Space Administration (NASA), and the NOAA 9 and NOAA 10 weather satellites are operated by the National Oceanic and Atmospheric Administration (NOAA). This paper is one of a series that describes the ERBE mission, in-orbit environments, instrument design and operational features, and data processing and validation procedures. This paper also describes the in-flight operations for the ERBE nonscanner instruments aboard the ERBS, NOAA 9, and NOAA 10 spacecraft from January 1990 through December 1990. Validation and archives of radiation measurements made by ERBE nonscanner instruments during this period were completed in August 1996. This paper covers normal and special operations of the spacecraft and instruments, operational anomalies, and the responses of the instruments to in-orbit and seasonal variations in the solar environment

Re-Examination of the Observed Decadal Variability of Earth Radiation Budget Using Altitude-Corrected ERBE/ERBS Nonscanner WFOV Data

This paper gives an update on the observed decadal variability of Earth Radiation Budget using the latest altitude-corrected Earth Radiation Budget Experiment (ERBE)/Earth Radiation Budget Satellite (ERBS) Nonscanner Wide Field of View (WFOV) instrument Edition3 dataset. The effects of the altitude correction are to modify the original reported decadal changes in tropical mean (20N to 20S) longwave (LW), shortwave (SW), and net radiation between the 1980s and the 1990s from 3.1/-2.4/-0.7 to 1.6/-3.0/1.4 Wm(sup -2) respectively. In addition, a small SW instrument drift over the 15-year period was discovered during the validation of the WFOV Edition3 dataset. A correction was developed and applied to the Edition3 dataset at the data user level to produce the WFOV Edition3_Rev1 dataset. With this final correction, the ERBS Nonscanner observed decadal changes in tropical mean LW, SW, and net radiation between the 1980s and the 1990s now stand at 0.7/-2.1/1.4 Wm(sup -2), respectively, which are similar to the observed decadal changes in the HIRS Pathfinder OLR and the ISCCP FD record; but disagree with the AVHRR Pathfinder ERB record. Furthermore, the observed interannual variability of near-global ERBS WFOV Edition3_Rev1 net radiation is found to be remarkably consistent with the latest ocean heat storage record for the overlapping time period of 1993 to 1999. Both data sets show variations of roughly 1.5 Wm(sup -2) in planetary net heat balance during the 1990s

Drug prescriptions and dementia incidence: a medication-wide association study of 17000 dementia cases among half a million participants

Previous studies have suggested that some medications may influence dementia risk. We conducted a hypothesis-generating medication-wide association study to investigate systematically the association between all prescription medications and incident dementia. We used a population-based cohort within the Secure Anonymised Information Linkage (SAIL) databank, comprising routinely-collected primary care, hospital admissions and mortality data from Wales, UK. We included all participants born after 1910 and registered with a SAIL general practice at ≤60 years old. Follow-up was from each participant's 60th birthday to the earliest of dementia diagnosis, deregistration from a SAIL general practice, death or the end of 2018. We considered participants exposed to a medication if they received ≥1 prescription for any of 744 medications before or during follow-up. We adjusted for sex, smoking and socioeconomic status. The outcome was any all-cause dementia code in primary care, hospital or mortality data during follow-up. We used Cox regression to calculate hazard ratios and Bonferroni-corrected p values. Of 551 344 participants, 16 998 (3%) developed dementia (median follow-up was 17 years for people who developed dementia, 10 years for those without dementia). Of 744 medications, 221 (30%) were associated with dementia. Of these, 217 (98%) were associated with increased dementia incidence, many clustering around certain indications. Four medications (all vaccines) were associated with a lower dementia incidence. Almost a third of medications were associated with dementia. The clustering of many drugs around certain indications may provide insights into early manifestations of dementia. We encourage further investigation of hypotheses generated by these results. [Abstract copyright: © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ.

Influence of neighborhood-level socioeconomic deprivation and individual socioeconomic position on risk of developing type 2 diabetes in older men: a longitudinal analysis in the British Regional Heart Study cohort

INTRODUCTION: Evidence from longitudinal studies on the influence of neighborhood socioeconomic deprivation in older age on the development of type 2 diabetes mellitus (T2DM) is limited. This study investigates the prospective associations of neighborhood-level deprivation and individual socioeconomic position (SEP) with T2DM incidence in older age. RESEARCH DESIGN AND METHODS: The British Regional Heart Study studied 4252 men aged 60-79 years in 1998-2000. Neighborhood-level deprivation was based on the Index of Multiple Deprivation quintiles for participants' 1998-2000 residential postcode. Individual SEP was defined as social class based on longest-held occupation. A cumulative score of individual socioeconomic factors was derived. Incident T2DM cases were ascertained from primary care records; prevalent cases were excluded. Cox proportional hazard models were used to examine the associations. RESULTS: Among 3706 men, 368 incident cases of T2DM were observed over 18 years. The age-adjusted T2DM risk increased from the least deprived quintile to the most deprived: HR per quintile increase 1.14 (95% CI 1.06 to 1.23) (p=0.0005). The age-adjusted T2DM HR in social class V (lowest) versus social class I (highest) was 2.45 (95% CI 1.36 to 4.42) (p=0.001). Both associations attenuated but remained significant on adjustment for other deprivation measures, becoming non-significant on adjustment for body mass index and T2DM family history. T2DM risk increased with cumulative individual adverse socioeconomic factors: HR per point increase 1.14 (95% CI 1.05 to 1.24). CONCLUSIONS: Inequalities in T2DM risk persist in later life, both in relation to neighborhood-level and individual-level socioeconomic factors. Underlying modifiable risk factors continue to need to be addressed in deprived older age populations to reduce disease burden

Children’s Oxygen Administration Strategies Trial (COAST): A randomised controlled trial of high flow versus oxygen versus control in African children with severe pneumonia.

Background: In Africa, the clinical syndrome of pneumonia remains the leading cause of morbidity and mortality in children in the post-neonatal period. This represents a significant burden on in-patient services. The targeted use of oxygen and simple, non-invasive methods of respiratory support may be a highly cost-effective means of improving outcome, but the optimal oxygen saturation threshold that results in benefit and the best strategy for delivery are yet to be tested in adequately powered randomised controlled trials. There is, however, an accumulating literature about the harms of oxygen therapy across a range of acute and emergency situations that have stimulated a number of trials investigating permissive hypoxia. Methods: In 4200 African children, aged 2 months to 12 years, presenting to 5 hospitals in East Africa with respiratory distress and hypoxia (oxygen saturation \u3c 92%), the COAST trial will simultaneously evaluate two related interventions (targeted use of oxygen with respect to the optimal oxygen saturation threshold for treatment and mode of delivery) to reduce shorter-term mortality at 48-hours (primary endpoint), and longer-term morbidity and mortality to 28 days in a fractional factorial design, that compares: Liberal oxygenation (recommended care) compared with a strategy that permits hypoxia to SpO2 \u3e or = 80% (permissive hypoxia); and High flow using AIrVO2TM compared with low flow delivery (routine care). Discussion: The overarching objective is to address the key research gaps in the therapeutic use of oxygen in resource-limited setting in order to provide a better evidence base for future management guidelines. The trial has been designed to address the poor outcomes of children in sub-Saharan Africa, which are associated with high rates of in-hospital mortality, 9-10% (for those with oxygen saturations of 80-92%) and 26-30% case fatality for those with oxygen saturations \u3c80%