Children with FASD- Related Disabilities Receiving Services from Child Welfare Agencies in Manitoba

Fetal Alcohol Spectrum Disorder (FASD) is a serious social and health problem for the child welfare, health and education systems in North America and other parts of the world. This article describes the population of children in care of the child welfare system in Manitoba. Also this article will highlight the relevance of these research findings to aboriginal populations in Canada and its implications for international aboriginal/ indigenous groups. Finally, the implications for policy, practice are discussed and the article puts forward some directions for further research

What Have We Learnt About CO2 Leakage in the Context of Commercial-Scale CCS?

The viability of Carbon Capture and Storage (CCS) depends on the reliable containment of injected CO2 in the subsurface. Robust and cost-effective approaches to measure monitor and verify CO2 containment are required to demonstrate that CO2 has not breached the reservoir, and to comply with CCS regulations. This includes capability to detect and quantify any potential leakage to surface. It is useful to consider the range of possible leak rates for potential CO2 leak pathways from an intended storage reservoir to surface to inform the design of effective monitoring approaches. However, in the absence of a portfolio of leakage from engineered CO2 stores we must instead learn from industrial and natural analogues, numerical models, and laboratory and field experiments that have intentionally released CO2 into the shallow subsurface to simulate a CO2 leak to surface. We collated a global dataset of measured or estimated CO2 flux (CO2 emission per unit area) and CO2 leak rate from industrial and natural analogues and field experiments. We then examined the dataset to compare emission and flux rates and seep style, and consider the measured emission rates in the context of commercial scale CCS operations. We find that natural and industrial analogues show very wide variation in the scale of CO2 emissions, and tend to be larger than leaks simulated by CO2 release experiments. For all analogue types (natural, industrial, or experiment) the emission rates show greater variation between sites than CO2 flux rates. Quantitation approaches are non-standardized, and that measuring and reporting both the CO2 flux and seep rate is rare as it remains challenging, particularly in marine environments. Finally, we observe that CO2 fluxes tend to be associated with particular emission characteristics (vent, diffuse, or water-associated). We propose that characteristics could inform the design and performance requirements for CO2 leak monitoring approaches tailored to detect specific emission styles

What have we learnt about CO2 leakage in the context of commercial-scale CCS?

The viability of Carbon Capture and Storage (CCS) depends on the reliable containment of injected CO2 in the subsurface. Robust and cost-effective approaches to measure monitor and verify CO2 containment are required to demonstrate that CO2 has not breached the reservoir, and to comply with CCS regulations. This includes capability to detect and quantify any potential leakage to surface. It is useful to consider the range of possible leak rates for potential CO2 leak pathways from an intended storage reservoir to surface to inform the design of effective monitoring approaches. However, in the absence of a portfolio of leakage from engineered CO2 stores we must instead learn from industrial and natural analogues, numerical models, and laboratory and field experiments that have intentionally released CO2 into the shallow subsurface to simulate a CO2 leak to surface. We collated a global dataset of measured or estimated CO2 flux (CO2 emission per unit area) and CO2 leak rate from industrial and natural analogues and field experiments. We then examined the dataset to compare emission and flux rates and seep style, and consider the measured emission rates in the context of commercial scale CCS operations. We find that natural and industrial analogues show very wide variation in the scale of CO2 emissions, and tend to be larger than leaks simulated by CO2 release experiments. For all analogue types (natural, industrial, or experiment) the emission rates show greater variation between sites than CO2 flux rates. Quantitation approaches are non-standardized, and that measuring and reporting both the CO2 flux and seep rate is rare as it remains challenging, particularly in marine environments. Finally, we observe that CO2 fluxes tend to be associated with particular emission characteristics (vent, diffuse, or water-associated). We propose that characteristics could inform the design and performance requirements for CO2 leak monitoring approaches tailored to detect specific emission styles

Section E6.1–6.4 of the ACMG technical standards and guidelines: chromosome studies of neoplastic blood and bone marrow–acquired chromosomal abnormalities

DISCLAIMER: These American College of Medical Genetics and Genomics standards and guidelines are developed primarily as an educational resource for clinical laboratory geneticists to help them provide quality clinical laboratory genetic services. Adherence to these standards and guidelines is voluntary and does not necessarily ensure a successful medical outcome. These standards and guidelines should not be considered inclusive of all proper procedures and tests or exclusive of other procedures and tests that are reasonably directed to obtaining the same results. In determining the propriety of any specific procedure or test, the clinical laboratory geneticist should apply his or her own professional judgment to the specific circumstances presented by the individual patient or specimen. Clinical laboratory geneticists are encouraged to document in the patient's record the rationale for the use of a particular procedure or test, whether or not it is in conformance with these standards and guidelines. They also are advised to take notice of the date any particular guideline was adopted, and to consider other relevant medical and scientific information that becomes available after that date. It also would be prudent to consider whether intellectual property interests may restrict the performance of certain tests and other procedures.Cytogenetic analyses of hematological neoplasms are performed to detect and characterize clonal chromosomal abnormalities that have important diagnostic, prognostic, and therapeutic implications. At the time of diagnosis, cytogenetic abnormalities assist in the diagnosis of such disorders and can provide important prognostic information. At the time of relapse, cytogenetic analysis can be used to confirm recurrence of the original neoplasm, detect clonal disease evolution, or uncover a new unrelated neoplastic process. This section deals specifically with the standards and guidelines applicable to chromosome studies of neoplastic blood and bone marrow-acquired chromosomal abnormalities. This updated Section E6.1-6.4 has been incorporated into and supersedes the previous Section E6 in Section E: Clinical Cytogenetics of the 2009 Edition (Revised 01/2010), American College of Medical Genetics and Genomics Standards and Guidelines for Clinical Genetics Laboratories.Genet Med 18 6, 635-642

RS-34 Phoenix In-Space Propulsion System Applied to Active Debris Removal Mission

No abstract availabl

Bound by the clock: The experiences of youth with FASD transitioning to adulthood from child welfare care

Fetal Alcohol Spectrum Disorder (FASD) is a condition that affects a significant proportion of children and youth in the care of child welfare agencies in Canada. Few studies have heard from the voices of youth with FASD themselves as they are leaving care. This article describes a qualitative study that focuses on the lived experiences of 20 youth with FASD in Manitoba as they were preparing for the transition from child welfare care to adulthood (or had recently emancipated from the system). The experiences and insights of these youth highlight the supports and services required by youth with FASD transitioning out of care, from both the child welfare system and from services for adults with FASD