Approximations of thermoelastic and viscoelastic control systems

Well-posed models and computational algorithms are developed and analyzed for control of a class of partial differential equations that describe the motions of thermo-viscoelastic structures. An abstract (state space) framework and a general well-posedness result are presented that can be applied to a large class of thermo-elastic and thermo-viscoelastic models. This state space framework is used in the development of a computational scheme to be used in the solution of a linear quadratic regulator (LQR) control problem. A detailed convergence proof is provided for the viscoelastic model and several numerical results are presented to illustrate the theory and to analyze problems for which the theory is incomplete

The F220C and F45L rhodopsin mutations identified in retinitis pigmentosa patients do not cause pathology in mice.

Retinitis pigmentosa is a retinal degenerative disease that leads to blindness through photoreceptor loss. Rhodopsin is the most frequently mutated protein in this disease. While many rhodopsin mutations have well-understood consequences that lead to cell death, the disease association of several rhodopsin mutations identified in retinitis pigmentosa patients, including F220C and F45L, has been disputed. In this study, we generated two knockin mouse lines bearing each of these mutations. We did not observe any photoreceptor degeneration in either heterozygous or homozygous animals of either line. F220C mice exhibited minor disruptions of photoreceptor outer segment dimensions without any mislocalization of outer segment proteins, whereas photoreceptors of F45L mice were normal. Suction electrode recordings from individual photoreceptors of both mutant lines showed normal flash sensitivity and photoresponse kinetics. Taken together, these data suggest that neither the F220C nor F45L mutation has pathological consequences in mice and, therefore, may not be causative of retinitis pigmentosa in humans

Individual-based Modeling of Genome Evolution in Haplodiploid Organisms

Ants, bees, wasps, bark beetles, and other species have haploid males and diploid females. Although such haplodiploid species play key ecological roles and are threatened by environmental changes, no general framework exists for simulating their genetic evolution. Here, we use the SLiM simulation environment to build a novel model for individual-based forward simulation of genetic evolution in haplodiploids. We compare the fates of adaptive and deleterious mutations and find that selection on recessive mutations is more effective in haplodiploids than in diploids. Our open-source model will foster an understanding of the evolution of sociality and how ecologically important haplodiploid species may respond to changing environments

Astrometry of OH/IR stars using 1612 MHz hydroxyl masers. I. Annual parallaxes of WX Psc and OH138.0+7.2

We report on the measurement of the trigonometric parallaxes of 1612 MHz hydroxyl masers around two asymptotic giant branch stars, WX Psc and OH138.0+7.2, using the NRAO Very Long Baseline Array with in-beam phase referencing calibration. We obtained a 3-sigma upper limit of <=5.3 mas on the parallax of WX Psc, corresponding to a lower limit distance estimate of >~190 pc. The obtained parallax of OH138.0+7.2 is 0.52+/-0.09 mas (+/-18%), corresponding to a distance of 1.9(+0.4,-0.3) kpc, making this the first hydroxyl maser parallax below one milliarcsecond. We also introduce a new method of error analysis for detecting systematic errors in the astrometry. Finally, we compare our trigonometric distances to published phase-lag distances toward these stars and find a good agreement between the two methods.Comment: Preprint, accepted for publication in The Astronomical Journal (January 17, 2017

An Optimal Self-Stabilizing Firing Squad

Consider a fully connected network where up to $t$ processes may crash, and all processes start in an arbitrary memory state. The self-stabilizing firing squad problem consists of eventually guaranteeing simultaneous response to an external input. This is modeled by requiring that the non-crashed processes "fire" simultaneously if some correct process received an external "GO" input, and that they only fire as a response to some process receiving such an input. This paper presents FireAlg, the first self-stabilizing firing squad algorithm. The FireAlg algorithm is optimal in two respects: (a) Once the algorithm is in a safe state, it fires in response to a GO input as fast as any other algorithm does, and (b) Starting from an arbitrary state, it converges to a safe state as fast as any other algorithm does.Comment: Shorter version to appear in SSS0

Mass and Metallicity of Five X-ray Bright Galaxy Groups

We present ASCA X-ray observations of a sample of five groups selected from a cross-correlation of the ROSAT All-Sky Survey with the White et al. optical catalog of groups. These X-ray bright groups significantly increase the number of known systems with temperatures between 2 and 3 keV. They have element abundances of roughly 0.3 times solar that are typical of clusters, but their favored ratio of Si/Fe abundance is lower than the cluster value. Combining the ASCA results with ROSAT imaging data, we calculate total masses of a few to several times 10^13 M_sun, gas mass fractions of ~10%, and baryonic mass fractions of at least 15-20% within a radius of 0.5 Mpc. Upper limits for the ratios of gas to galaxy mass and of the iron mass to galaxy luminosity overlap with the range observed in rich clusters and extend to lower values, but not to such low values as seen in much poorer groups. These results support the idea that groups, unlike clusters, are subject to the loss of their primordial and processed gas, and show that this transition occurs at the mass scale of the 2-3 keV groups. A discussion of ASCA calibration issues and a comparison of ROSAT and ASCA temperatures are included in an Appendix

Potential and challenges in collecting social and behavioral data on adolescent alcohol norms: Comparing respondent-driven sampling and web-based respondent-driven sampling

Background: Respondent-driven sampling (RDS) is a method successfully used to research hard-to-access populations. Few studies have explored the use of the Internet and social media with RDS, known as Web-based RDS (WebRDS). This study explored the use of combining both "traditional" RDS and WebRDS to examine the influences on adolescent alcohol use. Objective: This paper reports on the recruitment processes and the challenges and enablers of both RDS and WebRDS. It details comparative recruitment data and provides a summary of the utility of both methods for recruiting adolescents to participate in an online survey investigating youth alcohol norms. Methods: Process evaluation data collected from research staff throughout the study were used to assess the challenges and solutions of RDS and WebRDS. Pearson chi-square test (Fisher's exact test if applicable) was used to compare the differences in sociodemographics and drinking behavior between data collected by RDS and WebRDS. Results: Of the total sample (N=1012), 232 adolescents were recruited by RDS and 780 by WebRDS. A significantly larger proportion of Aboriginal or Torres Strait Islander (P&lt;.001) participants who spoke English as their main language at home (P=.03), and of middle and lower socioeconomic status (P&lt;.001) was found in the RDS sample. The RDS sample was also found to have a higher occurrence of past 7-day drinking (P&lt;.001) and past 7-day risky drinking (P=.004). No significant differences in gender, age, past month alcohol use, and lifetime alcohol use were observed between the RDS and WebRDS samples. This study revealed RDS and WebRDS used similar lengths of chains for recruiting participants; however, WebRDS conducted a faster rate of recruitment at a lower average cost per participant compared to RDS. Conclusions: Using WebRDS resulted in significant improvements in the recruitment rate and was a more effective and efficient use of resources than the traditional RDS method. However, WebRDS resulted in partially different sample characteristics to traditional RDS. This potential effect should be considered when selecting the most appropriate data collection method

The Carnegie Supernova Project I: methods to estimate host-galaxy reddening of stripped-envelope supernovae

We aim to improve upon contemporary methods to estimate host-galaxy reddening of stripped-envelope (SE) supernovae (SNe). To this end the Carnegie Supernova Project (CSP-I) SE SNe photometry data release, consisting of nearly three dozen objects, is used to identify a minimally reddened sub-sample for each traditionally defined spectroscopic sub-types (i.e, SNe~IIb, SNe~Ib, SNe~Ic). Inspection of the optical and near-infrared (NIR) colors and color evolution of the minimally reddened sub-samples reveals a high degree of homogeneity, particularly between 0d to +20d relative to B-band maximum. This motivated the construction of intrinsic color-curve templates, which when compared to the colors of reddened SE SNe, yields an entire suite of optical and NIR color excess measurements. Comparison of optical/optical vs. optical/NIR color excess measurements indicates the majority of the CSP-I SE SNe suffer relatively low amounts of reddening and we find evidence for different R_(V)^(host) values among different SE SN. Fitting the color excess measurements of the seven most reddened objects with the Fitzpatrick (1999) reddening law model provides robust estimates of the host visual-extinction A_(V)^(host) and R_(V)^(host). In the case of the SE SNe with relatively low amounts of reddening, a preferred value of R_(V)^(host) is adopted for each sub-type, resulting in estimates of A_(V)^(host) through Fitzpatrick (1999) reddening law model fits to the observed color excess measurements. Our analysis suggests SE SNe reside in galaxies characterized by a range of dust properties. We also find evidence SNe Ic are more likely to occur in regions characterized by larger R_(V)^(host) values compared to SNe IIb/Ib and they also tend to suffer more extinction. These findings are consistent with work in the literature suggesting SNe Ic tend to occur in regions of on-going star formation.Comment: Abstract abridged to fit allowed limit. Resubmitted to A&A, 34 pages, 19 figures, 6 tables. Constructive comments welcome