575 research outputs found
Forgiveness of Perpetrators and Adjustment in Adult Female Sexual Abuse Survivors
Clinical Psycholog
The organic geochemistry of ancient sediments, part II
Chemical analysis of sediment and oil hydrocarbon content by gas chromatography and mass spectrometry to establish inception period of bio-organic evolutio
Recommended from our members
HYDROCARBONS OF BIOLOGICAL ORIGIN FROM A ONE-BILLION YEAR OLDSEDIMENT
The isoprenoid hydrocarbons, phytane (C{sub 20}H{sub 42}) and pristane (C{sub 19}H{sub 40}) are present in the oil seeping from the Pre-Cambrian Nonesuch Formation at the White Pine Mine, Michigan. Gas-liquid chromatography and mass spectrometry provide the isolation and identification procedures
Immobilization of aminophenylboronic acid on magnetic beads for the direct determination of glycoproteins by matrix assisted laser desorption ionization mass spectrometry
Lunar Outgassing, Transient Phenomena and The Return to The Moon, I: Existing Data
Herein the transient lunar phenomena (TLP) report database is subjected to a
discriminating statistical filter robust against sites of spurious reports, and
produces a restricted sample that may be largely reliable. This subset is
highly correlated geographically with the catalog of outgassing events seen by
the Apollo 15, 16 and Lunar Prospector alpha-particle spectrometers for
episodic Rn-222 gas release. Both this robust TLP sample and even the larger,
unfiltered sample are highly correlated with the boundary between mare and
highlands, as are both deep and shallow moonquakes, as well as Po-210, a
long-lived product of Rn-222 decay and a further tracer of outgassing. This
offers another significant correlation relating TLPs and outgassing, and may
tie some of this activity to sagging mare basalt plains (perhaps mascons).
Additionally, low-level but likely significant TLP activity is connected to
recent, major impact craters (while moonquakes are not), which may indicate the
effects of cracks caused by the impacts, or perhaps avalanches, allowing
release of gas. The majority of TLP (and Rn-222) activity, however, is confined
to one site that produced much of the basalt in the Procellarum Terrane, and it
seems plausible that this TLP activity may be tied to residual outgassing from
the formerly largest volcanic ffusion sites from the deep lunar interior. With
the coming in the next few years of robotic spacecraft followed by human
exploration, the study of TLPs and outgassing is both promising and imperiled.
We will have an unprecedented pportunity to study lunar outgassing, but will
also deal with a greater burden of anthropogenic lunar gas than ever produced.
There is a pressing need to study lunar atmosphere and its sources while still
pristine. [Abstract abridged.]Comment: 35 pages, 3 figures, submitted to Icarus. Other papers in series
found at http://www.astro.columbia.edu/~arlin/TLP
Organic Geochemical Studies. I. Molecular Criteria for Hydrocarbon Genesis
In recent years the search for life-forms at the earliest periods of geological time has been continued not only at the morphological level but also at the molecular level. This has been possible as a result of the increase in the biochemical knowledge and with the advent of analytical techniques that are capable of describing the intimate molecular architecture of individual molecules in acute detail. The fundamental premises upon which this organic geochemical approach rest are the following: that certain molecules, possessing a characteristic structural skeleton, show a reasonable stability to degradation over long periods of geological time; that their structural specificity can be understood in terms of known biosynthetic sequences; and that their formation by any non-biological means is of negligible probability. In this manuscript it is proposed to critically re-examine these premises and to establish criteria whereby one can differentiate molecules derived from biological systems from those that have their origin in non-biological processes. The importance of establishing such criteria lies in the significance these criteria have in determining whether life exists, or has existed, on other planets. Within the very near future it may be possible to provide an initial answer to this question when the first lunar samples are returned to the earth for analysis
Outcomes for 18 to 25-year-olds with borderline personality disorder in a dedicated young adult only DBT programme compared to a general adult DBT programme for all ages 18
Aim
Targeting young adults with borderline personality disorder (BPD) for treatment may carry significant social and clinical benefits. We aimed to evaluate a communityâbased Dialectical Behaviour Therapy (DBT) programme delivered exclusively to young adults with BPD.
Methods
We describe a naturally occurring nonâequivalent, quasiâexperimental comparison of outcomes for young adults (18â25âyears) with BPD following 1 year of treatment in either a young adult only DBT programme or a general adult DBT programme (18+ years). Twentyâfour young adults enrolled in a communityâbased young adult DBT programme open only to 18â to 25âyearâolds with BPD. Another 13 young adults, also 18â25âyears, enrolled in a general adult DBT programme open to all ages above 18âyears. Both treatment conditions offered all modes of standard DBT for 1 year. Participants completed a battery of selfâreport measures on mental health symptoms at baseline and again at treatment completion after 1 year. Discharge rates at 2 years postâtreatment completion were also recorded.
Results
Better outcomes were found on borderline symptom severity and general psychopathology among completers of young adult DBT, with a large effect size for treatment condition as well as greater clinically significant change. Discharge rates from mental health services 24âmonths later were also higher for completers of young adult DBT.
Conclusions
There may be advantages in delivering DBT to young adults in an ageâspecific programme, possibly due to group cohesion. Methodological limitations apply, such as small sample size and nonârandomization. Further controlled research is needed
Safety of betaine as a novel food pursuant to Regulation (EC) No 258/97
Following a request from the European Commission, the EFSA Panelon Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on betaine as a novel food (NF) pursuant to Regulation (EC) No 258/97. The information provided on the composition, the specifications, the batch-to-batch variability, stability and production process of the NF is sufficient and does not raise concerns about the safety of the NF. The NF is proposed to be used in foods intended to meet additional requirements for intense muscular effort with a maximum intake of 2.5 g/day of betaine for sports people above 10 years of age. Based on the lowest BMDL05, which was derived from a chronic toxicity study in rats in which a dose-related increase in platelet counts was observed, and the anticipated daily intake of the NF in the target population, the Margins of Exposure are 3.6 and 5, which are generally regarded as not sufficient. However, the total exposure to betaine from the diet (about 830 mg/day) is not known to be associated with adverse effects. Moreover, no adverse effects on platelet counts were noted in human intervention studies with exposure levels of 4 g/day of betaine for up to 6 months. A significant increase in total and low-density lipoprotein (LDL)-cholesterol concentrations was noted at intakes of 4 g/day of betaine in overweight subjects with metabolic syndrome but not in healthy subjects, nor at intakes of 3 g/day. Thus, considering 4 g/day of betaine as a reference point and applying an uncertainty factor of 10 to account for interindividual variability, an amount of 400 mg/day of betaine in addition to the background exposure is considered as safe. The Panelconsiders that the NF is safe to be used at maximum intake of 400 mg/day in the target population
- âŠ