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Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/106672/1/ana24034.pd

Choosing Wisely: Highest‐cost tests in outpatient neurology

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/98329/1/ana23865.pd

Electrodiagnostic tests are unlikely to change management in those with a known cause of typical distal symmetric polyneuropathy

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138297/1/mus25713_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/138297/2/mus25713.pd

Demonstration of Turnstiles as a Chaotic Ionization Mechanism in Rydberg Atoms

We present an experimental and theoretical study of the chaotic ionization of quasi-one-dimensional potassium Rydberg wavepackets via a phase-space turnstile mechanism. Turnstiles form a general transport mechanism for numerous chaotic systems, and this study explicitly illuminates their relevance to atomic ionization. We create time-dependent Rydberg wavepackets, subject them to alternating applied electric-field "kicks", and measure the electron survival probability. Ionization depends not only on the initial electron energy, but also on the phase-space position of the electron with respect to the turnstile --- that part of the electron packet inside the turnstile ionizes after the applied ionization sequence, while that part outside the turnstile does not. The survival data thus encode information on the geometry and location of the turnstile, and are in good agreement with theoretical predictions.Comment: 4 pages, 6 figures, preprin

A prescription for the Epley maneuver: www.youtube.com?

OBJECTIVES: Video-sharing Web sites are being used for information about common conditions including dizziness. The Epley maneuver (EM) is a simple and effective treatment for benign paroxysmal positional vertigo (BPPV) of the posterior canal. However, the maneuver is underused in routine care. In this study, we aimed to describe and analyze the available information about the EM on youtube.com. METHODS: A YouTube search was performed on August 31, 2011, for videos that demonstrated the entire EM. Detailed data were abstracted from each video and corresponding Web site. Videos were rated on the accuracy of the maneuver by 2 authors, with differences resolved by adjudication. Comments posted by viewers were assessed for themes regarding video use. RESULTS: Of the 3,319 videos identified, 33 demonstrated the EM. The total number of hits for all videos was 2,755,607. The video with the most hits (802,471) was produced by the American Academy of Neurology. Five of the videos accounted for 85% of all the hits. The maneuver demonstration was rated as accurate in 64% (21) of the videos. Themes derived from the 424 posted comments included patients self-treating with the maneuver after reviewing the videos, and providers using the videos as a prescribed treatment or for educational purposes. CONCLUSION: Accurate video demonstration of the Epley maneuver is available and widely viewed on YouTube. Video-sharing media may be an important way to disseminate effective interventions such as the EM. The impact of video Web sites on outcomes and costs of care is not known and warrants future study

Ozone depletion, greenhouse gases, and climate change

This symposium was organized to study the unusual convergence of a number of observations, both short and long term that defy an integrated explanation. Of particular importance are surface temperature observations and observations of upper atmospheric temperatures, which have declined significantly in parts of the stratosphere. There has also been a dramatic decline in ozone concentration over Antarctica that was not predicted. Significant changes in precipitation that seem to be latitude dependent have occurred. There has been a threefold increase in methane in the last 100 years; this is a problem because a source does not appear to exist for methane of the right isotopic composition to explain the increase. These and other meteorological global climate changes are examined in detail

Chaotic ionization of a stationary electron state via a phase space turnstile

The ionization of a highly excited Rydberg atom subjected to a periodic sequence of electric field impulses, or “kicks,” is chaotic. We focus on the dynamics of a single kicking period in order to isolate the ionization mechanism. Potassium Rydberg atoms, prepared in a quasi-one-dimensional state, are exposed to a sequence of ionization kicks, and the total fraction of ionized atoms is then measured. These experimental data are compared to a one-dimensional classical model. The classical analysis reveals that the ionization process is governed by a phase space turnstile—a geometric structure associated with chaotic transport in diverse systems. The turnstile geometry is reflected in the experimental data. Previous work explored the dependence of the turnstile geometry on the kicking period. The present work explores the dependence on the kicking strength. In particular, increasing the kicking strength allows us to observe the stretching of the turnstile lobe as it penetrates the region of phase space occupied by the electronic state, leading to a sharp rise in the total ionization fraction. This work thus highlights the importance of phase space geometry in organizing chaotic transport in atomic Systems

A Reply to: Large Exomoons unlikely around Kepler-1625 b and Kepler-1708 b

Recently, Heller & Hippke argued that the exomoon candidates Kepler-1625 b-i and Kepler-1708 b-i were allegedly 'refuted'. In this Matters Arising, we address these claims. For Kepler-1625 b, we show that their Hubble light curve is identical to that previously published by the same lead author, in which the moon-like dip was recovered. Indeed, our fits of their data again recover the moon-like dip with improved residuals than that obtained by Heller & Hippke. Their fits therefore appear to have somehow missed this deeper likelihood maximum, as well producing apparently unconverged posteriors. Consequently, their best-fitting moon is the same radius as the planet, Kepler-1625 b; a radically different signal from that which was originally claimed. The authors then inject this solution into the Kepler data and remark, as a point of concern, how retrievals obtain much higher significances than originally reported. However, this issue stems from the injection of a fundamentally different signal. We demonstrate that their Hubble light curve exhibits ~20% higher noise and discards 11% of the useful data, which compromises its ability to recover the subtle signal of Kepler-1625 b-i. For Kepler-1708 b-i it was claimed that the exomoon model's Bayes factor is highly sensitive to detrending choices, yielding reduced evidence with a biweight filter versus the original claim. We use their own i) detrended light curve and ii) biweight filter code to investigate these claims. For both, we recover the original moon signal, to even higher confidence than before. The discrepancy is explained by comparing to their quoted fit metrics, where we again demonstrate that the Heller & Hippke regression definitively missed the deeper likelihood maximum corresponding to Kepler-1708 b-i. We conclude that both candidates remain viable but certainly demand further observations.Comment: Under consideration by Nature Astronomy as Matters Arisin

Children and older adults exhibit distinct sub-optimal cost-benefit functions when preparing to move their eyes and hands

"© 2015 Gonzalez et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited"Numerous activities require an individual to respond quickly to the correct stimulus. The provision of advance information allows response priming but heightened responses can cause errors (responding too early or reacting to the wrong stimulus). Thus, a balance is required between the online cognitive mechanisms (inhibitory and anticipatory) used to prepare and execute a motor response at the appropriate time. We investigated the use of advance information in 71 participants across four different age groups: (i) children, (ii) young adults, (iii) middle-aged adults, and (iv) older adults. We implemented 'cued' and 'non-cued' conditions to assess age-related changes in saccadic and touch responses to targets in three movement conditions: (a) Eyes only; (b) Hands only; (c) Eyes and Hand. Children made less saccade errors compared to young adults, but they also exhibited longer response times in cued versus non-cued conditions. In contrast, older adults showed faster responses in cued conditions but exhibited more errors. The results indicate that young adults (18 -25 years) achieve an optimal balance between anticipation and execution. In contrast, children show benefits (few errors) and costs (slow responses) of good inhibition when preparing a motor response based on advance information; whilst older adults show the benefits and costs associated with a prospective response strategy (i.e., good anticipation)

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Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/109317/1/ana24280.pd