Nonlinear optical materials formed by push-pull (bi)thiophene derivatives functionalized with di(tri)cyanovinyl acceptor groups

Studies of the second-order nonlinear optical susceptibilities of six NLOphores bearing di(tri)cyanovinyl acceptor groups linked to (bi)thiophene heterocyclic donor systems were performed for the first time in polymethyl methacrylate (PMMA) matrices with a 1064 nm laser working in the 20 ns time pulse regime. Absorption spectra and DFT calculations were also performed. This multidisciplinary study showed that modulation of the optical (linear and nonlinear) properties can be achieved by increasing the length of the -conjugated heterocyclic system (thiophene vs. bithiophene), the strength of the electron donor groups (HMeO/EtOEt2N) as well as the strength of the electron acceptor moieties (DCV vs. TCV, two vs. three electron withdrawing cyano groups). Due to the relatively high second-order susceptibilities (0.08 to 6.45 pm/V), the studied push-pull chromophores can be denote as very potent NLOphores.Fundação para a Ciência e a Tecnologia (FCT

Introductory clifford analysis

In this chapter an introduction is given to Clifford analysis and the underlying Clifford algebras. The functions under consideration are defined on Euclidean space and take values in the universal real or complex Clifford algebra, the structure and properties of which are also recalled in detail. The function theory is centered around the notion of a monogenic function, which is a null solution of a generalized Cauchy–Riemann operator, which is rotation invariant and factorizes the Laplace operator. In this way, Clifford analysis may be considered as both a generalization to higher dimension of the theory of holomorphic functions in the complex plane and a refinement of classical harmonic analysis. A notion of monogenicity may also be associated with the vectorial part of the Cauchy–Riemann operator, which is called the Dirac operator; some attention is paid to the intimate relation between both notions. Since a product of monogenic functions is, in general, no longer monogenic, it is crucial to possess some tools for generating monogenic functions: such tools are provided by Fueter’s theorem on one hand and the Cauchy–Kovalevskaya extension theorem on the other hand. A corner stone in this function theory is the Cauchy integral formula for representation of a monogenic function in the interior of its domain of monogenicity. Starting from this representation formula and related integral formulae, it is possible to consider integral transforms such as Cauchy, Hilbert, and Radon transforms, which are important both within the theoretical framework and in view of possible applications

Preclinical electrogastrography in experimental pigs

Surface electrogastrography (EGG) is a non-invasive means of recording gastric myoelectric activity or slow waves from cutaneous leads placed over the stomach. This paper provides a comprehensive review of preclinical EGG. Our group recently set up and worked out the methods for EGG in experimental pigs. We gained our initial experience in the use of EGG in assessment of porcine gastric myoelectric activity after volume challenge and after intragastric administration of itopride and erythromycin. The mean dominant frequency in pigs is comparable with that found in humans. EGG in experimental pigs is feasible. Experimental EGG is an important basis for further preclinical projects in pharmacology and toxicology

The effect of particle size on the core losses of soft magnetic composites

In the field of electrical machines, the actual research activities mainly focus on improving the energetic aspects; for this reason, new magnetic materials are currently investigated and proposed, supporting the design and production of magnetic cores. The innovative aspects are related to both hard and soft magnetic materials. In the case of permanent magnets, the use of NdFeB bonded magnets represents a good solution in place of ferrites. For what concerns the soft magnetic materials, the adoption of Soft Magnetic Composites (SMCs) cores permits significant advantages compared to the laminated sheets, such as complex geometries and reduced eddy currents losses. SMC materials are ferromagnetic grains covered with an insulating layer that can be of an organic or inorganic type. The proposed study focuses on the impact of the particle size and distribution on the final material properties. The original powder was cut into three different fractions, and different combinations have been prepared, varying the fractions percentages. The magnetic and energetic properties have been evaluated in different frequency ranges, thus ranking the best combinations. The best specimens were then tested to evaluate the mechanical performances. The preliminary results are promising, but deeper analysis and tests are required to refine the selection and evaluate the improvements against the original composition taken as a reference.In the field of electrical machines, the actual research activities mainly focus on improving the energetic aspects; for this reason, new magnetic materials are currently investigated and proposed, supporting the design and production of magnetic cores. The innovative aspects are related to both hard and soft magnetic materials. In the case of permanent magnets, the use of NdFeB bonded magnets represents a good solution in place of ferrites. For what concerns the soft magnetic materials, the adoption of Soft Magnetic Composites (SMCs) cores permits significant advantages compared to the laminated sheets, such as complex geometries and reduced eddy currents losses. SMC materials are ferromagnetic grains covered with an insulating layer that can be of an organic or inorganic type. The proposed study focuses on the impact of the particle size and distribution on the final material properties. The original powder was cut into three different fractions, and different combinations have been prepared, varying th..

Body indices and basic vital signs in Helicobacter pylori positive and negative persons

It has been hypothesized that Helicobacter pylori (Hp) infection may contribute to reduced stature, risk of hypertension or obesity. The aim was to evaluate body indices in Hp positive and negative persons. A total of 2436 subjects (4–100 years old) were tested for Hp status by 13Curea breath test. Data on height and weight were collected for 84%, and blood pressure for 80% of the study subjects. The prevalence of Hp infection was 41.6%. The odds ratio for a 10-year increase in age was 1.21 (95% CI 1.17–1.25, p-value <0.001). Statistically significant negative association of Hp positivity with body height was most pronounced in the younger age groups, while a positive association of Hp positivity with body mass index was only seen in those aged 15+ years. There was a negative effect of Hp positivity on systolic and diastolic blood pressure in subjects below 25 and a relatively strong positive effect on blood pressure in subjects over 65 years. Residual confounding by social characteristics as a possible explanation for the associations of Hp positivity with height and blood pressure cannot be excluded. Unmeasured factors related to social and family environment may cause the apparent association between Hp positivity and children’s growth and blood pressure