The Effect of Stress Ulcer Prophylaxis on Ventilator-Associated Pneumonia Incidence in the Intensive Care Unit

Ventilator-associated pneumonia (VAP) is one of the most common causes of nosocomial infections in the intensive care unit. Mechanically ventilated patients are at risk for upper gastrointestinal (GI) bleeding. It has been shown in previous studies that acid suppression therapy used for GI prophylaxis may cause the development of bacterial pneumonia. The aim of this review is to evaluate the effect of stress ulcer prophylaxis on VAP incidence in the intensive care unit. (Yogun Bakim Derg 2015; 6: 10-2

High Flow Nasal Oxygen Therapy: From Physiology to Clinic

WOS: 000409974000002High-flow nasal oxygen (HFNO) therapy has several physiological advantages over traditional oxygen therapy devices, including decreased nasopharyngeal resistance, washing out of the nasopharyngeal dead space, generation of positive pressure in the pharynx, increasing alveolar recruitment in the lungs, humidification of the airways, increased fraction of inspired oxygen and improved mucociliary clearance. Recently, the use of HFNO in treating adult critical illness patients has significantly increased, and it is now being used in many patients with a range of different disease conditions. However, there are no established guidelines to direct the safe and effective use of HFNO for critical patients. This review summarizes the positive physiological effects, mechanisms of action, and the clinical applications of HFNO with available published literatures

Can fiberoptic bronchoscopy be applied to critically ill patients treated with noninvasive ventilation for acute respiratory distress syndrome? Prospective observational study

Noninvasive ventilation (NIV) is a cornerstone for the treatment of acute respiratory failure of various etiologies. Using NIV is discussed in mild-to-moderate acute respiratory distress syndrome (ARDS) patients (PaO2/FiO2\u2009>\u2009150). These patients often have comorbidities that increase the risk for bronchoscopy related complications. The primary outcome of this prospective observational study was to evaluate the feasibility, safety and contribution in diagnosis and/or modification of the ongoing treatment of fiberoptic bronchoscopy (FOB) in patients with ARDS treated with NIV