A Design Concept for a Tourism Recommender System for Regional Development

Despite of tourism infrastructure and software, the development of tourism is hampered due to the lack of information support, which encapsulates various aspects of travel implementation. This paper highlights a demand for integrating various approaches and methods to develop a universal tourism information recommender system when building individual tourist routes. The study objective is proposing a concept of a universal information recommender system for building a personalized tourist route. The developed design concept for such a system involves a procedure for data collection and preparation for tourism product synthesis; a methodology for tourism product formation according to user preferences; the main stages of this methodology implementation. To collect and store information from real travelers, this paper proposes to use elements of blockchain technology in order to ensure information security. A model that specifies the key elements of a tourist route planning process is presented. This article can serve as a reference and knowledge base for digital business system analysts, system designers, and digital tourism business implementers for better digital business system design and implementation in the tourism sector

Temporal model for assessing the quality of public services

The material about the use of business processes to determine the quality of receiving services in a public institution is presents in article. It is proposed to take into account when obtaining a quality not only qualitative assessments, which are connected with the expert assessment and customer opinion and quantitative related to the timing of execution of business processes by employees. Shown mathematical expressions that allow build an automated quality evaluation system

System for Monitoring the Quality of Services Provided by a Public Institution Based on Business Processes

Monitoring the quality of the services provided by public institutions is an important element in improving the effectiveness of the entire system of public services in the Russian Federation. As a rule, monitoring is associated with obtaining quantitative indicators of the level of satisfaction of citizens which characterize the quality of services provided. Monitoring results are the basis for modernizing the service management system. However, this approach allows us to evaluate only one side of the process by which a public institution renders services to the consumer of services (citizens). The other side of the issue is related to monitoring the processes of the institution itself. This direction also allows us to find approaches to improving the quality of service delivery, and to make the work of a state institution more efficient. This article describes the methodology for monitoring the process of providing services in a public institution based on business processes. The description of the activity of the institution in terms of the implementation of services is presented in the form of a set of business processes. It is shown that the main element of business processes that can be measured is the time of their implementation. On this basis, a mathematical model for assessing the quality of public service delivery is constructed, including both qualitative assessments (obtained from experts and clients of the institution) and quantitative assessments of the quality of service delivery based on measuring the time of business processes. The quantitative aspect of the proposed methodology is directly related to the main direction declared by the Government of the Russian Federation – the development of digital economy. As an example, the article considers such a state institution as the Social Insurance Fund of the Russian Federation

Перспективы инновационного развития рекреационного землепользования Украины в направлении европейской интеграции

The аrticle substantiates the need for the transformation of existing approaches to change the institutional basis for recreational land use. The task of providing innovative development of recreational territories taking into account modern trends and European initiatives on the way to sustainable development of territories is solved. The main obstacles on the way to European integration processes in the sphere of recreational land use are considered. The connection between the sustainable development of the relevant process and its institutional and financial support by the state is substantiated. The main priorities of the correction of the mechanism of management and development of the corresponding territories are determined. Socio-ecological and economic aspects of the European integration processes in Ukraine in social-information, market, basic and normative-legislative directions are taken into account. It is proved that formation of a comprehensive land strategy program can become an effective mechanism for its modernization and introduction of innovative technologies in the field of land relations. In order to develop a strategy for innovative development of recreational land use, the most relevant is the use of foresight research methodology. In the framework of formation of target plants for the purpose of strategy development of recreational land use in the direction of European integration of environmental management processes a scenario is proposed. It combines foresight research methods taking into account the correct use of various methods, which are based on creativity, experience, interaction and actual data. In the conditions of implementing the above-mentioned measures, it is possible to introduce European initiatives in the recreational sector of Ukraine.В статье обоснована необходимость трансформации существующих подходов к изменению институциональной основы рекреационного землепользования. Решается задача обеспечения инновационного развития рекреационных территорий с учетом современных тенденций и европейских инициатив на пути к устойчивому развитию территорий. Рассмотрены основные препятствия на пути к евроинтеграционным процессам в сфере рекреационного землепользования. Обоснована связь устойчивого развития соответствующего процесса с их институциональным и финансовым обеспечением со стороны государства. Определены основные приоритеты коррекции механизма управления и развития соответствующих территорий с учетом социо-эколого-экономических аспектов евроинтеграционных процессов в Украине по следующим направлениям: социально-информационный, рыночный, базовый и нормативно-законодательный. Доказано, что формирование комплексной программы земельного стратегирования может стать действенным механизмом ее модернизации и внедрения инновационных технологий в отрасль земельных отношений. Для разработки стратегии инновационного развития рекреационного землепользования, наиболее актуальным считается использование методологии форсайт-исследований. В рамках формирования целевых установок для обеспечения стратегирования рекреационного землепользования в направлении евроинтеграции процессов природопользования, предложен сценарий, который предполагает сочетание методов форсайт- исследований с учетом правильности использования различных методов, основанных на креативности, опыте, взаимодействии и фактических данных. При условии имплементации вышеуказанных мероприятий станет возможным внедрение европейских инициатив в рекреационную отрасль Украины

Automated Methods for Fiber Diameter Measurement of Fibrous Scaffolds

The purpose of this work was to develop an automated method of measuring fiber diameters of electrospun scaffolds from scanning electron microscopy images of these scaffolds. Several automated methods were developed and evaluated by comparison to known values and data obtained via the standard manual method. Simulated images with known diameters were used as test images to evaluate the accuracy of each measurement technique. Eight scanning electron microscopy images were also used for the evaluation of the automated methods compared to the standard manual method. All diameter measurements were made in pixels. Five new automated methods coded in MATLAB were developed. The five methods varied the approach of identifying edges of fibers as well as assigning edges to single fibers and calculating the distance between edges assigned to the same fiber. One-way analysis of variance and the Tukey-Kramer tests were performed for comparison of all methods per image. The Custom Canny Slopes automated method was shown to accurately approximate the mean diameters in ten simulated images as well as microscopy image of real scaffolds (p\u3c0.05)

EPS8 (epidermal growth factor receptor pathway substrate 8)

Review on EPS8 (epidermal growth factor receptor pathway substrate 8), with data on DNA, on the protein encoded, and where the gene is implicated

Temporal model for assessing the quality of public services

The material about the use of business processes to determine the quality of receiving services in a public institution is presents in article. It is proposed to take into account when obtaining a quality not only qualitative assessments, which are connected with the expert assessment and customer opinion and quantitative related to the timing of execution of business processes by employees. Shown mathematical expressions that allow build an automated quality evaluation system

Increased Tissue Temperature Improves Electro-Transfer Mediated Gene Delivery to Skin

[Introduction] Developing an optimal gene electro-transfer system for delivery of plasmid DNA to the skin in vivo has been challenging with expression often confined in the epithelium requiring high voltage electric fields, which can cause cellular and tissue damage. Minimizing such damage, while optimizing gene expression profiles, are highly desirable for therapeutic applications of gene delivery to the skin. Cell membrane fluidity is temperature dependent, thus moderate temperature elevation can increase membrane fluidity. Utilizing this concept, we developed a novel gene electro-transfer electrode for in vivo applications with ability to heat tissue with a laser integrated into a four pin multi-electrode array, to improve gene delivery efficiency

Modeling Business Processes of the Social Insurance Fund in Information System Runa WFE

Introduction - Business processes are gradually becoming a tool that allows you at a new level to put employees or to make more efficient document management system. In these directions the main work, and presents the largest possible number of publications. However, business processes are still poorly implemented in public institutions, where it is very difficult to formalize the main existing processes. Us attempts to build a system of business processes for such state agencies as the Russian social insurance Fund (SIF), where virtually all of the processes, when different inputs have the same output: public service. The parameters of the state services (as a rule, time limits) are set by state laws and regulations. The article provides a brief overview of the FSS, the formulation of requirements to business processes, the justification of the choice of software for modeling business processes and create models of work in the system Runa WFE and optimization models one of the main business processes of the FSS. The result of the work of Runa WFE is an optimized model of the business process of FSS