Analysis between Adrenal MRI Mass Size and 1 mg Dexamethasone Suppression Test in Patients with Adrenal Incidentaloma

This study aimed to investigate the correlation of adrenal magnetic resonance imaging (MRI) mass size and 1 mg dexamethasone suppression test results in patients with adrenal incidentaloma diagnosis. Eighty-six patients (82.6% female) with incidentally discovered adrenal masses, diagnosed and treated in the Department of Endocrinology Bakirkoy Dr. Sadi Konuk Education and Research Hospital between June and August 2017, were included in the analysis. All the patients evaluated for their hormonal functionality. 24-h urinary excretion of cortisol did not correlate with tumor size. But there was a positive correlation between longer adrenal nodule diameter and metanephrine, and there was a negative correlation between shorter adrenal nodule diameter and renin levels. We found that smaller and clinically “silent” tumors often do not demonstrate subclinical hormonal activity

Examination of eating disorder risk and effective factors in university students

The aim of this study; determine the eating attitudes and behaviors of university students, who are a sensitive population in terms of eating disorders, and to examine some related factors. A structured questionnaire and face-to-face interviews collected the data. The data collection form has two sections: one for sociodemographics and health behaviors, and one for dietary habits and eating disorders using eating disorders scale (REZZY). The questionnaire explained voluntary study participation. The mean age of the 762 university students included in the study was 23.44±5.33 years and 58.40% were female. Variables that one-off analyses suggested might be connected to the risk of developing eating disorders were examined using the logistic regression model. There was a significant and positive correlation between the REZZY-Total (REZZY-T) score, bulimia and food preoccupation (EAT-1) and dieting (EAT-2) (p [Med-Science 2023; 12(3.000): 974-80

The relationship between death risk and nutritional factors in individuals with acute coronary syndrome

There is a relationship between low food intake and risk of death in patients with acute coronary syndrome. In this study aimed to examine the relationship between The Global Registry of Acute Coronary Events (GRACE risk score) and food intake.: 140 men over 35 years of age with Acute Coronary Syndrome were included in the study. The 1-day energy and nutrient consumption of individuals was determined using a 24-hour food consumption recording method. Based on the GRACE risk score classification system, the patients were divided into four quartiles (89.5≥Q1≥72, 102.5≥Q2≥89.5, 117.75≥Q3≥102.51, 152≥Q4≥117.76). The macro and micronutrient intakes of individuals were compared between the four groups. Nutrient intake decreased in the group with the highest grace risk score. inadequate nutrient intake further increased the GRACE risk score. A negative correlation was found between the GRACE risk score and macro and micronutrients (p [Med-Science 2022; 11(4.000): 1660-7

VITAMIN D LEVELS IN ROUTINE MEDICAL EXAMINATION

Objective: Vitamin D deficiency is a serious public healthcare problem throughout the worldand is related to multiple comorbidities, including osteoporosis, falls, and fractures, particularly in the geriatric population

Retrospective Analysis Of Gestational Trophoblastic Neoplasia: Single Center Experience

This study aims to analyze the clinicopathologic characteristics and treatment outcomes of our patients with gestational trophoblastic neoplasia (GTN) and to present our real-life experience. A total of 32 patients with GTN diagnosed according to the FIGO 2002 criteria followed in Zekai Tahir Burak Women's Health Training and Research Hospital between 2011-2018 were included. Demographic features, treatment outcomes, and survival were analyzed retrospectively. The median follow up time was 32.1 (3.3-76.9) months. Of the 32 patients, 27 (84.4%) were defined as low-risk GTN (risk score = 7) according to the FIGO risk score. Seventeen (62.9%) patients with low-risk GTN achieved complete remission (CR) with single agent MTX. CR rate was 60% (12/20) in patients receiving weekly MTX and 71.4% (5/7) in MTX-FA eight-day regimen (p= 0.590). Of the 9 MTX resistant patients, 8 (88.8%) achieved CR with second-line Actinomycin D (ActD). Three (60%) out of the five high-risk GTN patients acquired CR with first-line EMA-CO (etoposide, MTX, plus ActD alternating with cyclophosphamide and vincristine). In the follow-up period one patient (3.1%) had recurrent disease. By the data cut off date, all of the patients were alive and CR could not be achieved in one (3.1%) patient. All patients with low-risk GM achieved CR with sequential therapies ultimately. Therefore, single agent MTX is a reasonable option in the initial treatment of low-risk GTN. Moreover, Actinomycin D is highly effective in patients with low-risk GTN who are resistant to MTX.WoSScopu

A Device for the Functional Improvement of Lagophthalmos

A new device was tested on rabbits for the improvement of lagophthalmos, which causes dryness and irritation of the eye and may cause blindness if untreated. In the presented study, 14 rabbits were injected with local anesthetic to induce temporary facial palsy leading to lagophthalmos on one side. To provide functionality to the upper eyelids, ferromagnetic steel plates were either implanted within the eyelid or taped on the eyelid surface. The device detected blinking in the nonparalytic side and moved the anesthetized paralytic eyelid by pulling the steel plate electromagnetically. The control group (n = 5) did not wear the device, and they could not shut their paralytic eyelids. The treatment group with the external placement of the metal plate (n = 4) and the treatment group with the implant (n = 5) wore the device for artificial blinking. All animals were observed during the experiments, and blinking was recorded on digital video. The data collected from video records were analyzed to test the statistical difference of blinking between control and the treated groups. The results showed that the treatment groups could artificially move their paralytic eyelids. Furthermore, the treatment group with the implant showed a noticeable similarity in eyelid position compared with healthy (nonparalytic) eyes

Early extracorporeal life support experiences in 2 tertiary pediatric intensive care units in Turkey

WOS: 000343068800009PubMed ID: 25539543Background/aim: Extracorporeal membrane oxygenation (ECMO) is a unique life-support modality offered to patients unresponsive to optimal medical therapy. The aim of this study was to evaluate early experiences with ECMO support in 2 tertiary Turkish pediatric intensive care units (PICUs). Materials and methods: We retrospectively evaluated a total of 10 ECMO-supported patients between March 2012 and March 2013 in Marmara and Ege University Hospital PICUs. We reported data regarding demographics, laboratory and diagnostic information, and the clinical course of the patients. Results: The study consisted of 6 males and 4 females from 5 months to 14 years of age (mean age: 0.5 +/- 5.01 years) supported with ECMO. Out of the 10 patients, 8 were on venovenous ECMO for respiratory failure and 2 received venoarterial ECMO for cardiac failure. Mean ECMO and intensive care duration was 11.1 +/- 7.3 days and 23.5 +/- 17.8 days, respectively. Bleeding was the most common complication (60%). Forty percent of the patients were weaned from ECMO, among which 50% were discharged in good health without sequelae. Conclusion: Initial experiences build the learning curve of institutions, and our early results are encouraging. Giving time to heal to the right patient at the right time is the key to success

Bilgisayarli tomografi görüntülerinde konvolüsyonel sinir aǧlari ile dalak siniflandirilmasi

The automated segmentation systems have been evolving from experimental to clinical applications in radiology. By taking advantage of these, radiologists can increase diagnostic accuracy in their interpretations. In this work we proposed a convolutional neural network based spleen segmentation system. Automatically segmented spleen had an 76.7% sensitivity, 99.8% specificity, 94.7% positive prediction value, 99.9% negative prediction value and 99.8% accuracy. © 2019 IEEE