Description of suicide ideation among older adults and a psychological profile: a cross-sectional study in Turkey

6th Ibero-American Congress on Qualitative Research (CIAIQ) / 2nd International Symposium on Qualitative Research (ISQR) -- JUL 12-14, 2017 -- Salamanca, SPAINWOS: 000469777600027PubMed: 31166519This study investigates the suicidal ideation and the possible causes for suicidal behaviour in the elderly. Subjects were 150 patients aged 65 and older who were evaluated using the sociodemographic data collection forms, Geriatric Depression Scale (GDS), Suicidal Ideation Scale (SIS), Reasons for Living Inventory (RLI), and Beck Hopelessness Scale (BHS). of 150 patients, 72.7% were women and 27.3% were men, ages ranged from 65 to 88 years. Suicidal ideation was noted in 30.7% of patients. When the mean of BHS total score between patients with and without suicidal ideation and the mean of BHS subscale's feelings and expectations regarding the future and loss of motivation and hope in terms of subscales were evaluated between the groups with and without suicidal ideation, the scores had a significant difference. When RLI was evaluated in terms of total scores, the suicidal ideation mean score was 243.74 +/- 32.28, while the non-suicidal ideation mean score was 267.27 +/- 24.36. There was a significant relationship between the two groups. We found low level of education, low level of reasons for living and higher psychiatric morbidity (generalized anxiety disorder and comorbid depressive disorder) in with suicidal ideation in the elderly

PROLIDASE ACTIVITY AND OXIDATIVE STRESS IN PATIENTS WITH MAJOR DEPRESSIVE DISORDER

Background: The aim of the current study was to determine whether the serum prolidase levels are associated with the etiopathogenesis of depression. Subjects and methods: This study included 29 patients with major depressive disorder (MDD), who were consecutively recruited from the psychiatric outpatient clinic, and 30 healthy individuals recruited from the general community. Each patient underwent a detailed diagnostic evaluation by two psychiatrists using the Structured Clinical Interview for DSM-IV (SCID-I). Serum prolidase activity and oxidative parameters were measured in the patient and control groups. The severity of depressive symptoms was assessed using the Hamilton Depression Rating Scale. Results: Serum prolidase level was significantly higher in patients with MDD compared to healthy subjects (p<0.001). Total Oxidant Status (TOS) levels and Oxidative Stress Index (OSI) were also significantly higher in patients with MDD (p<0.001), whereas no significant difference was observed between the groups in the TAS levels (p=0.297). Serum prolidase level did not show any correlation with markers of oxidative stress in patients with MDD. Conclusion: Increased serum prolidase levels in patients with MDD may be interpreted as the interaction of prolidase activity, glutamate transmission and oxidative stress. It is suggested that prolidase activity is involved in the etiopathogenesis of depressive disorder

Do body mass index, hormone profile and testicular volume effect sperm retrieval rates of microsurgical sperm extraction in the patients with nonobstructive azoospermia?

WOS: 000436167000005PubMed ID: 29733793Objective: We aimed to evaluate the effect of body mass index (BMI), follicle stimulating hormone (FSH), and luteinizing hormone (LH) levels and the mean testicular volume on sperm retrieval rates in microsurgical sperm extraction (microTESE) in the patients with nonobstructive azoospermia (NOA). Material and methods: The data of 282 infertile patients with NOA were analysed retrospectively. The patients with normal karyotype and no Y microdeletions were included in the study. The patients were classified according to their BMI scores and the medical history, physical examination and hormonal parameters were evaluated. The overall data were processed statistically with chi-square and logistic regression analysis and the relation between preoperative findings and sperm retrieval rates was investigated. Results: The sperm retrieval rate of 282 patients after microTESE was found as 41.1%. There was no statistically significant difference in sperm retrieval rates among the subgroups classified according to BMI. FSH and LH levels and the mean testicular volume and pathologic findings were significantly correlated with sperm retrieval rates. Conclusion: Finally significant correlation was determined between sperm retrieval rates and FSH, and LH levels and testicular volumes but no statistically significant difference was found in sperm retrieval rates among BMI groups

Quality of life, problem solving, focus of control and anger tendency in the patients with acne

Ozturk, Ahmet/0000-0002-9854-7586WOS: 000348823600003Background and Design: in this study, we evaluated anxiety and depression levels, levels of problem solving, focus of control, tendency to anger and quality of life in patients with acne as well as the association between those parameters and the clinical features of acne. Materials and Methods: Fifty-two patients with mild to severe acne vulgaris and 46 healthy controls were enrolled. Acne severity was graded in all patients by a dermatologist. the Montgomery-Asberg Depression Rating Scale (MADRS), Hamilton Anxiety Rating Scale (HAM-A), Brief Symptom Inventory (BSI), Problem Solving Inventory (PSI), the State-Trait Anger Scale (STAS), Rotter's Internal-External Focus of Control Scale (RIELCS) and the Short Form 36-Item Health Survey (SF-36) were applied to all participants. Results: in our study, we found out that anxiety and depression scores were significantly higher in patients with acne vulgaris than in controls. in BSI, anxiety disorders, depression, interpersonal sensitivity, and paranoid thoughts scores were significantly higher in patients with acne than in controls. According to SF-36, physical role difficulty, general health and mental health scores were significantly lower in patients with acne. Conclusion: the results of our study support the previous findings suggesting that acne vulgaris leads to various psychiatric problems, such as depression and anxiety and, adversely affects quality of life of patients

Symptomatic Remission Determines Functional Improvement and Quality of Life in Schizophrenia

WOS: 000391572500008PubMed: 28360807Introduction: Schizophrenia is a chronic illness that negatively affects the quality of life and psychosocial functions. Defined criteria to assess remission in schizophrenia are considered to be useful in the longterm follow-up of patients and in discriminating diagnostic factors. This study investigated the quality of life and functionality in schizophrenia patients in symptomatic remission (R-Sch) and not in remission (NonR- Sch). Methods: Sociodemographic data were collected for 40 R-Sch and 40 Non-R-Sch patients, and the following scales were administered: the Clinical Global Impression-Severity (CGI-S) Scale; Positive and Negative Syndrome Scale (PANSS), World Health Organization Quality of Life Questionnaire-Short Form, Turkish Version (WHOQOL-BREF-TR), Quality of Life Scale for Schizophrenia Patients (QLS), and Global Assessment of Functioning Scale (GAF). Results: the total and all subscale scores of PANSS and the CGI-S score were significantly lower in the R-Sch group than in the NonR- Sch group, whereas the GAF scores and all subscales of QLS and WHOQOL-BREF-TR were significantly higher. Conclusion: This study demonstrates that improvement in symptoms in schizophrenia patients improves quality and functionality in all areas of life, suggesting that an improvement in symptoms is the most important determinant of functional recovery in the treatment of schizophrenia

Vagus nerve stimulation inhibits seizure activity and protects blood-brain barrier integrity in kindled rats with cortical dysplasia

Aims: This study investigates the effects of vagus nerve stimulation (VNS) on seizure severity and blood-brain barrier (BBB) integrity in kindled rats with cortical dysplasia (CD)