Searching for Extra Dimensions in the Early Universe

We investigate extra spatial dimensions ($D = 3+\epsilon$) in the early universe using very high resolution molecular rotational spectroscopic data derived from a large molecular cloud containing moderately cold carbon monoxide gas at Z $\approx 6.42$. It turns out that the $\epsilon$-dependent quantum mechanical wavelength transitions are solvable for a linear molecule and we present the solution here. The CO microwave data allows a very precise determination of $= -0.00000657 \pm .10003032$. The probability that $\neq 0$ is one in 7794, only 850 million years (using the standard cosmology) after the Big Bang.Comment: 17 pages, 2 figure

Do children use different forms of verbal rehearsal in serial picture recall tasks? A multi-method study

Use of verbal rehearsal is a key issue in memory development. However, we still lack detailed and triangulated information about the early development and the circumstances in which different forms of rehearsal are used. To further understand significant factors that affect children’s use of various forms of rehearsal, the present study involving 108 primary school children adopted a multi-method approach. It combined a carefully chosen word length effect method with a self-paced presentation time method to obtain behavioural indicators of verbal rehearsal. In addition, subsequent trial-by-trial self-reports were gathered. Word length effects in recall suggested that phonological recoding (converting images to names - a necessary precursor for rehearsal) took place, with evidence of more rehearsal among children with higher performance levels. According to self-paced presentation times, cumulative rehearsal was the dominant form of rehearsal only for children with higher spans on difficult trials. The combined results of self-paced times and word length effects in recall suggest that ‘naming’ as simple form of rehearsal was dominant for most children. Self-reports were in line with these conclusions. Additionally, children used a mixture of strategies with considerable intra-individual variability, yet strategy use was nevertheless linked to age as well as performance levels

Ways to Greater Happiness: A Delphi Study

In the first round of this Delphi study 14 experts suggested strategies for improving life-satisfaction. In a second round, experts rated these strategies for (a) effectiveness, (b) feasibility and (c) cost-effectiveness. They considered 56 strategies policy makers can use to raise average happiness in a nation and 68 ways in which individuals can raise their own happiness. Experts were informed about the average ratings made by the panel and about the arguments advanced. Then, in a third round, experts made their final judgments. Summed ratings for average effectiveness and feasibility of the strategies ranged between 8.4 and 4.9 on scale 2–10, which means that most of the recommendations were deemed suitable. Agreement was slightly higher on policy strategies than on individual ways to greater happiness. Policy strategies deemed the most effective and feasi

Risk attribution of Campylobacter infection by age group using exposure modelling

Knowledge on the relative importance of alternative sources of human campylobacteriosis is important in order to implement effective disease prevention measures. The objective of this study was to assess the relative importance of three key exposure pathways (travelling abroad, poultry meat, pet contact) for different patient age groups in Switzerland. With a stochastic exposure model data on Campylobacter incidence for the years 2002-2007 were linked with data for the three exposure pathways and the results of a case-control study. Mean values for the population attributable fractions (PAF) over all age groups and years were 27% (95% CI 17-39) for poultry consumption, 27% (95% CI 22-32) for travelling abroad, 8% (95% CI 6-9) for pet contact and 39% (95% CI 25-50) for other risk factors. This model provided robust results when using data available for Switzerland, but the uncertainties remained high. The output of the model could be improved if more accurate input data are available to estimate the infection rate per exposure. In particular, the relatively high proportion of cases attributed to ‘other risk factors' requires further attentio

Simulating the dynamics of linear forests in Great Plains agroecosystems under changing climates

Most forest growth models are not suitable for the highly fragmented, linear (or linearly shaped) forests in the Great Plains agroecosystems (e.g., windbreaks, riparian forest buffers), where such forests are a minor but ecologically important component of the land mosaics. This study used SEEDSCAPE, a recently modified gap model designed for cultivated land mosaics in the Great Plains, to simulate the effects of climate change on the dynamics of such linear forests. We simulated the dynamics of windbreaks with different initial planting species richness and widths flight changes as the selected resulting factor) using current climate data and nested regional circulation models (RegCMs). Results indicated that ( i ) it took 70-80 simulation years for the linear forests to reach a steady state under both normal (present-day) and warming climates; (ii) warming climates would reduce total aboveground tree biomass and the spatial variation in biomass, but increase dominance in the linear forests, especially in the upland forests; (iii) linear forests with higher planting species richness and smaller width produced higher aboveground tree biomass per unit area; and (iv) the same species performed very differently with different climate scenarios, initial planting diversity, and forest widths. Although the model still needs further improvements (e.g., the effects of understory species should be included), the model can serve as a useful tool in modeling the succession of linear forests in human-dominated land mosaics under changing climates and may also have significant practical implications in other systems

Surface charge, fluidity, and calcium uptake by rat intestinal brush-border vesicles

AbstractBiological membrane outer surfaces are negatively charged and interact with positively charged calcium ion during calcium uptake. Positively charged polycations such as polyarginine bind to membranes with high affinity, displacing bound calcium from the membrane. We tested the effect of polyarginine on uptake of calcium by brush-border membrane vecicles and examined the responses in terms of membrane fluidity by electron paramagnetic resonance (EPR). Polyarginine inhibited the saturable component of calcium uptake by a mechanism combining inhibition characteristics of strontium (competitive) and magnesium (non-competitive). Unlike the inhibition of non-saturable calcium uptake by strontium and magnesium, polyarginine increased kD, the rate constant for non-saturable calcium uptake, by a concentration dependent mechanism. These effects of polyarginine on calcium uptake were associated with decreased membrane fluidity at the uptake temperature. These findings are consistent with a role for surface negative charge in determining both saturable and non-saturable calcium uptake. Increased membrane fluidity is associated with decreased saturable and increased non-saturable calcium uptake. Although increased fluidity might be involved in the increased kD for non-saturable uptake, the concentration-specific stimulating effect of polyarginine suggests a gating mechanism