Do Isolated Wetlands Substantially Affect Interstate Commerce?

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Do Isolated Wetlands Substantially Affect Interstate Commerce?

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Coexisting Angiomyolipoma and Renal Cell Carcinoma in a Kidney of an Elderly Woman: Case Report and Review of the Literature

Angiomyolipoma is a well described but relatively uncommon benign renal neoplasm composed of varying admixtures of mature adipose tissue, smooth muscle, and thick-walled blood vessels.[1] The incidence of angiomyolipoma is about 0.3% overall.[2] It frequently occurs in patients with tuberous sclerosis. Even more uncommon is the simultaneous occurrence of angiomyolipoma and renal cell cancer in the same kidney in a patient without tuberous sclerosis

Mortuary Truck

Final report and team photo for Project 20 of ME450, Winter 2009 semester.At the Komfo Anokye Teaching Hospital (KATH) in Kumasi, Ghana, locally made mortuary trucks are used to transport deceased bodies from the crowded hospital rooms to morgues that are in separate buildings. Multiple bodies are usually transported during a single trip to the morgue. Currently the trucks in use are difficult to maneuver, difficult to operate, and create sanitation issues. We have designed and fabricated a new truck that is inexpensive, easy to maneuver, controls bodily fluids, conceals bodies from public view, and performs well in an indoor and outdoor environment with minimal maintenance.Kathleen Sienko (Mechanical Engineering, U of M), Multidisciplinary Design Minor Specialization in Global Health Design (U of M); Mentor: George Fusanihttp://deepblue.lib.umich.edu/bitstream/2027.42/62474/2/ME450 Winter2009 Team Photo - Project 20 - Mortuary Truck.JPGhttp://deepblue.lib.umich.edu/bitstream/2027.42/62474/1/ME450 Winter2009 Final Report - Project 20 - Mortuary Truck.pd

Novel contrast-enhanced ultrasound imaging in prostate cancer

The purposes of this paper were to present the current status of contrast-enhanced transrectal ultrasound imaging and to discuss the latest achievements and techniques now under preclinical testing. Although grayscale transrectal ultrasound is the standard method for prostate imaging, it lacks accuracy in the detection and localization of prostate cancer. With the introduction of contrast-enhanced ultrasound (CEUS), perfusion imaging of the microvascularization became available. By this, cancer-induced neovascularisation can be visualized with the potential to improve ultrasound imaging for prostate cancer detection and localization significantly. For example, several studies have shown that CEUS-guided biopsies have the same or higher PCa detection rate compared with systematic biopsies with less biopsies needed. This paper describes the current status of CEUS and discusses novel quantification techniques that can improve the accuracy even further. Furthermore, quantification might decrease the user-dependency, opening the door to use in the routine clinical environment. A new generation of targeted microbubbles is now under pre-clinical testing and showed avidly binding to VEGFR-2, a receptor up-regulated in prostate cancer due to angiogenesis. The first publications regarding a targeted microbubble ready for human use will be discussed. Ultrasound-assisted drug delivery gives rise to a whole new set of therapeutic options, also for prostate cancer. A major breakthrough in the future can be expected from the clinical use of targeted microbubbles for drug delivery for prostate cancer diagnosis as well as treatmen